KLF7 (NM_003709) Human Untagged Clone

CAT#: SC111078

KLF7 (untagged)-Human Kruppel-like factor 7 (ubiquitous) (KLF7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLF7
• Synonyms: UKLF
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003709 edited
  GAATTCGGCACGAGGTGGCAGCTTCGTGTCAGTGAGTTTGCATCCCCCTTCCTGATCCAC
  GAGCTGGAGTGATTAGAGCCCTGGAAGGGAATTGTTACTCCCGTGGAGAAGTCCCCTTTT
  CCTGGCAGTCGTCTGCACTGTACACGCTGGATGCCTCTCTCCATCCACCCCACTCACTCG
  CTCCTCTCTCACCTCCTCTCTCCCTCTCCTGCATTGATTTTTTTTTTTTCCTTTTTAGTT
  GACTGAAACAAAACAAAACAAAAGGGCCACTGGATGTCTGCCTTCTTGGGGGGTGAGCCA
  GACAGACTGACAAACAAACAGCCCCAACTGTGTTCGGGGGAGGGTTTCGCCTCCCGTTTT
  GCCCGGCAGCAGCAGCATGGACGTGTTGGCTAGTTATAGTATATTCCAGGAGCTACAACT
  TGTCCACGACACCGGCTACTTCTCAGCTTTACCATCCCTGGAGGAGACCTGGCAGCAGAC
  ATGCCTTGAATTGGAACGCTACCTACAGACGGAGCCCCGGAGGATCTCAGAGACCTTTGG
  TGAGGACTTGGACTGTTTCCTCCACGCTTCCCCTCCCCCGTGCATTGAGGAAAGCTTCCG
  TCGCTTAGACCCCCTGCTGCTCCCCGTGGAAGCGGCCATCTGTGAGAAGAGCTCGGCAGT
  GGACATCTTGCTCTCTCGGGACAAGTTGCTATCTGAGACCTGCCTCAGCCTCCAGCCGGC
  CAGCTCTTCTCTAGACAGCTACACAGCCGTCAACCAGGCCCAGCTCAACGCAGTGACCTC
  ATTAACGCCCCCATCGTCCCCTGAGCTCAGCCGCCATCTGGTCAAAACCTCACAAACTCT
  CTCTGCCGTGGATGGCACGGTGACGTTGAAACTGGTGGCCAAGAAGGCTGCTCTCAGCTC
  CGTAAAGGTGGGAGGGGTCGCAACAGCTGCAGCAGCCGTGACGGCTGCGGGGGCCGTTAA
  GAGTGGACAGAGCGACAGTGACCAAGGAGGGCTAGGGGCTGAAGCATGTCCCGAAAACAA
  GAAGAGGGTTCACCGCTGTCAGTTTAACGGGTGCCGGAAAGTTTATACAAAAAGCTCCCA
  CTTAAAGGCCCACCAGAGGACTCACACAGGTGAGAAGCCTTATAAGTGCTCATGGGAGGG
  ATGTGAGTGGCGTTTTGCACGAAGCGATGAGCTCACGAGGCACTACAGGAAACACACAGG
  TGCAAAGCCCTTCAAATGCAACCACTGCGACAGGTGTTTTTCCAGGTCTGACCATCTTGC
  CCTCCACATGAAGAGACATATCTAAAAAACCGAAAGGCCAGAGTTGCCATGGCATCGGCT
  AGTGTCTAAAGGAAACGCCATGAGGCAGGGGGCTGGACTTCAGGCGGGGACCCATTGCCT
  CGCAGAAGAAAGTTCTCACTTATAAACCTCTGTACACACACACACACACACACACATATA
  CACACACTCACAGACCCACACACATACACACTGTCATGCACTCAACTATATTTAAAATAT
  ATACGTCTATTCTTTATGCCTTGCCCTAGCCAGATGGAAGAAGATGAAGAAGGAAACCAG
  GTGAACTCAGCAAGGCAGACTGGCTGCTTACTTCAGCACTATTGGAATTATTTCCCGCTG
  TTGCCAATGGAAATCAAAGAAAATGGATGTGACGTCTGTGCAGGTGGACGGCAGTCCGAG
  GGGCTTATTTCACTTGCTTCTCAGTGCAACTTGATAGGAGAATCCAGCATCTTAAAGTTG
  CATATGTGTAGCACTAATGTTTCTTTTTAAATAGTTGGGGGAAAATGACCTAGAAAACCA
  AATTGCAGTTTGGTAGCCAAAATTAACTCTTGGTTTATTTGTCCTTTGTGTGTGAAAAGT
  CCTACTATTCCGTGCGTCAGACTTCCTCACAGAACTGTTGACTGGTTTTGGTTCTTAGTA
  CTATTGAGATCTTTCGCGTCGATCCCAACGGCCTTAGCGGCGGCAGACTGGAATAACACC
  TTACACCTTTCTGGCCTGCATTTCTGTAGACTTCACTCTCAAGGGAGGAGTTTTCTTTTC
  TTACGTTTTGACTTTTGCACACCATATGCACTAGGGATTCTGGAAACTTCTAGCATGACT
  GCAAAGTGGCCAAGAGAATAAAGTCCTTGATGATAAATCACAGTATATCCCTTGAGCCTC
  ACCTTATTGCCAGTGCTAGATTTTTTCTTTTTAATCTCTCCGXXXXXXXXXXXXXXXXXX
  XXXXXTTTTTTTTGGCTAGGCCCACCATGACTTGTGACCTAGAACCCCCAGGATTAACAG
  AGGCCTCACATTTACTCTGCAAGCTGACTCCAAAGGAGTCTACAGTCCTTACTTGTCATG
  CCACACTCACACATCCAGTAGTGGTCTCTATCTACCCGCATTCCTAGCTAGCTGGCACTG
  GCCTCAACTCCAAAGACTGCCTTTAGGACCATCAAATGGCCTATGCAAGCAAGCGGGGTG
  GTTATTAGGACAGATTGTATATTTTGTATATTCTGGGACCATCCCTTCAAGACACGTCTA
  TAAAACAAAAATGGCGCTTGGTCCACACACGGTTGCTGCTCCCTCCTACCAGCTGGCTCC
  CCTCCTGTCCTCCTTTGACTGNTTGACTCATTGACTGTTAAAATGCCACCCCATACATAT
  TTGGGATGCAAAACTGAAGTCAAAAGGAAATAATATAAGAAACACAAACACATATATGAC
  AGCAACCTTCAAGATCTGGGTTTTCAGCTTTCTGCAACCTTTGTTTTCACTGAAATGTTG
  AAACTACTCGTCTGAGGGCAAAGGAACCTCCTCACAAATGCTATAGCTGCCAATTGGACA
  CTTGGGGCATTTCGAGGTCTGGCCCTAAGAATTTACTTTCTCCTTTTCCTTTTTTCTATT
  TAGACCAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003709 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTGGCAGCTTCGTGTCAG
  TGAGTTTGCATCCCCCTTCCTGATCCACGAGCTGGAGTGATTAGAGCCCTGGAAGGGAAT
  TGTTACTCCCGTGGAGAAGTCCCCTTTTCCTGGCAGTCGTCTGCACTGTACACGCTGGAT
  GCCTCTCTCCATCCACCCCACTCACTCGCTCCTCTCTCACCTCCTCTCTCCCTCTCCTGC
  ATTGATTTTTTTTTTTTCCTTTTTAGTTGACTGAAACAAAACAAAACAAAAGGGCCACTG
  GATGTCTGCCTTCTTGGGGGGTGAGCCAGACAGACTGACAAACAAACAGCCCCAACTGTG
  TTCGGGGGAGGGTTTCGCCTCCCGTTTTGCCCGGCAGCAGCAGCATGGACGTGTTGGCTA
  GTTATAGTATATTCCAGGAGCTACAACTTGTCCACGACACCGGCTACTTCTCAGCTTTAC
  CATCCCTGGAGGAGACCTGGCAGCAGACATGCCTTGAATTGGAACGCTACCTACAGACGG
  AGCCCCGGAGGATCTCAGAGACCTTTGGTGAGGACTTGGACTGTTTCCTCCACGCTTCCC
  CTCCCCCGTGCATTGAGGAAAGCTTCCGTCGCTTAGACCCCCTGCTGCTCCCCGTGGAAG
  CGGCCATCTGTGAGAAGAGCTCGGCAGTGGACATCTTGCTCTCTCGGGACAAGTTGCTAT
  CTGAGACCTGCCTCAGCCTCCAGCCGGCCAGCTCTTCTCTAGACAGCTACACAGNCGTNA
  ACCAGGCCCAGCTCAACGCAGTGACCTCATTACCGCCCCATCGTCCCCTGAGCTCAGCCG
  CCATTTGGTCAAACCTCACAACTCTCTCTGCCGGGATGGCCCGTGACTTTAAACTGGTGC
  CANNAAGCTGCTTTCACTCCTAAGTGGGAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_003709 unedited
  GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTCTAAATAGAAAAAAGAAAAG
  GAGAAAGTAAATTCTTAGGGCCAGACCTCGAAATGCCCCAAGTGTCCAATTGGCAGCTAT
  AGCATTTGTGAGGAGGTTCCTTTGCCCTCAGACGAGTAGTTTCAACATTTCAGTGAAAAC
  AAAGGTTGCAGAAAGCTGAAAACCCAGATCTTGAAGGTTGCTGTCATATATGTGTTTGTG
  TTTCTTATATTATTTCCTTTTGACTTCAGTTTTGCATCCCAAATATGTATGGGGTGGCAT
  TTTAACAGTCAATGAGTCAAACAGTCAAAGGAGGACAGGAGGGGAGCCAGCTGGTAGGAG
  GGAGCAGCAACCGTGTGTGGACCAAGCGCCATTTTTGTTTTATAGACGTGTCTTGAAGGG
  ATGGTCCCAGAATATACAAAATATACAATCTGTCCTAATAACCACCCCGCTTGCTTGCAT
  AGGCCATTTGATGGTCCTAAAGGCAGTCTTTGGAGTTGAGGCCAGTGCCAGCTAGCTAGG
  AATGCGGGTAGATAGAGACCACTACTGGATGTGTGAGTGTGGCATGACAAGTAAGGACTG
  TAGACTCCTTTGGAGTCAGCTTGCAGAGTAAATGTGAGGCCTCTGTTAATCCTGGGGGTT
  CTANGTCACAAGTCATGGTGGGCCTAGCCAACAAAAAAAGGAAAGAAAGAAACGTGTCTC
  TTCTTTTAAACAGCCCATGAGAGAAACACCTAACCCTTTTTCTTAAATGTCAACCCCTCA
  CTTCCACAATGGCCGTTTTAAATTGGGTATTGCAACCCGNTGGGGAATATGAGCTCACTG
  GCCATGACCAAAACACAGATGATCCTTTGGGAACCCCTAACCTGGGAGCGCTCCTAATTT
  TCCCACTCTTGGAAGATGAAATTTTGCGTTTTGTCCGGCTAACCACAGATAATAAACCCC
  ACTGCCTTGGACACAGACACATGCGGACTGTCTGGGGACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003709
• Insert Size: 3900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003709.1, NP_003700.1
• RefSeq Size: 1640 bp
• RefSeq ORF: 909 bp
• Locus ID: 8609
• UniProt ID: O75840
• Cytogenetics: 2q33.3
• Domains: zf-C2H2
• Protein Families: Transcription Factors
• Gene Summary: The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.