SLC6A17 (NM_001010898) Human Untagged Clone

CAT#: SC301515

SLC6A17 (untagged)-Human solute carrier family 6, member 17 (SLC6A17)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC6A17
• Synonyms: MRT48; NTT4
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC301515 representing NM_001010898.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCCGAAGAACAGCAAAGTGACCCAGCGTGAGCACAGCAGTGAGCATGTCACTGAGTCCGTGGCCGAC
  CTGCTGGCCCTCGAGGAGCCTGTGGACTATAAGCAGAGTGTACTGAATGTGGCTGGTGAGGCAGGCGGC
  AAGCAGAAGGCGGTGGAGGAGGAGCTGGATGCAGAGGACCGGCCGGCCTGGAACAGTAAGCTGCAGTAC
  ATCCTGGCCCAGATTGGCTTCTCTGTGGGCCTCGGCAACATCTGGAGGTTCCCCTACCTGTGCCAGAAA
  AATGGAGGAGGTGCTTACCTGGTGCCCTACCTGGTGCTGCTGATCATCATCGGGATCCCCCTCTTCTTC
  CTGGAGCTGGCTGTGGGTCAGAGGATCCGCCGCGGCAGCATCGGTGTGTGGCACTATATATGTCCCCGC
  CTGGGGGGCATCGGCTTCTCCAGCTGCATAGTCTGTCTCTTTGTGGGGCTGTATTATAATGTGATCATC
  GGGTGGAGCATCTTCTATTTCTTCAAGTCCTTCCAGTACCCGCTGCCCTGGAGTGAATGTCCTGTCGTC
  AGGAATGGGAGCGTGGCAGTGGTGGAGGCAGAGTGTGAAAAGAGCTCAGCCACTACCTACTTCTGGTAC
  CGAGAGGCCTTGGACATCTCTGACTCCATCTCGGAGAGTGGGGGCCTCAACTGGAAGATGACCCTGTGC
  CTCCTCGTGGCCTGGAGCATCGTGGGGATGGCTGTCGTTAAGGGCATCCAGTCCTCGGGGAAGGTGATG
  TATTTCAGCTCCCTCTTCCCCTACGTGGTGCTGGCCTGCTTCCTGGTCCGGGGGCTGTTGCTGCGAGGG
  GCAGTTGATGGCATCCTACACATGTTCACTCCCAAGCTGGACAAGATGCTGGACCCCCAGGTGTGGCGG
  GAGGCAGCTACCCAGGTCTTCTTTGCCTTGGGCCTGGGCTTTGGTGGTGTCATTGCCTTCTCCAGCTAC
  AATAAGCAGGACAACAACTGCCACTTCGATGCCGCCCTGGTGTCCTTCATCAACTTCTTCACGTCAGTG
  TTGGCCACCCTCGTGGTGTTTGCTGTGCTGGGCTTCAAGGCCAACATCATGAATGAGAAGTGTGTGGTC
  GAGAATGCTGAGAAAATCCTAGGGTACCTTAACACCAACGTCCTGAGCCGGGACCTCATCCCACCCCAC
  GTCAACTTCTCCCACCTGACCACAAAGGACTACATGGAGATGTACAATGTCATCATGACCGTGAAGGAG
  GACCAGTTCTCAGCCCTGGGCCTTGACCCCTGCCTTCTGGAGGACGAGCTGGACAAGTCCGTGCAGGGC
  ACAGGCCTGGCCTTCATCGCCTTCACTGAGGCCATGACGCACTTCCCCGCCTCCCCGTTCTGGTCCGTC
  ATGTTCTTCTTGATGCTTATCAACCTGGGCCTGGGCAGCATGATCGGGACCATGGCAGGCATCACCACG
  CCCATCATCGACACCTTCAAGGTGCCCAAGGAGATGTTCACAGTGGGCTGCTGTGTCTTTGCATTCCTC
  GTGGGGCTGTTGTTCGTCCAGCGCTCCGGAAACTACTTTGTCACCATGTTCGATGACTACTCGGCCACC
  CTGCCACTCACTCTCATCGTCATCCTTGAGAACATCGCTGTGGCCTGGATTTATGGAACCAAGAAGTTC
  ATGCAGGAGCTGACGGAGATGCTGGGCTTCCGCCCCTACCGCTTCTATTTCTACATGTGGAAGTTCGTG
  TCTCCACTATGCATGGCTGTGCTCACCACAGCCAGCATCATCCAGCTGGGGGTCACGCCCCCGGGCTAC
  AGCGCCTGGATCAAGGAGGAGGCTGCCGAGCGCTACCTGTATTTCCCCAACTGGGCCATGGCACTCCTG
  ATCACCCTCATCGTCGTGGCGACGCTGCCCATCCCTGTGGTGTTCGTCCTGCGGCACTTCCACCTGCTC
  TCTGATGGCTCCAACACCCTCTCCGTGTCCTACAAGAAGGGCCGCATGATGAAGGACATCTCCAACCTG
  GAGGAGAACGATGAGACCCGCTTCATCCTCAGCAAGGTGCCCAGTGAGGCACCTTCCCCCATGCCCACT
  CACCGTTCCTATCTGGGGCCCGGCAGCACATCACCCCTGGAGACCAGCGGTAACCCCAATGGACGCTAT
  GGGAGCGGCTACCTGCTGGCCAGCACCCCTGAGTCGGAGCTGTGA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001010898
• Insert Size: 2184 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001010898.2
• RefSeq Size: 6422 bp
• RefSeq ORF: 2184 bp
• Locus ID: 388662
• UniProt ID: Q9H1V8
• Cytogenetics: 1p13.3
• Protein Families: Druggable Genome, Transmembrane
• MW: 81 kDa
• Gene Summary: The protein encoded by this gene is a member of the SLC6 family of transporters, which are responsible for the presynaptic uptake of most neurotransmitters. The encoded vesicular transporter is selective for proline, glycine, leucine and alanine. In mouse, the strongest expression of this gene was in cortical and hippocampal tissues where expression increased during embryonic brain development and peaked postnatally. Defects in this gene cause a form of autosomal recessive intellectual disability. [provided by RefSeq, Jul 2017]