RNF41 (NM_005785) Human Untagged Clone

CAT#: SC111140

RNF41 (untagged)-Human ring finger protein 41 (RNF41), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF41
• Synonyms: FLRF; NRDP1; SBBI03
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111140 sequence for NM_005785 edited (data generated by NextGen Sequencing)
  ATGGGGTATGATGTAACCCGTTTCCAGGGGGATGTTGACGAAGATCTTATCTGCCCTATT
  TGCAGTGGAGTCTTGGAGGAGCCAGTACAGGCACCTCATTGTGAACATGCTTTCTGCAAC
  GCCTGCATCACCCAGTGGTTCTCTCAGCAACAGACATGTCCAGTGGACCGTAGTGTTGTG
  ACGGTCGCCCATCTGCGCCCAGTACCTCGGATCATGCGGAACATGTTGTCAAAGCTGCAG
  ATTGCCTGTGACAACGCTGTGTTCGGCTGTAGTGCCGTTGTCCGGCTTGACAACCTCATG
  TCTCACCTCAGCGACTGTGAGCACAACCCGAAGCGGCCTGTGACCTGTGAACAGGGCTGT
  GGCCTGGAGATGCCCAAAGATGAGCTGCCCAACCATAACTGCATTAAGCACCTGCGCTCA
  GTGGTACAGCAGCAGCAGACACGCATCGCAGAGCTGGAGAAGACGTCAGCTGAACACAAA
  CACCAGCTGGCGGAGCAGAAGCGAGACATCCAGCTGCTAAAGGCATACATGCGTGCAATC
  CGCAGTGTCAACCCCAACCTTCAGAACCTGGAGGAGACAATTGAATACAACGAGATCCTA
  GAGTGGGTGAACTCCCTTCAGCCAGCAAGAGTGACCCGCTGGGGAGGGATGATCTCGACT
  CCTGATGCTGTGCTCCAGGCTGTAATCAAGCGCTCCCTGGTGGAGAGTGGCTGTCCTGCT
  TCTATTGTCAACGAGCTGATTGAAAATGCCCACGAGCGTAGCTGGCCCCAGGGTCTGGCC
  ACACTAGAGACTAGACAGATGAACCGACGCTACTATGAGAACTACGTGGCCAAGCGCATC
  CCTGGCAAGCAGGCTGTTGTCGTGATGGCCTGTGAGAACCAGCACATGGGGGATGACATG
  GTGCAAGAGCCAGGCCTTGTCATGATATTTGCGCATGGCGTGGAAGAGATATAA
  
  Clone variation with respect to NM_005785.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005785 unedited
  NGGTCAAAATTTGTATACGACTCCTATAGGCGGCCGCGAATTCGCCGGGGCGGGGCAAAG
  GATCCGTCTGAGGCGGCGACGAGTGAGTACTCCTGATTGTGACATCACATTCATCCCCTG
  GGCGATGGAGCTTGTCACTGGGAAGGAATACTCAGTCGGAGAATAGCCAACAAGATGGGT
  TACTGGGAGAATCTCTTCAGTGGCACTGAGTGGAGGCATCAGGGGGTTGGAGCCTTGTGA
  ACAGGGAACCTGCCCCCCAACACTTGGAAGGACCTGGGTTTCAGTGATGAGACATGGGGT
  ATGATGTAACCCGTTTCCAGGGGGATGTTGACGAAGATCTTATCTGCCCTATTTGCAGTG
  GAGTCTTGGAGGAGCCAGTACAGGCACCTCATTGTGAACATGCTTTCTGCAACGCCTGCA
  TCACCCAGTGGTTCTCTCAGCAACAGACATGTCCAGTGGACCGTAGTGTTGTGACGGTCG
  CCCATCTGCGCCCAGTACCTCGGATCATGCGGAACATGTTGTCAAAGCTGCAGATTGCCT
  GTGACAACGCTGTGTTCGGCTGTAGTGCCGTTGTCCGGCTTGACAACCTCATGTCTCACC
  TCAGCGACTGTGAGCACAACCCGAAGCGGCCTGTGACCTGTGAACAGGGCTGTGGCCTGG
  AGATGCCCAAAGATGAGCTGCCCAACCATAACTGCATTAAGCACCTGCGCTCAGTGGTAC
  AGCAGCAGCAGACACGCATCGCAGAGCTGGAGAAGACGTCAGCTGAACACANACACCAGC
  TGGCGGAGCAGAAGCGAGACATCCAGCTGCTAAAGGCATACATGCGTGCNATCCGCAGTG
  TCAACCCCACCTTCAGACCCTGGNAGAGACATTGATACCACGAGATCCTANAGTGGGTGA
  ACTCCCTTCANCANNCAGATGACCGCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005785 unedited
  TGTACGCGGCCGCATCTATATCGAGTTTTTTTTTTTTTTTTTTTTTAGAGATTGAGTAAA
  AGGTTTATTATTAGTGCAGTCAACACCATGGAACAGCACATACAACACAACCAGCAACCT
  GCAGAGACACTAGTGCAAAGGGTAGGGAAGCCTTTCACTGAGCTTCCTGGCTCCATCTGA
  GGGTAAGGACAGGACAGTATGAGCCTTGGTTAAGGCAGGTAGGGGAAAGGGGAGTGGAAG
  AAATGTAGTAACCAGAGTAAGTATAGCAGCGTTTTCAAATTCCTGAGCACAATGTCCCAG
  AGCTGGAACCCTACTCCCCTCAAGCTTTCCACCCCAATCCCAGTGGAGCCATGATCCAAC
  TACCCAGACCTGCAGCAAGCTAGCCTGGAATAAAATTCTGAGAGGAAGCCATTACATGGT
  GGGGAGGAGCCTTTCTATCTCCAACCACACTCCCACCTCCATATTAAAATAATCACACCT
  ATTATCTCTCCCCTTCTCTTACTCTGCCAGTCACTCTAGGGATCAAGGTATACCCCAGGT
  AACCTGAAATGGAACTGAAGTCCCCAGGGGGGTGTGGGTGAGACACGGCACAGCCTGTAC
  TTAGAGATAAAATTTCTGATTTGCATGGNGAAGCTTAGAACCCAGCTATACAGCTNCAAG
  GAAACTTGGGGAATGGGGGAGTTGCCTTCAAAATGAATACTCTAAATCCAGAGTTTTATG
  ATAAAGCCCTGGAAAGGCTAGGAGGAAATTTTTCCAGAGGGCACAAGCTTCGATGCTGGA
  CTGTCATATCCTTCACAGAAGAGAGAAGCTCCTCATTCAGTTGGGTTACACGAGTTTGGG
  CAAATTCGTAAGTTAGCCGAGACTCCTTGGCTTTTCATATTAAGCCAAGGTGGCTGAAAG
  GAAAATTAAAACACCCCATCCTGTCAACCTTCCAACCCCCATAGGAACTAAAAAAAGTCA
  GTGGATTTTTTCTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005785
• Insert Size: 3220 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005785.2, NP_005776.1
• RefSeq Size: 3286 bp
• RefSeq ORF: 954 bp
• Locus ID: 10193
• UniProt ID: Q9H4P4
• Cytogenetics: 12q13.3
• Domains: RING
• Protein Pathways: Endocytosis
• Gene Summary: This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 3 and 4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.