MSL3L1 (MSL3) (NM_078628) Human Untagged Clone

CAT#: SC110206

MSL3 (untagged)-Human male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MSL3L1
• Synonyms: MRSXBA; MRXS36; MRXSBA; MSL3L1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_078628, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCGCGAGCGAGGGCATGAAATTTAAATTCCACTCAGGGGAGAAAGTGCTGTGCTTCGAGCCTGACC
  CCACCAAGGCGCGAGTGCTGTACGATGCCAAGATTGTTGATGTTATTGTTGGGAAAGACGAAAAAGGCAG
  AAAGATCCCAGAATATCTGATCCATTTTAATGGTTGGAACAGAAGCTGGGATAGATGGGCAGCAGAAGAT
  CATGTGCTTCGTGATACCGATGAAAATCGTAGATTACAGCGTAAATTGGCAAGAAAAGCTGTAGCTCGCC
  TGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGTTGCCTGGTGTGGACTCTGTCTTAAAAGGCCTCCC
  CACTGAAGAAAAAGATGAAAATGATGAAAACTCATTAAGCAGTTCCTCTGACTGTAGTGAAAACAAGGAT
  GAAGAAATAAGTGAAGAAAGTGATATTGAAGAAAAGACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAA
  GAAGGGAAATGGAAGAAAGAACAATAACTATAGAAATCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGA
  TTGTTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATCATAACGATTTTG
  GAATCCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAATGAGAGGCCTCGTCACCATCACG
  TTATGCCACATGCCAACATGAACGTGCATTATATCCCAGCAGAAAAGAATGTTGACCTTTGTAAGGAGAT
  GGTGGATGGATTAAGAATAACCTTTGATTACACTCTCCCGTTGGTTTTACTCTATCCATATGAACAAGCT
  CAGTATAAAAAGGTGACTTCGTCTAAATTTTTTCTTCCAATTAAGGAAAGTGCCACAAGCACTAACAGGA
  GCCAGGAGGAACTCTCTCCCAGTCCGCCTTTGTTGAATCCATCCACGCCACAGTCCACAGAGAGTCAGCC
  GACCACCGGTGAACCAGCCACCCCCAAAAGGCGCAAAGCTGAGCCAGAAGCATTGCAGTCTCTGAGGCGG
  TCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCTGAGAGCAGCGCTTCACCTCAGCCCAAGCGCCGGC
  AGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCCTGCACCTGGAAAAGAGTAGGTTCATTCTCGGGTG
  CCCCAGGCCGGGGAGAGCCAGCGTGTACTTTGTGTTTAGTCAGTGCCAGGCATGGTGCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_078628 unedited
  NGGGTGTTCAAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACGAGGA
  GCAAATGAGCGCGAGCGAGGGCATGAAATTTAAATTCCACTTCAGGGGAGAAAGTGCTGT
  GCTTCGAGCCTGACCCCACCAAGGCGCGAGTGCTGTACGATGCCAAGATTGTTGATGTTA
  TTGTTGGGAAAGACGAAAAAGGCAGAAAGATCCCAGAATATCTGATCCATTTTAATGGTT
  GGAACAGAAGCTGGGATAGATGGGCAGCAGAAGATCATGTGCTTCGTGATACCGATGAAA
  ATCGTAGATTACAGCGTAAATTGGCAAGAAAAGCTGTAGCTCGCCTGAGGAGCACAGGAA
  GAAAGAAGAAGCGCTGCAGGTTGCCTGGTGTGGACTCTGTCTTAAAAGGCCTCCCCACTG
  AAGAAAAAGATGAAAATGATGAAAACTCATTAAGCAGTTCCTCTGACTGTAGTGAAAACA
  AGGATGAAGAAATAAGTGAAGAAAGTGATATTGAAGAAAAGACTGAAGTGAAAGAAGAAC
  CAGAGCTTCAAACAAGAAGGGAAATGGAAGAAAGAACAATAACTATAGAAATCCCTGAAG
  TTCTGAAGAAGCAGCTGGAGGATGATTGTTACTACATTAACAGGAGGAAACGGTTAGTGA
  AACTTCCATGCCAGACCAACATCATAACGATTTTGGAATCCTATGTGAAGCATTTTGCTA
  TCAATGCAGCCTTTTCAGCCAATGAGAGGCCTCGTCACCATCACGTTATGCCACATGCCA
  CATATGAACGTGCATTATATCCCAGCAGAAAAGAATGTTGACCTTTGTAANGAGATGGTG
  GATGGATTAAGAATAACCTTGATTACACTCTCCGTTGGTTTACTCTTCCATATGAACAGC
  TCAGTTTAAAAGTGACTTCGTCTAAATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_078628 unedited
  TATGGACCCGCGGCCGCAATCTAGNGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTCAGGGTCCATAAATCAAGTTTTATTGGAATATAGCACACTCATTTTATTTACATACT
  ATCTGTGGCTACTTTTGGAGTTAAGTAGCCTTGACAGACACCATATGGCCCACAAAGCCG
  AAAGTATTTACCCTCTGGCCCTCTGTGGAAATTGACATCTGTTCTATAAAGTAAAAATAC
  TGGTATTTCAATAATTGCACTTATTTAAAAGATGATTGTCAGTGTAGGGCTGGAATCCTA
  ACAATTTTCTCACTTTAGAAACCAAAACCCACAGTGTTAAGCATAAAATTACGTACAATT
  TTGATAATGTTTACAGTAATAGCAGCAACATGATGCTTTAAGAACCTTGACTTCCACCTA
  TAGAATTGAAGTAATCACAAATGAAGGAACCATTGGGAACAAACATCAAACATTCTTTAC
  CTCGTTTATTTCATTAGTTCTTCTCCCTTCAAAGCCAGCAAACACAGCACTCCCTTCCTT
  GCTAGGAGTCAGAGGAATAGGTGAAGATGATCTGCTATGCACAGGTGTCTCTTCCAAGAA
  AAAGATGAAATTATTCACCAGCAACTGAATTAAAGACTGCCTCAAGACTGTTAAAAACTG
  CGGAACATAAATCTAAACTTGGTTCTCAGAAATTACCAACCTTTAACGATNAGACTTTCC
  TAACAGATAGCACCTGAATTTTATTTTGTTAAAAAAATAAGGAATAAAGCCTGACCTTGC
  TACATGTGGATGAACCTTAAAGACTATGCTAGTGGAGGGGGCCATCCAAAGGGCCCATAC
  TATGTTTCCTTATTTTGAAAACCCGGGTGGGCAATCCCAAAGACCCAAGCGCTTATGGTT
  GCCAGAGCTTCCAAAGGAAGTGGGAGGATTCTACTGGTTTGGGTTTTCCGGGGGGGGGCT
  GAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_078628
• Insert Size: 4700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_078628.1, NP_523352.1
• RefSeq Size: 3564 bp
• RefSeq ORF: 1251 bp
• Locus ID: 10943
• UniProt ID: Q8N5Y2
• Cytogenetics: Xp22.2
• Domains: CHROMO
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (4) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (d) has a distinct C-terminus and is 105 aa shorter than isoform a.