BNIP3L (NM_004331) Human Untagged Clone

CAT#: SC117435

BNIP3L (untagged)-Human BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BNIP3L
• Synonyms: BNIP3a; NIX
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004331 edited
  GAATTCGGCACGAGGCGGACTCGGCTTGTTGTGTTGCTGCCTGAGTGCCGGAGACGGTCC
  TGCTGCTGCCGCAGTCCTGCCAGCTGTCCGACGATGTCGTCCCACCTAGTCGAGCCGCCG
  CCGCCCCTGCACAACAACAACAACAACTGCGAGGAAAATGAGCAGTCTCTGCCCCCGCCG
  GCCGGCCTCAACAGTTCCTGGGTGGAGCTACCCATGAACAGCAGCAATGGCAATGATAAT
  GGCAATGGGAAAAATGGGGGGCTGGAACACGTACCATCCTCATCCTCCATCCACAATGGA
  GACATGGAGAAGATTCTTTTGGATGCACAACATGAATCAGGACAGAGTAGTTCCAGAGGC
  AGTTCTCACTGTGACAGCCCTTCGCCACAAGAAGATGGGCAGATCATGTTTGATGTGGAA
  ATGCACACCAGCAGGGACCATAGCTCTCAGTCAGAAGAAGAAGTTGTAGAAGGAGAGAAG
  GAAGTCGAGGCTTTGAAGAAAAGTGCGGACTGGGTATCAGACTGGTCCAGTAGACCCGAA
  AACATTCCACCCAAGGAGTTCCACTTCAGACACCCTAAACGTTCTGTGTCTTTAAGCATG
  AGGAAAAGTGGAGCCATGAAGAAAGGGGGTATTTTCTCCGCAGAATTTCTGAAGGTGTTC
  ATTCCATCTCTCTTCCTTTCTCATGTTTTGGCTTTGGGGCTAGGCATCTATATTGGAAAG
  CGACTGAGCACACCCTCTGCCAGCACCTACTGAGGGAAAGGAAAAGCCCCTGGAAATGCG
  TGTGACCTGTGAAGTGGTGTATTGTCACAGTAGCTTATTTGAACTTGAGACCATTGTAAG
  CATGACCCAACCTACCACCCTGTTTTTACATATCCAATTCCAGTAACTCTCAAATTCAAT
  ATTTTATTCAAACTCTGTTGAGGCATTTTACTAACCTTATACCCTTTTTGGCCTGAAGAC
  ATTTTAGAATTTCCTAACAGAGTTTACTGTTGTTTAGAAATTTGCAAGGGCTTCTTTTCC
  GCAAATGCCACCAGCAGATTATAATTTTGTCAGCAATGCTATTATCTCTAATTAGTGCCA
  CCAGACTAGACCTGTATCATTCATGGTATAAATTTTACTCTTGCAACATAACTACCATCT
  CTCTCTTAAAACGAGATCAGGTTAGCAAATGATGTAAAAGAAGCTTTATTGTCTAGTTGT
  TTTTTTTCCCCCAAGACAAAGGCAAGTTTCCCTAAGTTTGAGTTGATAGTTATTAAAAAG
  AAAACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004331 unedited
  GTTTTTCATTTGTATACGACTCATATAGGCGGCACGCGAATTCGCACGAGGCGGACTCGG
  CTTGTTGTGTTGCTGCCTGAGTGCCGGAGACGGTCCTGCTGCTGCCGCAGTCCTGCCAGC
  TGTCCGACGATGTCGTCCCACCTAGTCGAGCCGCCGCCGCCCCTGCACAACAACAACAAC
  AACTGCGAGGAAAATGAGCAGTCTCTGCCCCCGCCGGCCGGCCTCAACAGTTCCTGGGTG
  GAGCTACCCATGAACAGCAGCAATGGCAATGATAATGGCAATGGGAAAAATGGGGGGCTG
  GAACACGTACCATCCTCATCCTCCATCCACAATGGAGACATGGAGAAGATTCTTTTGGAT
  GCACAACATGAATCAGGACAGAGTAGTTCCAGAGGCAGTTCTCACTGTGACAGCCCTTCG
  CCACAAGAAGATGGGCAGATCATGTTTGATGTGGAAATGCACACCAGCAGGGACCATAGC
  TCTCAGTCAGAAGAAGAAGTTGTAGAAGGAGAGAAGGAAGTCGAGGCTTTGAAGAAAAGT
  GCGGACTGGGTATCAGACTGGTCCAGTAGACCCGAAAACATTCCACCCAAGGAGTTCCAC
  TTCAGACACCCTAAACGTTCTGTGTCTTTAAGCATGAGGAAAAGTGGAGCCATGAAGAAA
  GGGGGTATTTTCTCCGCAGAATTTCTGAAGGTGTTCATTCCATCTCTCTTCCTTTCTCAT
  GTTTTGGCTNTGGGGCTAGGCATCTATATTGGATAGCGACTGAGCACACCCTCTGCCAGC
  ACCTACTGAGGGATATGAAAAGCCCCTGGAAATGCGTGTGACCTGTGAAGTGGTGTATTG
  TCACAGTAGCCTATTTGAACTTGAGACCATTGTAGCATGACCCANCCTACCACCCTGTTT
  TTACATATCCAATTGCCAGTACTCTCAAATTCATATTTTATTCAACTCTGGTGAGCATTT
  TACA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004331 unedited
  TTTGGCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGGTTTCTTTTTAA
  TAACTATCAACTCAAACTTAGGGGAAACTTGCCTTTGTCTTGGGGGAAAAAAAACAACTA
  GACAATAAAGCTTCTTTTACATCATTTGCTAACCTGATCTCGTTTTAAGAGAGAGATGGT
  AGTTATGTTGCAAGAGTAAAATTTATACCATGAATGATACAGGTCTAGTCTGGTGGCACT
  AATTAGAGATAATAGCATTGCTGACAAAATTATAATCTGCTGGTGGCATTTGCGGAAAAG
  AAGCCCTTGCAAATTTCTAAACAACAGTAAACTCTGTTAGGAAATTCTAAAATGTCTTCA
  GGCCAAAAAGGGTATAAGGTTAGTAAAATGCCTCAACAGAGTTTGAATAAAATATTGAAT
  TTGAGAGTTACTGGAATTGGATATGTAAAAACAGGGTGGTAGGTTGGGTCATGCTTACAA
  TGGTCTCAAGTTCAAATAAGCTACTGTGACAATACACCACTTCACAGGTCACACGCATTT
  CCAGGGGCTTTTCCTTTCCCTCAGTAGGTGCTGGCAGAGGGTGTGCTCAGTCGCTTTCCA
  ATATAGATGCCTAGCCCCAAAGCCAAAACATGAGAAAGGAAGAGAGATGGGATGAACACC
  TTCAGAAATTCTGCGGAGAAAATACCCCCTTTCTTCATGGCTCCACTTTTCCTCATGCTT
  AAAGCACAGAACGTTTAGGGTGTCTGAAGTGGAACTCTTGGNTGGNATGTTTCGGNTCTA
  CTGGNACAGTCTGATACCCATCCGCACTTTCTTCAAGNCTNGACTTCCTTCTCTCTTCTA
  CACTNNTNTTNTGACTGAAGCTATGGCCCTGCCTGGGGGCATTTCCATAAACATGACTGG
  CATCTTCTGGGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004331
• Insert Size: 1270 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004331.2, NP_004322.1
• RefSeq Size: 3505 bp
• RefSeq ORF: 660 bp
• Locus ID: 665
• UniProt ID: O60238
• Cytogenetics: 8p21.2
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]