IL1RAPL1 (NM_014271) Human Untagged Clone

CAT#: SC115085

IL1RAPL1 (untagged)-Human interleukin 1 receptor accessory protein-like 1 (IL1RAPL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL1RAPL1
• Synonyms: IL-1-RAPL-1; IL-1RAPL-1; IL1R8; IL1RAPL; IL1RAPL-1; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014271, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAAGCTCCGATTCCACACTTGATTCTCTTATACGCTACTTTTACTCAGAGTTTGAAGGTTGTGACCA
  AAAGAGGCTCCGCCGATGGATGCACTGACTGGTCTATCGATATCAAGAAATATCAAGTTTTGGTGGGAGA
  GCCTGTTCGAATCAAATGTGCACTCTTTTATGGTTATATCAGAACAAATTACTCCCTTGCCCAAAGTGCT
  GGACTCAGTTTGATGTGGTACAAAAGTTCTGGTCCTGGAGACTTTGAAGAGCCAATAGCCTTTGACGGAA
  GTAGAATGAGCAAAGAAGAAGACTCCATTTGGTTCCGGCCAACATTGCTACAGGACAGTGGTCTCTACGC
  CTGTGTCATCAGAAACTCCACTTACTGTATGAAAGTATCCATCTCACTGACAGTGGGTGAAAATGACACT
  GGACTCTGCTATAATTCCAAGATGAAGTATTTTGAAAAAGCTGAACTTAGCAAAAGCAAGGAAATTTCAT
  GCCGTGACATAGAGGATTTTCTACTGCCAACCAGAGAACCTGAAATCCTTTGGTACAAGGAATGCAGGAC
  AAAAACATGGAGGCCAAGTATTGTATTCAAAAGAGATACTCTGCTTATAAGAGAAGTCAGAGAAGATGAC
  ATTGGAAATTATACCTGTGAATTAAAATATGGAGGCTTTGTTGTGAGAAGAACTACTGAATTAACTGTTA
  CAGCCCCTCTGACTGATAAGCCACCCAAGCTTTTGTATCCTATGGAAAGTAAACTGACAATTCAGGAGAC
  CCAGCTGGGTGACTCTGCTAATCTAACCTGCAGAGCTTTCTTTGGGTACAGCGGAGATGTCAGTCCTTTA
  ATTTACTGGATGAAAGGAGAAAAATTTATTGAAGATCTGGATGAAAATCGAGTTTGGGAAAGTGACATTA
  GAATTCTTAAGGAGCATCTTGGGGAACAGGAAGTTTCCATCTCATTAATTGTGGACTCTGTGGAAGAAGG
  TGACTTGGGAAATTACTCCTGTTATGTTGAAAATGGAAATGGACGTCGACACGCCAGCGTTCTCCTTCAT
  AAACGAGAGCTAATGTACACAGTGGAACTTGCTGGAGGCCTTGGTGCTATACTCTTGCTGCTTGTATGTT
  TGGTGACCATCTACAAGTGTTACAAGATAGAAATCATGCTCTTCTACAGGAATCATTTTGGAGCTGAAGA
  GCTCGATGGAGACAATAAAGATTATGATGCATACTTATCATACACCAAAGTGGATCCTGACCAGTGGAAT
  CAAGAGACTGGGGAAGAAGAACGTTTTGCCCTTGAAATCCTACCTGATATGCTTGAAAAGCATTATGGAT
  ATAAGTTGTTTATACCAGATAGAGATTTAATCCCAACTGGAACATACATTGAAGATGTGGCAAGATGTGT
  AGATCAAAGCAAGCGGCTGATTATTGTCATGACCCCAAATTACGTAGTTAGAAGGGGCTGGAGCATCTTT
  GAGCTGGAAACCAGACTTCGAAATATGCTTGTGACTGGAGAAATTAAAGTGATTCTAATTGAATGCAGTG
  AACTGAGAGGAATTATGAACTACCAGGAGGTGGAGGCCCTGAAGCACACCATCAAGCTCCTGACGGTCAT
  TAAATGGCATGGACCAAAATGCAACAAGTTGAACTCCAAGTTCTGGAAACGTTTACAGTATGAAATGCCT
  TTTAAGAGGATAGAACCCATTACACATGAGCAGGCTTTAGATGTCAGTGAGCAAGGGCCTTTTGGGGAGC
  TGCAGACTGTCTCGGCCATTTCCATGGCCGCGGCCACCTCCACAGCTCTAGCCACTGCCCATCCAGATCT
  CCGTTCTACCTTTCACAACACGTACCATTCACAAATGCGTCAGAAACACTACTACCGAAGCTATGAGTAC
  GACGTACCTCCTACCGGCACCCTGCCTCTTACCTCCATAGGCAATCAGCATACCTACTGTAACATCCCTA
  TGACACTCATCAACGGGCAGCGGCCACAGACAAAATCGAGCAGGGAGCAGAATCCAGATGAGGCCCACAC
  AAACAGTGCCATCCTGCCGCTGTTGCCAAGGGAGACCAGTATATCCAGTGTGATATGGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014271 unedited
  TACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGTGGAATTATCTGCTTTTATGG
  TGAACTTGGCATTTGTGAATGGGAATCTTGTTCACAATATTAATTGCTAGCAAAAACAAG
  AAAAAGAACACAGGAGTAAAACGTGGATTTTTCTGAATACGCATTGTGATGACCAGCAAT
  TACCTTACCGACTAATATCCAGAGGAGAATAATTTGGAAGACTGTTGTGGGGAACGGCCT
  TTAAGAGCTGGAAGATGAAAGCTCCGATTCCACACTTGATTCTCTTATACGCTACTTTTA
  CTCAGAGTTTGAAGGTTGTGACCAAAAGAGGCTCCGCCGATGGATGCACTGACTGGTCTA
  TCGATATCAAGAAATATCAAGTTTTGGTGGGAGAGCCTGTTCGAATCAAATGTGCACTCT
  TTTATGGTTATATCAGAACAAATTACTCCCTTGCCCAAAGTGCTGGACTCAGTTTGATGT
  GGTACAAAAGTTCTGGTCCTGGAGACTTTGAAGAGCCAATAGCCTTTGACGGAAGTAGAA
  TGAGCAAAGAAGAAGACTCCATTTGGTTCCGGCCAACATTGCTACAGGACAGTGGTCTCT
  ACGCCTGTGTCATCAGAAACTCCACTTACTGTATGANAGTATCCATCTCACTGACAGTGG
  GTGAAAATGACACTGGACTCTGCTATAATTCCAAGATGAAGTATTTTGAAAAAGCTGAAC
  TTAGCANAAGCAAGGAAATTTCATGCCGTGACATAGAGGATTTTCTACTGGCCAACCAGA
  GACCTNGNAATNNCTTTGGGTACAGGGAATGCANNGACANAAACATGGNAGGCCCAAGTA
  TTGTATTCAAAANGAGATACTCTGCTTATNAGAGAAGTCAGAGAAGATGACATTGGAANA
  TATACCTGTGAATTAATATGGAGGGGCTTGTGTGAGAGAACTACTGATNACTGTTCAGNC
  CTCTGACTGATAGCACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014271 unedited
  TTTATGGACCCGCGGCCGCAATCTAGNGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTCCC
  CCGAAGGCAATGCTGGCATTTGTTGCACTGTTCTCTGAAGGCCGACGTGGCCCAGTTGAT
  GCTAGGCAGAACCCGAGAAAGAATCCGGTGCTCCTTGTCCCATCGGATAGATTTGTCCAA
  GCACCCCAAGGAAATGTTAAAAGCAAAGTAAAATTTTAAAAAAGGAAATAAAATAAAAAC
  CCATTCTAAAACTAAACTAATGAAGCAAAAAAAGGGTTTTCTATCTACACATCAGTCTCT
  TCTTTAAAAAAAATGTAAATTTACAAATTCCAACGACATATAAAACAAAGTCAAAAAATG
  TAATGGTAAAAGACATGGTAAAACAGGGAGACACTGATGCTACAAAGAAATTCCAAAAAC
  ATATGTACAAGACCCTGTTTTTCTCGTGTCTAGAGATTCTATGCATGTTTTTTACCGCAA
  CAGTCGAGGATTAGTTCCAGCCCTGGACTGCAGATTCCATCACCCTCCAGGGCGGAATGT
  CCTTGCTTTTTGGCCATTATCCACTGAAATCCTGGCCTCCTTGCCACAGCGCAGGATGGA
  CTGTTTGTGGGGCCTCACCGGGATCTGGTCCCGGCTGATTTGTCTGGGGCCCTGCCCTTT
  GAGAGTGCAAGGGGTGTTCCGAGGGTTCCCTATTCCCTTGGAGTAAAAGCAGGGTCCCCG
  TGGGAGGACCCCCACCCATAACTTCGGGAAGGGGTTTTTAGCCCTTTTGAAAGGGACCTT
  TTGAAAAGGTAAACGGAATTCGTGGGGGAAGGGCTAAACTTGGGGGGGGCCCCGCCCCCT
  GAAAGGGCCAAAAATTTGGATTCCCAAAGGGCCTGTGCCAGGAGGTTAAGCGGGGCGTGG
  ATAGGGGGTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014271
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_014271.2, NP_055086.1
• RefSeq Size: 3624 bp
• RefSeq ORF: 2091 bp
• Locus ID: 11141
• UniProt ID: Q9NZN1
• Cytogenetics: Xp21.3-p21.2
• Domains: TIR, ig, IGc2, IG
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]