CLNS1A (NM_001293) Human Untagged Clone

CAT#: SC119328

CLNS1A (untagged)-Human chloride channel, nucleotide-sensitive, 1A (CLNS1A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLNS1A
• Synonyms: CLCI; CLNS1B; ICln
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119328 sequence for NM_001293 edited (data generated by NextGen Sequencing)
  ATGAGCTTCCTCAAAAGTTTCCCGCCGCCTGGGCCAGCGGAGGGGCTCCTGCGGCAGCAG
  CCAGACACTGAGGCTGTGCTGAACGGGAAGGGCCTCGGCACTGGTACCCTTTACATCGCT
  GAGAGCCGCCTGTCTTGGTTAGATGGCTCTGGATTAGGATTCTCACTGGAATACCCCACC
  ATTAGTTTACATGCATTATCCAGGGACCGAAGTGACTGTCTAGGAGAGCATTTGTATGTT
  ATGGTGAATGCCAAATTTGANNAAGAATCAAAAGAACCTGTTGCTGATGAAGAAGAGGAA
  GACAGTGATGATGATGTTGAACCTATTACTGAATTTAGATTTGTGCCTAGTGATAAATCA
  GCGTTGGAGGCAATGTTCACTGCAATGTGCGAATGCCAGGCCTTGCATCCAGATCCTGAG
  GATGAGGATTCAGATGACTACGATGGAGAAGAATATGATGTGGAAGCACATGAACAAGGA
  CAGGGGGACATCCCTACATTTTACACCTATGAAGAAGGATTATCCCATCTAACAGCAGAA
  GGCCAAGCCACACTGGAGAGATTAGAAGGAATGCTTTCTCAGTCTGTGAGCAGCCAGTAT
  AATATGGCTGGGGTCAGGACAGAAGATTCAATAAGAGATTATGAAGATGGGATGGAGGTG
  GATACCACACCAACAGTTGCTGGACAGTTTGAGGATGCAGATGTTGATCACTGA
  
  Clone variation with respect to NM_001293.2
  261 a=>n;262 g=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001293 unedited
  TACGACTCCTATAGGCGGCCGCGACTTCGGCACGAGGGTGTGGTGCACGCATTGCTGTGC
  TCCAACTCCCTCAGGCCTGTGTTGCCGCACTCTGCTGCTATGAGCTTCCTCAAAAGTTTC
  CCGCCGCCTGGGCCAGCGGAGGGGCTCCTGCGGCAGCAGCCAGACACTGAGGCTGTGCTG
  AACGGGAAGGGCCTCGGCACTGGTACCCTTTACATCGCTGAGAGCCGCCTGTCTTGGTTA
  GATGGCTCTGGATTAGGATTCTCACTGGAATACCCCACCATTAGTTTACATGCATTATCC
  AGGGACCGAAGTGACTGTCTAGGAGAGCATTTGTATGTTATGGTGAATGCCAAATTTGAA
  GAATCAAAAGAACCTGTTGCTGATGAAGAAGAGGAAGACAGTGATGATGATGTTGAACCT
  ATTACTGAATTTAGATTTGTGCCTAGTGATAAATCAGCGTTGGAGGCAATGTTCACTGCA
  ATGTGCGAATGCCAGGCCTTGCATCCAGATCCTGAGGATGAGGATTCAGATGACTACGAT
  GGAGAAGAATATGATGTGGAAGCACATGAACAAGGACAGGGGGACATCCCTACATTNTAC
  ACCTATGAAGAAAGATTATCCCATCTAACAGCAGAAAGCCAAGCCACACTGGAGAGATTA
  GAAGGAATGCTTTCTCAGTCTGTGAGCAGCCAGTATAATATGGGCTGGNGGTCANGACAG
  AAGATTCANNTAGAGATATGAAGATGGGGATGGAGTGGGATACCACACCAACAGTGCTGG
  AAAGTTTGAGATGCAAATGTTGATACTGAAATGATNNATGCAGTTAGATCTGCTCCTAGG
  TAGAAAAACTGGGGGCTCTTCTTTGGAGGAGTAAAGGAGATTTTTTCTTTTCAAACAACC
  AACCATTTTTTGGAACAACTCTGAAAACAATGGCCACGAGAAGAAATGACCTTAATGGAA
  ACTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001293 unedited
  NNNTTTAGCTTGCCCGCGGCCGCTATCTAAGATCGGTTTTTTTTTTTTTTTTTTAATATA
  CAAAACCTACGCTTATTTGTTAAGCTATTACAAAAACAAAACAATTACCATTTGAAGTAC
  TTTGAGGACTTCATCCCACCACTCACTTGTTCTGTTACAGAAACTAACCTAAAAGGCTGG
  AAATTAAAGGATACAACCTAAGAGGCTATAACAGCAGACTGGTAAAACATGGCGAAAGGA
  GCTCTCTCTTTCCCCCGCAGTCTACCAAGCTCCTGCGCATTTTCACCACATAGATCTGCT
  AGCTTACAAATGATGCACACAGTCAAGGTAGGAATTATAGGCCTACTCAGAGGGTACCCA
  CACACAGAAAGTTCTAGGGTAAATAGTAAACTACAAATACCCTCTTGGTTAAGCTAATTC
  ATCACGTTCCTAAAGGTCATATTATCTATCTTCTGCTGGTGACAACTTGCTGTCTCATCA
  TAGTCCGCCTCAAGAAAACAACCGGCCTACGCTCGGCTCTGCAAAACGAAACAGACTTTC
  ATCAACTCCACTCCATAGTGGAACAGGCACCAAGTTTCTCTCCTACCCTCACGAGCCAGA
  CCCTTAAACTTCGCCATAACACCACTTTCACTGTCCCAAATCCTGCATCCCTAAATTGTC
  CACAAACTGCTGGTTGTGGTATACCCTCTCCATCCCCCCTTGCATAATACTCTCATAGCA
  ACCTTTCGTTCCCGCCCTATCCCTATTCCTACTTGCCTCGCCCACAACACTGCCACAAGC
  CCCTCCTCCTACATTTCCCATATGAGGCTTTGCCCCCCCCGGTTGTAAGAAGCGGAAAAT
  ACCTCTCTCTCTAGCGTCTCACAAGGTTTGCATGCCTCCCCCTGTCTCTCGATTTATGTC
  GCTTCCACACCCATACTCTTCTCTAATTCAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001293
• Insert Size: 1330 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001293.1, NP_001284.1
• RefSeq Size: 1368 bp
• RefSeq ORF: 714 bp
• Locus ID: 1207
• UniProt ID: P54105
• Cytogenetics: 11q14.1
• Domains: ICln_channel
• Protein Families: Ion Channels: Other
• Gene Summary: This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).