KCNE3 (BC032235) Human Untagged Clone

CAT#: SC104772

(untagged)-Homo sapiens, potassium voltage-gated channel, Isk-related family, member 3, clone MGC:39982 IMAGE:5216128, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNE3
• Synonyms: HOKPP; HYPP; MiRP2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for BC032235, the custom clone sequence may differ by one or more nucleotides
  
  
  CCAGCTCCGAAGTCAATACTGAGATCCCAGATGTGTCCAGAGACATCCTGAAGAGGCTCGGGGGTGGAGG
  AGCCTTAGTGTGTCCACAAAGGGACTCCTGAAACTGACTGAGAGCCAGTGGATTTGCCAGCAGTCTGAGC
  TTCTACCGAGTCTTCCCCCACCTCAATCCCTGTTGCTATGGAGACTACCAATGGAACGGAGACCTGGTAT
  GAGAGCCTGCATGCCGTGCTGAAGGCTCTAAATGCCACTCTTCACAGCAATTTGCTCTGCCGGCCAGGGC
  CAGGGCTGGGGCCAGACAACCAGACTGAAGAGAGGCGGGCCAGCCTACCTGGCCGTGATGACAACTCCTA
  CATGTACATTCTCTTTGTCATGTTTCTATTTGCTGTAACTGTGGGCAGCCTCATCCTGGGATACACCCGC
  TCCCGCAAAGTGGACAAGCGTAGTGACCCCTATCATGTGTATATCAAGAACCGTGTGTCTATGATCTAAC
  ACGAGAGGGCTGGGACGGTGGAAGACCAAGACACCTGGGGATTGCGTCTGGGGCCTCCAGAACTCTGCTG
  TGGACTGCATCAGGTCTCAGTGTCCCTATCTGTAAGATCAACAAGAAACACGGTTAAGGGAGGTCGTCAC
  TGGGGTGGGAGAAGAGGGGCTGGTAGACCGAAGCCTTGTGCATAAGGATTTTTTCCCAGGAAAAGATAGA
  CTTTATAAACAGTGGGAGCCCATGAACAAACATATAAAAGTAGCAACAGATAATGACCAATAACTGGTTC
  AGTGGCTGGAGTATTAGGGGCCTGGGGATTGGAGAACGGAGAAGAAGTTGTAGCAGAGGGAAATGAGACA
  GGAAGATGCTCTGGGGACACATTTTTTATGTGTTATCTTCAGCCATGAGAAGCAGTGATGACTATCCCAT
  ATCACAGATATGATTTACCACCACCACCCTGCCCCCGCTCCCGTGAAGAAAGCAGGGCAAGTGCTGTGCT
  GCCCATTTGGGCCTGCATAGTGCCATGATTGGAACCCAGGAACTCTGGTCTCCTTGCCTAGTGCTTTTCA
  AAACTCTGTGCTACACAGGAGTGGATCCAGGCCTGAAGGTCATACAATTCTGGGGACTCTCTTTAAGAAA
  AAGAATTCTAAAATATCTTACTTTTGCAAACATTATGAAAATATACTGCCACATTAATATGTTGCTAGGG
  CCCCTGCTAGGACCTTAAGAAGGAGCTCATGTGAGTCAGGACCCTGAATGTTAGGCCTCGTTAGCTCTAT
  GGTTCATATGCTTCTTGAACCAAGTCACAGGGCACTTCCCAGCCACATTGCCAGGCAACAGGACTAAACT
  ACCTCCAAAGCAAGCAGTCTTTTCAGTTTTGACTGAGTGATGTGAGAAACTTCTTTTCTTTTCTTTTCTT
  TTTTTTTTTTGAGACAGTCTCCCTATGTCACCCAGGCTGTGGTGCAGCAACCCAATCTTGGCTCGCTGCA
  ACCCCCACCTCCCGGGTTCAAGCAATTATCCTGCCTCAGCCACCTGAGTGGCTGGGATTACAGGTTCCTG
  TCACCACACCCAGTTAATTTATATATATATATATATATATATATATATATATATATATTTAAGTAGAGAC
  AGGGTTTCACATGTTGCCCAGGCTGGTCTCGAACTCCTGTCCTCAAGTTATCTGCCCATTTTGGTCTCCC
  AAAGTGCTGGGATTACAAGTGTAAGCCACCACGACTATCTGAGAGAAGTTTTCTGATGTCATGTTGAATC
  TGCTTCTAAAAGACTGATACTGCCAAGGTGGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGC
  CAACATGGTGAAACCCCATCTACTAAAAAAATACAAAAATTAGCCAGACCTGGTGGCGGGTGCCCGTATT
  CCCAGCTACTTGGGAGGCTGAGGCGGGAGAATTGTTTGGGCCCGGGAGGTGGAGGTTGCAGTGAGCCAGG
  ATCACGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGGCTCTGTCTCAAAAAAAAAACAAAAACAAAAA
  CAAAAAAGACTGATATCGCACCTAAATTATTATTATATTAAAAGAAGCAGAGTATGAGAGACAGGTACAT
  GGTCCAGTAGGAAGAGAAGCAGCCCTGATTCTACCACTTAAGGTGATGTATGATCTTAGGCTGGACACTT
  CTCTCCCTCATCCGTTTTCCTCTTCAACATAATGAAATAGACTTGAAAGTCTCTAAGGCTCTATCAGTTC
  TGACATTCTAGGCTTCATATACATTAAGTTGAGCCATATGTAATCACTGTGTTTGTAGGTTAGAAACAGC
  TGAGTATCGTAGTTTCATATATGGTTCCAGCTAATACATGCAATGTGGCTGGTGAACACTTCTGAATTCA
  GAAACTATCCCAGATCTCAGCTAGAACCATCCACTGTTCTGTTTGTCCAGTTTCAACTTAAGGGATCTCC
  ATGCGGTCCCTGGAAGTACCCATTGAAACATGCGTATTTGTGTATAGCAGAACTCTGAAATAATATTCTG
  ACAGCAGTTATCTCTGAGGAATTGGGTTATAGGTGATTTTCCCTTTCCGCATGATAAATTTATGTAATAT
  TTGACTGACTTGACCGTAAGTATGTTACTTGTATAATAAAAGAAAAAAAGGTAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC032235 unedited
  CAACATTTTGNTAATACGACTCACTATAGGGCGGCCGCGAATTCGCACCAGCTGGGCTTT
  CCCAGCTCCGAAGTCAATACTGAGATCCCAGATGTGTCCAGAGACATCCTGAAGAGGCTC
  GGGGGTGGAGGAGCCTTAGTGTGTCCACAAAGGGACTCCTGAAACTGACTGAGAGCCAGT
  GGATTTGCCAGCAGTCTGAGCTTCTACCGAGTCTTCCCCCACCTCAATCCCTGTTGCTAT
  GGAGACTACCAATGGAACGGAGACCTGGTATGAGAGCCTGCATGCCGTGCTGAAGGCTCT
  AAATGCCACTCTTCACAGCAATTTGCTCTGCCGGCCAGGGCCAGGGCTGGGGCCAGACAA
  CCAGACTGAAGAGAGGCGGGCCAGCCTACCTGGCCGTGATGACAACTCCTACATGTACAT
  TCTCTTTGTCATGTTTCTATTTGCTGTAACTGTGGGCAGCCTCATCCTGGGATACACCCG
  CTCCCGCAAAGTGGACAAGCGTAGTGACCCCTATCATGTGTATATCAAGAACCGTGTGTC
  TATGATCTAACACGAGAGGGCTGGGACGGTGGAAGACCAAGACACCTGGGGATTGCGTCT
  GGGGCCTCCAGAACTCTGCTGTGGACTGCATCAGGTCTCAGTGTCCCTATCTGTAAGATC
  AACAAGAAACACGGTTAAGGGAGGTCGTCACTGGGGTGGGAGAAGAGGGGCTGGTAGACC
  GAAGCCTTGTGCATAAGGATTTTTTTCCCAGGAAAAGATAGACTTTATAAACAGTGGGAG
  CCCATGAACAAACATATAAAAGTAGCAACAGATAATGACCAAATACTGGTTCAGTGGCTG
  GAGTATTAGGGGCCTGGGGATTGGAGAAACGAAAGNAAGTGTAGCANAGGAAATGANACA
  GGAAGAGCTCTGGGGCACATTTTTTATGTGTATCTCAGCCTGAGAAGCATGATGACTATC
  CATAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for BC032235 unedited
  NGCCCCTCTAGNACGCGGCCGCCTTCTAAGATCGGTTTTTTTTTTTTTTTTTTATTTTTT
  CAAAATAGAATACCTTTTTTCCTTTTATTATACAAGTAACATACTTACGGTCAAGTCAGT
  CAAATATTACATAAATTTATCATGCGGAAAGGGAAAATCACCTATAACCCAATTCCTCAG
  AGATAACTGCTATCAGAATATTATTTCAGAGTTCTGCTATACACAAATACGCAGGTTTCA
  ATGGGTACTTCCAGGGACCGCATGGAGATCCCTTAAGTTGAAACTGGACAAACAGAACAG
  TGGATGGTTCTAGCTGAGATCTGGGATAGTTTCTGAATTCAGAAGTGTTCACCAGCCACA
  TTGCATGTATTAGCTGGAACCATATATGAAACTACGATACTCAGCTGTTTCTAACCTACA
  AACACAGTGATTACATATGGCTCAACTTAATGTATATGAAGCCTAGAATGTCAGAACTGA
  TAGAGCCTTAGAGACTTTCAAGTCTATTTCATTATGTTGAAGAGGAAAACGGATGAGGGA
  GAGAAGTGTCCAGCCTAAGATCATACATCACCTTAAGTGGTAGAATCAGGGCTGCTTCTC
  TTCCTACTGGACCATGTACCTGTCTCTCATACTCTGCTTCTTTTAATATAATAATAATTT
  AAGTGCGATATCAGTCTTTTTTGTTTTTGGTTTTGTTTTTCTTTGAGACAGAGCCTTGCT
  CTGTCACCAGCCTGGGAGTGCANTGGCGTGATCCCGGCCCACTGCAACCTCCGCCTCCNA
  GGCCCAAACAATCCTCCCGCCTCAGCCTCCCAGCAGCTGGGAATACGGGCACCCGCCACC
  AGGTCTGGCTATTTTTGTATTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: BC032235
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC032235.1
• RefSeq Size: 2684 bp
• RefSeq ORF: 2684 bp
• Locus ID: 10008
• Cytogenetics: 11q13.4
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]