PITRM1 (NM_014968) Human Untagged Clone

CAT#: SC127612

PITRM1 (untagged)-Human pitrilysin metalloproteinase 1 (PITRM1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PITRM1
• Synonyms: hMP1; KIAA1104; metalloprotease 1; metalloprotease 1 (pitrilysin family); MGC138192; MGC141929; MP1; OTTHUMP00000044698; pitrilysin metallopeptidase 1; pitrilysin metalloproteinase 1; PreP; PreP peptidasome
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014968, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGAAATCTTCCTTCCAGTACATAGCTTCTTGCTGGAACCATGATGGGGACCCTGTGGAGCTCTTGA
  AGTTGGGAAATCAGTTAGCTAAATTCAGACAGTGCCTGCAGGAAAATCCAAAATTTTTGCAAGAAAAAGT
  AAAACAGTATTTTAAGAATAACCAGCATAAGCTGACTTTATCGATGAGGCCAGATGACAAGTATCACGAG
  AAGCAGGCACAGGTGGAAGCCACGAAGCTCAAGCAGAAGGTCGAGGCTCTGTCCCCCGGAGACAGGCAGC
  AGATCTACGAGAAAGGTCTAGAATTACGGAGTCAACAAAGCAAACCTCAAGATGCCTCTTGTCTGCCAGC
  GTTGAAAGTTTCCGATATTGAACCCACCATACCTGTCACAGAGTTGGACGTGGTCCTGACAGCTGGAGAT
  ATCCCTGTTCAGTACTGCGCCCAGCCCACCAATGGCATGGTGTATTTCCGGGCCTTCTCCAGCCTGAACA
  CACTCCCCGAGGAGCTGAGGCCCTATGTGCCCCTCTTCTGCAGCGTCCTCACCAAGCTGGGCTGCGGCCT
  TCTTGACTACCGGGAGCAGGCTCAGCAGATAGAATTGAAGACCGGAGGGATGAGTGCTTCTCCCCACGTG
  CTCCCCGACGACTCACACATGGACACCTACGAGCAGGGTGTGCTTTTCTCCTCTCTCTGCCTGGATCGAA
  ACCTGCCAGACATGATGCAGCTATGGAGTGAAATATTTAACAACCCGTGCTTTGAAGAAGAGGAGCACTT
  CAAGGTGCTGGTGAAGATGACCGCCCAGGAGCTCGCCAATGGAATTCCTGACTCTGGGCACCTGTACGCA
  TCCATCAGGGCAGGCCGGACCCTCACGCCCGCAGGGGACCTGCAGGAGACCTTCAGCGGGATGGATCAGG
  TGCGGCTGATGAAGAGGATTGCAGAAATGACAGATATCAAACCCATCCTGAGGAAGCTCCCACGTATCAA
  GAAACACTTGTTAAATGGTGATAATATGAGGTGTTCAGTGAATGCGACTCCTCAGCAGATGCCTCAGACA
  GAAAAAGCGGTCGAAGACTTCCTTAGAAGCATCGGTCGGAGTAAAAAGGAACGGAGGCCTGTGCGCCCAC
  ACACGGTCGAGAAACCTGTGCCCAGCAGCTCTGGTGGAGATGCCCACGTTCCCCATGGCTCCCAGGTCAT
  TAGGAAGCTGGTCATGGAACCCACCTTCAAGCCCTGGCAGATGAAGACTCACTTCCTGATGCCCTTCCCG
  GTGAATTACGTGGGTGAATGCATCCGAACTGTCCCCTACACGGACCCAGATCATGCCAGTCTTAAAATCC
  TTGCACGTTTGATGACTGCCAAATTCTTGCATACAGAAATTCGAGAAAAAGGCGGTGCTTATGGTGGAGG
  CGCAAAACTCAGCCACAATGGGATTTTCACCCTTTACTCTTACAGGGACCCAAATACAATAGAGACGCTC
  CAGTCTTTTGGGAAGGCTGTCGACTGGGCTAAGTCTGGAAAATTCACACAGCAAGACATCGACGAAGCCA
  AACTTTCTGTCTTCTCAACCGTAGATGCTCCTGTCGCTCCTTCAGACAAAGGAATGGACCACTTCTTGTA
  CGGCCTCTCGGATGAGATGAAGCAGGCCCACAGAGAGCAGCTCTTTGCTGTCAGCCACGACAAGCTCCTG
  GCCGTGAGCGATAGATACCTCGGCACTGGGAAGAGCACACACGGCCTGGCCATCCTCGGACCCGAGAACC
  CGAAAATTGCCAAGGACCCATCCTGGATCATCCGATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014968 unedited
  GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTTGATTGAAT
  CTGGCCTTGGCACAGACTTTTCTCCTGATGTTGGATATAATGGCTACACGAGGGAGGCCT
  ACTTTAGTGTCGGCCTCCAAGGGATTGTGGAGAAAGACATTGAGACCGTCAGAAGCCTCA
  TAGACAGAACGATTGATGAAGTAGTTGAGAAAGGATTTGAAGATGATCGAATTGAGGCTT
  TACTTCATAAAATTGAAATACAGATGAAACATCAGTCTACCAGCTTTGGGCTGATGCTGA
  CATCATACATAGCTTCTTGCTGGAACCATGATGGGGACCCTGTGGAGCTCTTGAAGTTGG
  GAAATCAGTTAGCTAAATTCAGACAGTGCCTGCAGGAAAATCCAAAATTTTTGCAAGAAA
  AAGTAAAACAGTATTTTAAGAATAACCAGCATAAGCTGACTTTATCGATGAGGCCAGATG
  ACAAGTATCACGAGAAGCAGGCACAGGTGGAAGCCACGAAGCTCAAGCAGAAGGTCGAGG
  CTCTGTCCCCCGGAGACAGGCAGCAGATCTACGAGAAAGGTCTAGAATTACGGAGTCAAC
  AAAGCAAACCTCAAGATGCCTCTTGTCTGCCAGCGTTGAAAGTTTCCGATATTGAACCCA
  CCATACCTGTCACAGAGTTGGACGTGGTCCTGACAGCTGGAGATATCCCTGTTCAGTACT
  GCGCCCAGCCCACCAATGGCATGGTGTATNTNCGGGCCTTCTNNCAGCCTGACACACTCC
  CCCGAGGAGCTGAGGCCTATGTGCCCCTCTTCTGCAGCGTNCTCACCAAGCTGGGCTGCG
  GGCTTCTTGACTACCGGNAGCAGGCTCAGCANATAGAATTTGAGACCGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014968 unedited
  TATGTACCGCGCGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCAGATTGCCCT
  TTATTTTTAGATTCTTAAATATTCCTAAAATGAGGTAAAACGAGCCTGCCAGTACAAAGT
  GAAAATTCTACATGGTGCATCTTTGGCGCTTCATGCATGATTATTTCAATGAACCTCTTC
  CTGGTCACTCTTAAGATAGATCTGAGTTTTTGACTCGCCAGTCAAGGGCTTTGGCGACAC
  TCAATGACATAATATTCTTGGAAAAAGCAGTAGCATTTCTGACTTTTCATATTCAGCTCG
  GAGGTGTATTGTCTCGGGCTCCTGTGCAGTCGAGCGCCACGGCTGCTCATTGGATGATCC
  AGGATGGGTCCTTGGCAATTTTCGGGTTCTCGGGTCCGAGGATGGCCAGGCCGTGTGTGC
  TTTTCCCAGTGCCGAGGTACCTATCGCTCACGGCCAGGAGCCTTGTCGTGGCTGACAGCA
  AAGAGCTGCTCTCTGTGGGCCTGCTTCATCTCATCCGAAAGGCCGTCACAACAAGCGGCC
  CCTTCCTTTGTCTGAAGGAGCGACAGGACCCATCTACGGATGATAAGACACAACGTTTGG
  CCTTCTCGATGTCTTGCTGCGGGAATTTTCAAACCTTACCCATTCGACAGCCTTCCCAAA
  GACTGCACCGCTTTTATTGCATATGGGTCCCCGGCACGAACAAAGGTGAAAACTCCATTG
  GGCTGAATCTTACCCCCCCCCCCATAACCCCCCCCTTTTTCTCCCCCCTCCGCCCTGCAC
  AATTCTCGCGTTTTCAAACACGGCCGGGTATTTAAAACCTGCCACCACCCCGGTCCCCCC
  CCGCGGACCACCCCCGAACCACCACCCCCCACCACCCCCCCGCGCGCGCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014968
• Insert Size: 2570 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_014968.1, NP_055783.1
• RefSeq Size: 2579 bp
• RefSeq ORF: 1788 bp
• Locus ID: 10531
• Cytogenetics: 10p15.2
• Domains: Peptidase_M16_C
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease. [provided by RefSeq, Dec 2016]