MSL3L1 (MSL3) (NM_006800) Human Untagged Clone

CAT#: SC110205

MSL3 (untagged)-Human male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MSL3L1
• Synonyms: MRSXBA; MRXS36; MRXSBA; MSL3L1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110205 sequence for NM_006800 edited (data generated by NextGen Sequencing)
  ATGGAAGAAAGAACAATAACTATAGAAATCCCTGAAGTTCTGAAGAAGCAGCTGGAGGAT
  GATTGTTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATC
  ATAACGATTTTGGAATCCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAAT
  GAGAGGCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCCCA
  GCAGAAAAGAATGTTGACCTTTGTAAGGAGATGGTGGATGGATTAAGAATAACCTTTGAT
  TACACTCTCCCGTTGGTTTTACTCTATCCATATGAACAAGCTCAGTATAAAAAGGTGACT
  TCGTCTAAATTTTTTCTTCCAATTAAGGAAAGTGCCACAAGCACTAACAGGAGCCAGGAG
  GAACTCTCTCCCAGTCCGCCTTTGTTGAATCCATCCACGCCACAGTCCACAGAGAGTCAG
  CCGACCACCGGTGAACCAGCCACCCCCAAAAGGCGCAAAGCTGAGCCAGAAGCATTGCAG
  TCTCTGAGGCGGTCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCTGAGAGCAGCGCT
  TCACCTCAGCCCAAGCGCCGGCAGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCCTG
  CACCTGGAAAAGAAGACACCTGTGCATAGCAGATCATCTTCACCTATTCCTCTGACTCCT
  AGCAAGGAAGGGAGTGCTGTGTTTGCTGGCTTTGAAGGGAGAAGAACTAATGAAATAAAC
  GAGGTCCTCTCCTGGAAGCTTGTGCCTGACAATTACCCCCCAGGTGACCAGCCGCCTCCA
  CCCTCTTACATTTATGGGGCACAACATTTGCTGCGATTGTTTGTGAAACTTCCAGAAATC
  CTTGGAAAGATGTCCTTTTCTGAGAAGAATCTGAAGGCTTTATTGAAGCACTTTGATCTC
  TTTTTGAGGTTTTTAGCAGAATACCACGATGACTTCTTCCCAGAGTCGGCTTATGTCGCT
  GCCTGTGAGGCACATTACAGCACCAAGAACCCCCGGGCAATTTATTAA
  
  Clone variation with respect to NM_006800.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006800 unedited
  TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGCGCGAGCGAGGGCATGAAA
  TTTAAATTCCACTCAGGGGAGAAAGTGCTGTGCTTCGAGCCTGACCCCACCAAGGCGCGA
  GTGCTGTACGATGCCAAGATTGTTGATGTTATTGTTGGGAAAGACGAAAAAGGCAGAAAG
  ATCCCAGAATATCTGATCCATTTTAATGGTTGGAACAGAAGCTGGGATAGATGGGCAGCA
  GAAGATCATGTGCTTCGTGATACCGATGAAAATCGTAGATTACAGCGTAAATTGGCAAGA
  AAAGCTGTAGCTCGCCTGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGTTGCCTGGT
  GTGGACTCTGTCTTAAAAGGCCTCCCCACTGAAGAAAAAGATGAAAATGATGAAAACTCA
  TTAAGCAGTTCCTCTGACTGTAGTGAAAACAAGGATGAAGAAATAAGTGAAGAAAGTGAT
  ATTGAAGAAAAGACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAAGAAGGGAAATGGAA
  GAAAGAACAATAACTATAGAAATCCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGATTG
  TTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATCATAAA
  CGATTTGGAATNCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAATGAGAG
  GCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCCCAGCAGA
  AAAGAATGTTGACCTTTGTANGGAGNATGNNGGATGGATAANAAATAACCTTTGATTACA
  CTCTCCCGGTGGNTTTTACTCTATCCATAATGACAAGCTCAGTTTAAAAAGGTGACCTCG
  CCTAAATTTTTTCTCCAATTAAGAAAAGTGCCCCAGCCCTATCCGGAGCCCGAAGTACTT
  TTTCCCATCCGGCCTTGTTGATTCCTCCCCGCCCCAGTCCAAGGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006800 unedited
  ATGGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTTCAAACAAG
  AACAGGCTTTATTTAGATCACCAAAAATAACATTTTACAGAAAGGGAACCATAACATTAC
  ACAACAAAGTATAGCTGTAAAATCTCAAATAAGAAAGGCAATGCTTTCTTTAGATCACCA
  AAAATAATGTTTCACAGAGAGGGAACCGTTAGAAGCAAATGCATAGCTGCAAATTTTCTT
  TTGCCATCAATATCGATTCCCTCTAAAATACTTTGAGACTACTTTGTGGTTTCCGAGTAC
  AAACTAAACCTTTTTGGACAGAGTTGCTCGGCTTCATCAAAAAAATAAAACCAATTTGCA
  AAAAAAATTTGTTTAATGCTAACAAATAAAGAGACAATGTGGTTCTTGCTAACTAACTGC
  AATGTCTACTGAAATGGCCTAACCTATTCCACGAATATTTCACTGTGAACATAGTTGCTT
  TTTCCTTGCCATCACAGATGGCCTGCAAAGTAACAAGTGTCGTGTCAGAGCACTTTCAGG
  CACCCAGGGAATCATTCCTAACAGAATAACTGCAGTATGTGGGCAACTCAAACAACAGAG
  CCCCAAGGTGGGCATTGTGTTTGCGCTGTGGGTAAAGACCCACCACCTTGTTAGTTATTC
  ACCCTGGACCCAGAGCGCCAAACTAGACAGAGCAGTTGCTCTTACAGAACCAACAACATT
  NTAATAAATTGCCCGGGGGGTCTTGGTGCTGNTATGTGCCTCACAGGCAGCGACATAAGC
  CGACTCTGGGAAAGAGTCATCGTGGTATTCTGCTAAAAACTCAAAAGAGATCAAGTGCTT
  CATAAAGCCTTCAGATNCTCTAGAAAAGACATCTTTCAGGATTTCTGGAAGTTCACAACA
  TCGCACAATGTTGTGCCCATAATGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006800
• Insert Size: 2340 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006800.2, NP_006791.2
• RefSeq Size: 2305 bp
• RefSeq ORF: 1068 bp
• Locus ID: 10943
• UniProt ID: Q8N5Y2
• Cytogenetics: Xp22.2
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The resulting isoform (c) is 166 aa shorter shorter at the N-terminus, compared to isoform a.