SOX22 (SOX12) (NM_006943) Human Untagged Clone

CAT#: SC125839

SOX12 (untagged)-Human SRY (sex determining region Y)-box 12 (SOX12)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SOX22
• Synonyms: SOX22
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC125839 sequence for NM_006943 edited (data generated by NextGen Sequencing)
  
  
  ATGGTGCAGCAGCGGGGCGCGAGGGCCAAGCGGGACGGCGGGCCGCCGCCCCCGGGACCCGGGCCGGCCG
  AGGAGGGGGCGCGCGAGCCCGGCTGGTGCAAGACCCCGAGCGGCCACATCAAGAGGCCGATGAACGCATT
  CATGGTGTGGTCGCAGCACGAACGGCGGAAGATCATGGACCAGTGGCCCGACATGCACAACGCCGAGATC
  TCCAAGCGCCTGGGCCGCCGCTGGCAGCTGCTGCAGGACTCGGAGAAGATCCCGTTCGTGCGGGAGGCGG
  AGCGGCTGCGGCTCAAGCACATGGCGGATTACCCGGACTACAAGTACCGGCCGCGCAAAAAGAGCAAGGG
  GGCGCCCGCCAAGGCGCGGCCCCGCCCCCCCGGTGGTAGCGGTGGCGGCAGCCGGCTCAAGCCCGGGCCG
  CAGCTGCCTGGCCGCGGGGGCCGCCGAGCAGCGGGAGGGCCTTTGGGGGGCGGGGCGGCGGCGCCCGAGG
  ACGACGATGAAGACGACGACGAGGAGCTGCTGGAAGTGCGCCTGGTCGAGACCCCGGGGCGGGAGCTGTG
  GAGGATGGTCCCGGCGGGACGGGCCGCTCGGGGACAAGCGGAGCGCGCCCAAGGGCCGTCGGGCGAGGGG
  GCGGCCGCCGCCGCCGCCGCCTCCCCGACACCGTCGGAGGACGAGGAGCCGGAGGAAGAGGAGGAGGAGG
  CGGCAGCGGCTGAGGAAGGTGAAGAGGAGACGGTGGCGTCGGGGGAGGAGTCGCTGGGCTTTCTGTCCAG
  GCTGCCCCCTGGCCCGGCCGGCCTGGACTGCAGCGCCCTGGATCGCGACCCGGACCTGCAGCCTCCCTCG
  GGCACGTCGCACTTCGAGTTCCCGGACTACTGCACCCCCGAGGTTACCGAGATGATCGCGGGGGACTGGC
  GCCCGTCTAGCATCGCAGACCTGGTTTTCACCTACTGA
  
  Clone variation with respect to NM_006943.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006943 unedited
  GGGGCGTCACATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCGGGC
  GGGGAGCGGCGCGCGCGGGCCGCGGCGGAGCCAGAGGCTGCAGGAAGAGCCCGCGGGGGC
  CCGGAGGGTGCGATTCCTCGGCCCCCGCAAAACAATGTGTGTTGTGAGCCAGGACGCAAC
  TTGCCGGAGGCGGCGGGGGCGCGCCGAGCCCGCCTGAGACCGCGCTGACCTCCTCCCCCA
  CCCCCAGCCGCGGAGGATGCGGACGGCCCCCGGCGGCGTCTAGCGGCCCCGGGCCCAGGC
  GCGATGGTGCAGCAGCGGGGCGCGAGGGCCAAGCGGGACGGCGGGCCGCCGCCCCCGGGA
  CCCGGGCCGGCCGAGGAGGGGGCGCGCGAGCCCGGCTGGTGCAAGACCCCGAGCGGCCAC
  ATCAAGAGGCCGATGAACGCATTCATGGTGTGGTCGCAGCACGAACGGCGGAAGATCATG
  GACCAGTGGCCCGACATGCACAACGCCGAGATCTCCAAGCGCCTGGGCCGCCGCTGGCAG
  CTGCTGCAGGACTCGGAGAAGATCCCGTTCGTGCGGGAGGCGGAGCGGCTGCGGCTCAAG
  CACATGGCGGATTACCCGGACTACAAGTACCGGCCGCGCANAAAGACAAGGGGGCGCCCG
  CCAAGGCGCGGCCCCGCCCCCCCGGTGGTAGCGGTGGCGGCAGCCGGCTCAAGCCCGGGC
  CGCAACTGCCTGGCCGCGGGGCCGCCCGACACGGGAGGCCTTTGGGGGGCGGTGCGGCGG
  CCCCTGTGGCCACGATTAAACGACAATAGGAACTGCTGAAATGCCCCTGGTCAAACCCCG
  GGCCGGGACTGTGAAGAATGTCCCAGCCAAACCC
  
• Restriction Sites: Please inquire
• ACCN: NM_006943
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006943.2, NP_008874.2
• RefSeq Size: 4658 bp
• RefSeq ORF: 948 bp
• Locus ID: 6666
• UniProt ID: O15370
• Cytogenetics: 20p13
• Protein Families: ES Cell Differentiation/IPS, Transcription Factors
• Gene Summary: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]