TMTC1 (NM_175861) Human Untagged Clone

CAT#: SC128238

TMTC1 (untagged)-Human transmembrane and tetratricopeptide repeat containing 1 (TMTC1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TMTC1
• Synonyms: ARG99; OLF; TMTC1A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_175861 edited
  GGGAGCTCGCGGCGGGTCCAGCTGCCGCAGCACCATGCCCGAGCCCCCCTCCGGGCAGAC
  GCCGCGCGCCGCCGGGGCCCCGGTAGGGGAGGATGCCAGACGCCCGGGAGAGGCCAGGGC
  AGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGAC
  CGCACACCCTCCCGGCGGCGGGGCTGCGGGCTCGCGCCGGCCGGGGCCGCGGCGCTGCTG
  GCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGAC
  GTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATC
  TTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGG
  CCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTAC
  TTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGT
  GATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTA
  CATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGT
  CTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGG
  GGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACC
  TGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGAC
  CTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGC
  CCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAAT
  GGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCA
  CCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGA
  TTCCTCACCTATTCCTACCTCTTGGCCTTCAATGTGTGGCTTCTGCTTGCACCCGTGACC
  CTGTGCTATGACTGGCAGGTCGGCAGTATTCCTCTGGTAGAGACCATATGGGACATGCGG
  AACTTAGCCACCATCTTTCTGGCGGTTGTGATGGCCTTATTGAGCCTGCACTGCTTAGCA
  GCCTTTAAGAGACTGGAGCACAAGGAGGTTTTAGTCGGCTTGTTGTTCCTGGTGTTCCCG
  TTCATTCCAGCCAGCAACCTCTTCTTCAGGGTGGGTTTTGTGGTGGCGGAGAGAGTCCTT
  TACATGCCTAGCATGGGCTACTGCATCCTTTTTGTGCACGGACTGAGCAAGCTCTGCACT
  TGGCTGAATCGATGTGGGGCCACCACCCTGATTGTGTCCACTGTGTTGCTGCTGTTGCTT
  TTCTCTTGGAAAACTGTGAAACAGAATGAAATTTGGCTGTCAAGAGAGTCCCTATTCAGG
  TCTGGAGTTCAAACTCTGCCCCACAATGCCAAGGTTCACTACAACTATGCCAATTTCCTG
  AAGGACCAAGGTCGGAACAAGGAAGCGATCTACCACTACAGAACAGCTCTCAAGTTGTAT
  CCACGCCATGCAAGTGCGCTCAACAACCTTGGAACACTGACGAGAGACACAGCAGAGGCA
  AAGATGTACTATCAGAGGGCTCTCCAGCTCCATCCACAGCATAACCGGGCTCTTTTCAAT
  CTGGGGAATCTCCTCAAGTCCCAGGAGAAAAAGGAAGAAGCTATCACCTTACTGAAGGAT
  TCCATCAAATATGGTCCAGAGTTTGCAGATGCATATTCAAGCTTAGCTTCGTTATTGGCT
  GAGCAGGAGCGGTTTAAAGAAGCTGAAGAAATATACCAAACTGGAATAAAGAACTGTCCA
  GACAGCTCAGATTTACACAACAACTATGGGGTTTTCTTAGTTGATACTGGCTTACCAGAA
  AAGGCAGTGGCCCATTACCAGCAGGCCATCAAACTTAGCCCCAGTCATCACGTGGCCATG
  GTGAACTTGGGAAGACTCTACAGGTCACTGGGAGAGAACAGCATGGCTGAAGAATGGTAC
  AAGCGCGCCCTGCAGGTGGCACACAAAGCTGAGATATTGTCACCTTTGGGAGCACTGTAT
  TACAACACTGGCCGATACGAAGAGGCTTTGCAGATTTACCAGGAAGCTGCAGCACTTCAG
  CCTTCTCAGAGGGAGCTCCGCTTGGCACTGGCTCAGGTTTTGGCCGTGATGGGTCAGACA
  AAAGAAGCTGAAAAGATGACCAATCACATTGTGTCAGAGGAGACCGGATGCCTTGAATGC
  TATCGCCTCTTGTCAGCCATCTATAGCAAGCAGGAGAACCACGACAAGGCACTTGATGCT
  ATAGACAAGGCTCTCCAGCTGAAACCAAAGGACCCAAAAGTCATTTCTGAACTTTTTTTC
  ACAAAAGGAAACCAATTAAGAGAGCAGAACCTTCTCGACAAAGCTTTTGAGAGCTATAGA
  GTGGCTGTGCAACTAAACCCAGACCAAGCACAGGCCTGGATGAACATGGGTGGCATCCAA
  CACATCAAGGGAAAATATGTGTCTGCAAGAGCTTATTATGAGAGAGCCTTACAGCTGGTT
  CCAGACAGCAAACTGCTGAAGGAAAATCTTGCCAAATTGGATCGCCTAGAAAAACGATTA
  CAAGAAGTTCGAGAAAAGGATCAAACATAGCACCACCGTCTGACCCAACCTCATAGGATA
  ATGTGGTGCCTCTGAAAGGGGAGTGATGGAAGCCTTGCTTTCACATCAGCAGGGGCACAA
  CTAATGAGATTTTCTCTCATTCCGAGTTCAGGGTGACACATTTTGGGACATCTGCTGGTA
  GCCCAGTGCTGAAGGACTTGCTTTTCCATGAAGAAGACGAAAACAGCAAACAAGGGCAAG
  AAGGTCTGAGAGGGAAGGAGAATGACATTTACACATTTTACAGATTTTTGTTTGGTTTAA
  CTCCAGATTTCTCTTGATATATCTCTGTGCTTTTGAGACCTGGAGATCTAATTCTGTTTA
  GACATTTTTTGTCCCAGAAATACAGAAGCTTGAAATGCTATGAAGGCAGAGCTTCTATTC
  TTTATGGGATGAAATATTTCAAAAGAGGATAAATCCTCTGTGGTAAGCCATTTGGAAAAT
  CCTACCAAGAATTGGCTTATTTAATTTTCCAGAACCAGGAATGAGTATCTAATAGCTTTT
  ATAGAACCTTCCAGAATATGTGGGGAAAAAGGGCTATTGCTAAGTGAGCTTTATCTAATA
  TCCTCCTAAGAGTTTTACTAGTGCTTTTTTGAGGAATTACAGGGAAGCTCCTGGAATTGT
  ACATGGATATCTTTATCCCTAGGGGGAAATCAAGGAGCTGGGCACCCCTAATTCTTTATG
  GAAGTGTTTAAAACTATTTTAATTTTATTACAAGTATTACTAGAGTAGTGGTTCTACTCT
  AAGATTTCAAAAGTGCATTTAAAATCATACATGTTCCCGCCTGCAAATATATTGTTATTT
  TGGTGGAGAAAAAAATAGTATATTCTACATAAAAAATTAAAGATATTAACTAAGAAAAAA
  AAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >Reverse primer walk for NM_175861 unedited
  TTAACCAGCCACTCCAAACCCGTGNAGCCTGTCTCTTTCACCAGCATCGCACAAGGTCCC
  CAGNAAACAAACTGAGCAGCAANAAGAAGGGAGACACCGTGGAAGGGAAACTTCCCCCAA
  CACAGCCCTGATCCAGACTCCTGTTGTACGAGAGAAAGGCCAATAGAAACAGCAGACACG
  CTAACACGTCCGCTCTGCCAACGATCCCAGCCACCGCCTCAGTATGAATAGGATGTACAG
  CAAAAAGCAATGCCGTTACAAAAGCAAGTCCACGATTCTTGAAGACAGTTTTATCACAGG
  TGTACATCAGCACAAGAGTCACTAAGCAGTGTAAAATTATATTTACTGCATGAAAGTAGA
  ATGGGTTCATACCAGTCAAAAATATGTTTAGCTTGAAGGTGAGGACGCAGAGCGGCCGGT
  AGGACTTGTGGCTGGTGTTCTCGGCCATGCCCTTGCCCCAGAAGTCGTTGGTGAAGATGC
  CCCAGCGGAGCGGGGCGCCGGGCCGCACGTCGGGGTTGTTCACGATCGCCCACACGTCGT
  CGTGCACGAACTCGCCCTGCAAGGAGCGGCCGTAGCACAGGCAGCTTGCCCCGGCCAGCA
  GCGCCGCGGCCCCGGCCCGCGCGAGCCCGCAACCCCGCCGCCGGGAGGGTGTGCGGTCCC
  CGCCGCCGCCTCGGGCAGAGGTGGTCACCACCATTGTGCCCGCGCCGCCGCTGCTGCCCT
  GGCCTCTCCCCGGCGTCTGGCATCCTTCCCTACCGGGCCCCGGGCGCCCGCGGCGTCTGC
  CCGGAAGGGGCCTCGGGCCATGTTGCTGCGGCAGCTGGACCCGCCCCAGCTCCCCCCTCG
  GGCCAAAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_175861 unedited
  NANAGCACTGGGGCAGGGTCACAGGGATGCCACCCGGGNTCTGTTCAGGAAACAGCTATG
  ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTCTTAGTTAATATCTTT
  AATTTTTTATGTAGAATATACTATTTTTTTCTCCACCAAAATAACAATATATTTGCAGGC
  GGGAACATGTATGATTTTAAATGCACTTTTGAAATCTTAGAGTAGAACCACTACTCTAGT
  AATACTTGTAATAAAATTAAAATAGTTTTAAACACTTCCATAAAGAATTAGGGGTGCCCA
  GCTCCTTGATTTCCCCCTAGGGATAAAGATATCCATGTACAATTCCAGGAGCTTCCCTGT
  AATTCCTCAAAAAAGCACTAGTAAAACTCTTAGGAGGATATTAGATAAAGCTCACTTAGC
  AATAGCCCTTTTTCCCCACATATTCTGGAAGGTTCTATAAAAGCTATTAGATACTCATTC
  CTGGTTCTGGAAAATTAAATAAGCCAATTCTTGGTAGGATTTTCCAAATGGCTTACCACA
  GAGGATTTATCCCTCTTTTGAAATATTTCATCCCATAAAGAATAGAAGCTCTGCCTTCAT
  AGCATTTAAGGCTTCTGTATTTCTGGGGACAAAAAATGTCTAAACAAGAATTAGATCTCC
  AGGTTTTAAAAGCCCCGAGTTTTTTCAAGAGGAATCTGGAGTAAACCCAACAAAAATCTG
  GAAAATGGGTAATGTCATTTTCCTTCCTCTTAAACACTTTTGCCCTTGGTTGGTGTTTCC
  GGCTTCTTACGGGAAAAACAAGTCCTTTCACCCTGGGCTACCCACAAATTGTCCAAAATG
  TTTCCCCCT
  
• Restriction Sites: Please inquire
• ACCN: NM_175861
• Insert Size: 3700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_175861.2, NP_787057.2
• RefSeq Size: 8821 bp
• RefSeq ORF: 2325 bp
• Locus ID: 83857
• UniProt ID: Q8IUR5
• Cytogenetics: 12p11.22
• Protein Families: Transmembrane
• Gene Summary: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.