GM CSF Receptor alpha (CSF2RA) (NM_172249) Human Untagged Clone

CAT#: SC124940

CSF2RA (untagged)-Human colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GM CSF Receptor alpha
• Synonyms: alphaGMR; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMCSFR-alpha; GMR; GMR-alpha; SMDP4
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_172249, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTTCTCCTGGTGACAAGCCTTCTGCTCTGTGAGTTACCACACCCAGCATTCCTCCTGATCCCAGAGA
  AATCGGATCTGCGAACAGTGGCACCAGCCTCTAGTCTCAATGTGAGGTTTGACTCCAGGACGATGAATTT
  AAGCTGGGACTGCCAAGAAAACACAACCTTCAGCAAGTGTTTCTTAACTGACAAGAAGAACAGAGTCGTG
  GAACCCAGGCTCAGTAACAACGAATGTTCGTGCACATTTCGTGAAATTTGTCTGCATGAAGGAGTCACAT
  TTGAGGTTCACGTGAATACTAGTCAAAGAGGATTTCAACAGAAACTGCTTTATCCAAATTCAGGAAGGGA
  GGGTACCGCTGCTCAGAATTTCTCCTGTTTCATCTACAATGCGGATTTAATGAACTGTACCTGGGCGAGG
  GGTCCGACGGCCCCCCGTGACGTCCAGTATTTTTTGTACATACGAAACTCAAAGAGAAGGAGGGAGATCC
  GGTGTCCTTATTACATACAAGACTCAGGAACCCATGTGGGATGTCACCTGGATAACCTGTCAGGATTAAC
  GTCTCGCAATTACTTTCTGGTTAACGGAACCAGCCGAGAAATTGGCATCCAATTCTTTGATTCACTTTTG
  GACACAAAGAAAATAGGTTCCTTAGGATACAGCGGCTGTTCCCGCCAGTTCCACAGATCAAAGACAAACT
  GA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172249 unedited
  GCCCCGGGCCACCAACCCCCTCCCCCCCCNGGTTCAAATTTGNATACGATTACTATAGGC
  GGCCGCGNAATTCGCACCANAAAAAAAGCGGTGGAAGGAGAGGAAGCGGATGCCGTGGGG
  TTTACAGCAGGAAAATCCGTGGAGACAGCAGATCCGAGAAGCGGCGATGTTTGCGTAGAA
  CCCTGTACGTGCTTCCTTCGGCCTGTCGCTCTTCCCTTCTCTCTGACCAGCACCATGCTT
  CTCCTGGTGACAAGCCTTCTGCTCTGTGAGTTACCACACCCAGCATTCCTCCTGATCCCA
  GAGAAATCGGATCTGCGAACAGTGGCACCAGCCTCTAGTCTCAATGTGAGGTTTGACTCC
  AGGACGATGAATTTAAGCTGGGACTGCCAAGAAAACACAACCTTCAGCAAGTGTTTCTTA
  ACTGACAAGAAGAACAGAGTCGTGGAACCCAGGCTCAGTAACAACGAATGTTCGTGCACA
  TTTCGTGAAATTTGTCTGCATGAAGGAGTCACATTTGAGGTTCACGTGAATACTAGTCAA
  AGAGGATTTCAACAGAAACTGCTTTATCCAAATTCAGGAAGGGAGGGTACCGCTGCTCAG
  AATTTCTCCTGTTTCATCTACCAATGCGATTTAATGAACTGTACCTGGGCGAAGGGTCCG
  ACGGCCCCCCGTGACGTCCAGTATTTTTTGTACATACGAAACTCANAGAGAAGGAGGGAG
  ATCCGGTGTCCTTATTTACATACAGACTCANGAACCCATGNTGGATGTCACCTGGATAAC
  CTGTCAGGATTAACGTCTCGCATTACTTTCTGGNTACGGNACAGCCGAGAAATGGCACTC
  CATCTTTGATTCACTTTTGACCCAAGAAAATAGACGATTCACCCTTCCAGCATGTCACGT
  ACGTGGCACCGACGCACTGCCGTACGTGGAAACGCCCCAGACTATAAAGCTGCGTACTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_172249
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_172249.1, NP_758452.1
• RefSeq Size: 1458 bp
• RefSeq ORF: 1458 bp
• Locus ID: 1438
• UniProt ID: P15509
• Cytogenetics: X;Y
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer
• Gene Summary: The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (6) lacks four coding exons, which causes a frameshift, compared to variant 1. The resulting isoform (e), which is likely soluble, is shorter and has a distinct C-terminus compared to isoform a.