CFHL2 (CFHR2) (NM_005666) Human Untagged Clone

CAT#: SC116582

CFHR2 (untagged)-Human complement factor H-related 2 (CFHR2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CFHL2
• Synonyms: CFHL2; FHR2; HFL3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005666, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGCTCCTGGTCAGTGTAATTCTAATCTCACGGATATCCTCTGTTGGGGGAGAAGCAATGTTCTGTG
  ATTTTCCAAAAATAAACCATGGAATTCTATATGATGAAGAAAAATATAAGCCATTTTCCCAAGTTCCTAC
  AGGGGAAGTTTTCTATTACTCCTGTGAATATAATTTTGTGTCTCCTTCAAAATCCTTTTGGACTCGCATA
  ACGTGCGCAGAAGAAGGATGGTCACCAACACCAAAGTGTCTCAGACTGTGTTTCTTTCCTTTTGTGGAAA
  ATGGTCATTCTGAATCTTCAGGACAAACACATCTGGAAGGTGATACTGTACAAATTATTTGCAACACAGG
  ATACAGACTTCAAAACAATGAGAACAACATTTCATGTGTAGAACGGGGCTGGTCCACTCCTCCCAAATGC
  AGGTCCACTATTTCTGCAGAAAAATGTGGGCCCCCTCCACCTATTGACAATGGAGACATTACTTCATTCC
  TGTTGTCAGTATATGCTCCAGGTTCATCAGTTGAGTACCAGTGCCAGAACTTGTATCAACTTGAGGGTAA
  CAATCAAATAACATGTAGAAACGGACAATGGTCAGAACCACCAAAATGCTTAGATCCATGTGTAATATCA
  CAAGAAATTATGGAAAAATATAACATAAAATTAAAGTGGACAAACCAACAAAAGCTTTATTCAAGAACAG
  GTGACATAGTTGAATTTGTTTGTAAATCTGGATATCATCCAACAAAATCTCATTCATTTCGAGCAATGTG
  TCAGAATGGGAAACTGGTATATCCCAGTTGTGAAGAAAAATAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005666 unedited
  GGTTCGCATTTGTATACGACTCCTATAGGCGGCCCGCGATTCGGCACGAGCACTGAAGTA
  TTTTTAGTTATATAAGATTGGAACTACCAAGCATGTGGCTCCTGGTCAGTGTAATTCTAA
  TCTCACGGATATCCTCTGTTGGGGGAGAAGAGTCTTGCTCTGTCGCCCCCAGGATGGTGT
  TTAGTGGCATGATCTCGGCTCACTGCAACATACCCCTCCTGGGTTCAAGTGATTCTTCTG
  CCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCGCACCACCACACCTGGCTAATTTTTG
  TATTTTTAGTAGAGATGGGCTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCT
  CAAGTGATCCACCTACCTCAGCCTCCCAAAGTGCTGGGATTACAGCAATGTTCTGTGATT
  TTCCAAAAATAAACCATGGAATTCTATATGATGAAGAAAAATATAAGCCATTTTCCCAAG
  TTCCTACAGGGGAAGTTTTCTATTACTCCTGTGAATATAATTTTGTGTCTCCTTCAAAAT
  CCTTTTGGACTCGCATAACGTGCGCAGAAGAAGGATGGTCACCAACACCAAAGTGTCTCA
  GACTGTGTTTCTTTCCTTTTGTGGAAAATGGTCATTCTGAATCTTCAGGACAAACACATC
  TGGAAGGTGATACTGTACAAATTATTTGCAACACAGGATACAGACTTCAAAACAATGAGA
  ACAACATTTCATGTGTAGAACGGNGCTGGTCCACTCCTCCCCAATGCAGTCCACTATTTC
  TGCAGAAAAATGTGGGCCCCCTCCACCTATTNGACATGGAGACATTACTTCATTCCTGTT
  GTCAGTATATGCTTCCAGGTCATCAGTTGAGTACCAGTGCCAGAACTTGTATCAACTTGA
  GGGNTACATCAAATACATGTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005666 unedited
  NNNTTTTNGGGGGGNNNNNAACGGGNNNTTTANNNNNNNNNNTTTTAATNTGNNACGCGG
  NCCGCATACNANGATCGNGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCATTTTCA
  CAAATCAACACAAAACTTTATTTATGAATAAAAATGAGTAAAACAGTACTTGGAAAAATG
  AAATTGAAAACAAATATAATAGTAAATTCAGAAAAAGGGGGGCATTTTACTAATAGTAAT
  GCCATTGATTCTATTTTTCTTCACAACTGGGATATACCAGTTTCCCATTCTGACACATTG
  CTCGAAATGAATGAGATTTTGTTGGATGATATCCAGATTTACAAACAAATTCAACTATGT
  CACCTGTTCTTTGATAAAGNCTTTGTTGGTTNGCCCACTTTAATTNTATGTATATTTTTC
  CATAAATTNCTGGGGAAATACACATGGATCTAAGCATTTTGGTGGGTCTGACCATTGNCC
  GTTCTACATGGTATTNGATTGGTACCCTCAAGTTGAAACAAGTTCTGGCACTGTTACTTA
  CTGATGAACCTGGAGCTATACTGACACCAGGAATGAAGAATGGCTCCATTGCAATAAGGG
  GAAGGGGCCCCATTTTTTTGCCAAAATAGGGGACCGGCTTTGGGAAGGAATGGACCACCC
  CGGTTTTAACATGAAAAAAGGGGTTCCCATTGGTTGAAAATCTTGATTCTGGGGGTGCAA
  AAATTTGGAACGGTTACACCTACAAAAGGGGTTTGGCCTGAAAATTCCAATGGACCTTTT
  TCCCAAAAGGAAAAAAACCAAACCTGAACACTTTGGGGTTGGGGACCATCCTTTTTTTGG
  CACCGTTTGAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005666
• Insert Size: 1280 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005666.2, NP_005657.1
• RefSeq Size: 1043 bp
• RefSeq ORF: 813 bp
• Locus ID: 3080
• UniProt ID: P36980
• Cytogenetics: 1q31.3
• Domains: CCP
• Protein Families: Secreted Protein
• Gene Summary: This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.