Abcd1 (NM_001108821) Rat Tagged Lenti ORF Clone
CAT#: RR201592L3
- LentiORF®
Lenti ORF clone of Abcd1 (Myc-DDK-tagged ORF) - Rat ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), (10 ug)
"NM_001108821" in other vectors (3)
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Abcd1 |
Synonyms | RGD1562128 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR201592).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_001108821 |
ORF Size | 2211 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001108821.1, NP_001102291.1 |
RefSeq Size | 3411 bp |
RefSeq ORF | 2214 bp |
Locus ID | 363516 |
UniProt ID | D3ZHR2 |
Cytogenetics | Xq37 |
Gene Summary | Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis (PubMed:12176987). Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation (PubMed:25043761). Involved in several processes; namely, controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance. Controls also the cellular response to oxidative stress by regulating mitochondrial function like, mitochondrial oxidative phosphorylation and depolarization. And finally controls the inflammatory response by positively regulating peroxisomal beta-oxidation of VLCFAs (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN201592 | Abcd1 (untagged ORF) - Rat ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), (10 ug) |
USD 743.00 |
|
RR201592 | Abcd1 (Myc-DDK-tagged ORF) - Rat ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), (10 ug) |
USD 742.00 |
|
RR201592L4 | Lenti ORF clone of Abcd1 (mGFP-tagged ORF) - Rat ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), (10 ug) |
USD 1,042.00 |
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