LARP2 (LARP1B) (NM_032239) Human Untagged Clone

CAT#: SC126851

LARP1B (untagged)-Human La ribonucleoprotein domain family, member 1B (LARP1B), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LARP2
• Synonyms: LARP2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126851 sequence for NM_032239 edited (data generated by NextGen Sequencing)
  ATGGAGAATTGGCCAACACCAAGTGAATTAGTGAACACTGGATTTCAGAGCGTCCTCAGC
  CAAGGAAATAAAAAGCCACAAAATAGAAAAGAAAAAGAAGAGAAGGTTGAAAAGAGAAGT
  AACAGTGACAGCAAAGAAAACCGGGAAACAAAATTAAATGGTCCTGGTGAAAACGTCAGT
  GAGGATGAGGCTCAGTCAAGTAATCAACGTAAGAGAGCTAATAAGCACAAGTGGGTACCA
  CTCCACTTAGATGTTGTAAGATCAGAGAGTCAAGAAAGACCTGGATCCCGGAACAGCTCA
  AGATGTCAACCTGAAGCAAATAAACCAACACATAACAATAGGAGAAATGATACACGAAGT
  TGGAAGCGAGATAGAGAAAAAAGAGATGATCAAGATGACGTTTCCAGTGTGAGAAGTGAG
  GGTGGTAATATCCGAGGTTCCTTTAGAGGTCGAGGAAGAGGCCGAGGACGGGGAAGAGGA
  CGAGGCAGAGGAAATCCTCGATTGAACTTTGATTATTCATATGGTTATCAAGAACATGGT
  GAAAGGACTGATCAACCATTTCAAACAGAACTTAATACCAGTATGATGTATTACTATGAT
  GATGGTACAGGTGTACAGGTGTATCCTGTGGAAGAAGCGTTGCTTAAAGAGTATATTAAG
  CGTCAAATTGAATATTACTTCAGTGTAGAAAATTTGGAACGAGACTTCTTTCTTCGGGGA
  AAGATGGATGAACAAGGTTTCTTGCCTATTTCCCTGATTGCTGGTTTTCAGCGTGTTCAG
  GCTCTCACTACAAACCTTAATCTCATCTTAGAGGCACTGAAGGATAGCACAGAAGTAGAA
  ATTGTGGATGAGAAAATGAGAAAAAAGATAGAACCAGAAAAATGGCCAATTCCAGGCCCT
  CCTCCACGCAGTGTGCCACCAACAGACTTCTCTCAACTGATTGATTGTCCAGAGTTTGTA
  CCAGGCCAAGCCTTTTGCTCACATACAGGTAACATCTTTTCTTCTAGAGCAAACGATGTA
  ACAGTGGGTTATTTGGTCCAATTTACTTACTTATTTATTTATTTTCAGTTTATTTAG
  
  Clone variation with respect to NM_032239.2
  384 g=>a;639 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032239 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGGCACGAGGAAGGGAAATCCCTG
  GACCAAAAAGCCTCCCCAGCACCTGTCCCCAGACACGACAGGTCCGCCACCGCCCCCGCT
  GGAAACCCTGGAGGCAGAATTCGGTTCCCTCAAAATTATAAAAGCAGGAAAGCTCAAGAC
  AAAGAAATCCAACAAGGCTAGTGATTTCAGTGATATGGAGAATTGGCCAACACCAAGTGA
  ATTAGTGAACACTGGATTTCAGAGCGTCCTCAGCCAAGGAAATAAAAAGCCACAAAATAG
  AAAAGAAAAAGAAGAGAAGGTTGAAAAGAGAAGTAACAGTGACAGCAAAGAAAACCGGGA
  AACAAAATTAAATGGTCCTGGTGAAAACGTCAGTGAGGATGAGGCTCAGTCAAGTAATCA
  ACGTAAGAGAGCTAATAAGCACAAGTGGGTACCACTCCACTTAGATGTTGTAAGATCAGA
  GAGTCAAGAAAGACCTGGATCCCGGAACAGCTCAAGATGTCAACCTGAAGCANATAAACC
  CACACATTNACATAGGAGAAATGATACACGAAGTTGGAANGCGNNGATNAGGAAAAAGAG
  ATGTTCCGGATGGACGTTTCCAAGGGGAAAAAGGAGGGTGGGTATATCCCCCGGGGTCCT
  TTTAAGAGTCCAGGGAAAAGCCCCGGGGCCGGGGAAAAGGACCCACGGCCAGGAAAATCC
  CGCCAGGGAACTCTTGTAATTTTCTTTGGGGGTTTAAAAAAAGGGGGGGAAGGGGTTTGT
  CCCCTCTTTTAAAAAAAAAATTTTACCCCCCGTGGGGGGTTTTCTTCATATATATGGCCC
  CCGGGCCCCCCGGTTTTTTCCCGGAGAAAAAAAAACCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032239 unedited
  GACCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGATTTTATTCTTATA
  ATTTTATTAGTATGCATAAATGGTTAATGGACAGGCATTACCAACTTGACTGACCTATCT
  TACCTACCCTGCAGAGAAAGTATATGCTATTTTATCTAACTTACCCAATGCCTTGTGAAC
  CCAATGTTCATAAGCTAGCTAAAACTATCATCTTGGACCCAAGTTGATATCATAAATAAA
  TCTAACTTATATAATCACCCATTATATCTTAACAAAAAATAAATTAAAAACCACTAGCTA
  AAATAATGTCACTCTTCTTCAGCTTTTAAAATGCCTGTCCAAGTTGCTTACTGGGATTAG
  AAGCAGAAGGCTGACAAAGAAACATATGATAAAAATAGTGTGAGACTGTCCATCATCGAT
  GCTTTGTTGATGGGACGTCCTCTCATACTGATGTATCAAAAATACATTTTGAAGAGTAAA
  GGAAGAAATAACCTCATCCAGTTCTTAAATTCCTTACCCCTTAAGTGACCACATTAATAA
  GTCTTATGTCCAAGTGAAACATCATGACAATATCTGAGTTTTACAATGTACACTACACTG
  AAAGGCAAATCGAATAGCAAAGTACTTAAGAATCTGGGAAATGCTACTCAATCCCCTCTT
  TTTCTGCTTTATTCATCTGGACACAAGTACATAANCCCTGGGAACAGAAAACATAATCTT
  GCGGTATTTCCAGAATAATAATAATTAACTTTCCCACCATGAATAAAAGCAGCCCATGCA
  GCCCAGGCCAATTACACAGAAATAGGCAGCTCCTATAAAAAGATAACAGTCCTCTGGTCT
  GTCTCTATTATCGCAAAGGTGTTAATCTCCCTGCAGTGTTGGCCCAACTCCTCCACCAGA
  GTGGGATAGAATTCTGAACAAAGACAGTTGACGCTTCATTTTGCACAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032239
• Insert Size: 2770 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_032239.2, NP_115615.2
• RefSeq Size: 2718 bp
• RefSeq ORF: 1077 bp
• Locus ID: 55132
• UniProt ID: Q659C4
• Cytogenetics: 4q28.2
• Domains: DM15
• Gene Summary: This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]
  Transcript Variant: This variant (3) lacks several exons and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 3 which is much shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.