Camsap2 (NM_001134503) Rat Untagged Clone

CAT#: RN203680

Camsap2 (untagged ORF) - Rat similar to KIAA1078 protein (RGD1310950), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Camsap2
• Synonyms: Camsap1l1; RGD1310950
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN203680 representing NM_001134503
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGGATGCTGCAGACCCGCGGGAGGTGAGAAGGACGTTCATTGTTCCAGCCATCAAACCCTTTGACC
  ACTATGACTTCTCCAGAGCCAAAATCGCCTGCAATCTGGCCTGGCTGGTGGCCAAAGCCTTTGGGACAGA
  AACTGTGCCAGAGGAACTTCGAGAACCATTTTACACAGATCAGTATGACCAGGAACACATCAAGCCCCCT
  GTCGTTAACCTGCTTCTGTCAGCGGAGCTGTACTGTCGTGCTGGCAGTCTCATCCTCAAGAGTGACGCTG
  CAAAGCCCCTCCTGGGCCACGATGCTGTAATCCAGGCATTAGCACACAAAGGCCTGTATGTCACTGACCA
  GGAAAAACTGGTAACTGAAAGAGACCTCCACAAGAAACCCATACAGATGAGTGCACACTTGGCCATGATC
  GATACTCTAATGATGGCTTACACTGTAGAGATGGTCAGCATAGAGAAAGTAATTGCATGTGCTCAACAGT
  ATTCAGCTTTTTTTCAAGCCACAGATCTGCCCTATGATATCGAGGATGCTGTCATGTACTGGATAAATAA
  GGTAAATGAACACTTGAAAGACATAATGGAACAAGAACAAAAATCTAAAGAGCACCACACGGCTGAAGCT
  CCAGGAGGTCAAAAGTCTCCTTCCAAATGGTTTTGGAAACTGGTTCCAGCTCGTTACAGGAAGGAGCAAA
  CACTGCTTAAGCAACTGCCTTGCATTCCATTGGTGGAAAACTTGTTGAAGGACGGCACGGATGGCTGTGC
  GCTGGCTGCCCTCATTCACTTCTACTGCCCTGCTGTTGTCCGACTAGAAGATATTTGTTTGAAAGAAACT
  ATGTCTTTGGCCGACAGTCTGTATAACCTGCAGCTGATTCAGGAATTTTGCCAAGAATACTTAAACCATT
  GCTGCCATTTCAGCTTGGAAGATATGCTTTATGCTGCTTCGTCCATAAAGAGTAATTATTTGGTGTTCAT
  GGCAGAACTCTTCTGGTGGTTCGAAGTTGTGAAGCCTTCCTTTGTGCAGCCTCGTGTTGTCCGTCCACAA
  GGAGCTGAGCCTGCGAAAGACATGCCATCGGTTCCTGTCTTAAATGCTGCCAAAAGAAACGTCCTGGATA
  GTTCTTCTAGTTCTGACTTCACCTCCAGATATACACGTCCCCAAACTCATTCTTCAGTCTCAGGAGGAAT
  TAGAAGGTCTTCATCTATGTCTTATGTTGATGGCTTCATAGGAACATGGCCTAAAGAGAAAAGAACATCT
  GTACATGGCGTTTCATTTGATATTTCTTTCGATAAAGAAGACAATGCCCAGAGCTCCACTCCAAACCGAG
  GAATCATCCGCTCTGTTAGTAATGAGGGGCTCAACAACAGTCGGGCATCCAAACACATTAGGAAAAATCT
  GTCCTTCAAGCCAGTGAATGGAGGAGAAGAGGAAAGCATTGAAGAAGAACTTCATGTCGACCCTCATGGG
  GACCTCAAATCTTACATGCCTCTCAGCACAAATGAACTGAACTCTAATGAGAATACTCACCACAAGCTCC
  CAAACGGGGCTTTACAAAATAGAGTGCTTCTAGATGAGTTTGGGAATCAGATTGAAACTCCGAGCATTGA
  AGAAGCATTACAGATAATCCATGATACTGAAAAACCTCCTCATACAGCGCGGCCAGATCAGATTGCTAAT
  GGCTTCTTTCTTCACGGTCAGGATCTGAGTCTCCTGAATTCAAATATCAAGCTAAGCCAGTCCAGTCCTG
  ATAACATAACTGACCCAAAAGGCGCCTTGAGTCCCATAACTGACACTACAGAAGTCGACACTGGAATTCA
  CGTTCCTTCAGAAGACATTCCCGAAACCATGGACGAGGACTCTTCCTTGAGAGATTATACTGTTAGCTTA
  GACTCTGACATGGATGATGCGTCTAAATTTCTTCAGGACTATGATATAAGAGCCAGCAACCCCAGAGAGG
  CCCTGAGTCCCTGCCCAAGTACCATCAGCACCAAGTCTCAGCCGGGGAGCAGCGCCTCCTCCAGCTCTGG
  GGTGAAAATGACCAGCTTCGCTGAGCAGAAGTTCAGGAAGCTGAATCATACTGATGGGAAGAGTAGTGGG
  AGCAGTTCTCAGAAAACTACCCCGGAAGGCTCAGAGCTGAATATTCCTCACATGGTTTCTTGGGCTCAAA
  TTCCAGAAGAATCGGGTGTTGCCCAAGGCCGGGACACTACACAGCTGTTGGCGTCTGAAATGGTGCATCT
  TAGGATGAGGCTAGAGGAAAAGAGACGTGCTATAGAAGCCCAGAAAAAGAAAATGGAAGCTGCTTTTACC
  AAACAGAGGCAGAAAATGGGAAGGACAGCGTTCCTAACTGTTGTGAAAAAGAAAGGGGATGGGATTTCTC
  CTCTCCGAGAGGAAGCAGCAGGTGCAGAAGACGAGAAAGTATATACTGACCGAGCCAAAGAGAAGGAGTC
  ACAGAAAATGGACGGGCAGAGGAGCAAGTCCTTAGCAGACATAAAAGAAAGCATGGAGAACCCTCAGGGC
  AAATGGCTAAAGTCCCCAAGCACGCCTGTTGATCCCGAGAAGCAGTGGAACCTGACAAGTCCCTCAGAGG
  AGACTTTAAATGAGGGAGAACTTTTAGAGTACACAAAGTCCATCGAAAAGCTGAATTCATCCCTGCACTT
  TCTACAACAGGAAATGCAGCGCTTGTCCCTTCAGCAGGAGATGTTAATGCAGATGAGAGAGCAGCAGTCT
  TGGGTGATCTCACCTCCGCAGCCCTCTCCACAGAAGCAGATCCGCGATTTTAAACCTAGACAGGCAGGCC
  TGTCGTCAGCTGCTGCACCGTTCTCAGCAGACTCCCCACGCCCCACTCATCCGTCTCCGCAGTCTTCTAC
  CAGGAAGAGTGCATCTTTTTCTGTTAAAAATCAAAGGACTCCAAGGCCAAATGAATTAAAAATAACTCCT
  CTGAATCGAACCTTGACACCTCCTCGGTCTGTGGATAGTCTTCCTCGGCTAAGGAGGTTTTCCCCGAGCC
  AGGTTCCCATTCAGACACGGTCGTTCGTATGTTTTGGTGATGATGGAGAGCCCCAAAAAGAGCCCAAACC
  AAAAGAGGAGATTAAAAAGGAGCCTTCAGAGTGCAAAGGGACTTTGGAATCTTGTGACCATAATCCTGGG
  GAGAAGGAGGTTAAACCTCTTGAATCAACAGTGTCTGAAGTGTTGTCACAGCCCATCACAGAGACTGTGT
  GTGTGACACCAAATGAGGACCAACTGAATCAACCCACAGATCCTCCGCCTAAGCCCGTTTTCCCACCTAC
  TGCTCCTAAAAATGTCAATCTGATTGAAGTTTCTCTGTCAGATTTAAAACCCCCTGAAAAGGCTGATGTG
  TCTGTTGAAAAGTTTGATGGAGAGAGTGACAAGGAACAGTTTGATGATGACCAGAAAGTATGCTGTGGCT
  TCTTTTTTAAGGATGATCAAAAGGCAGAAAATGACATGGCCGTGAAACGAGCAGCTCTGTTGGAGAAGCG
  ATTGAGGAGAGAGAAGGAAACTCAGCTTCGGAAGCAGCAGCTGGAAGCGGAGATGGAGCATAGGAAAGAG
  GAGACGAGGCGAAAAACTGAGGAAGAACGTCAGAAGAAAGAGGACGAGCGGGCACGGAGAGAATTCATTA
  GGCAGGAGTACATGAGGCGAAAGCAGCTGAAGCTAATGGAGGACATGGACACAGTAATCAAGCCTCGGCC
  TCAGGTGGCAAAACAGAAAAAACAGCGGCCAAAATCTATTCACAGAGATCATATTGAATCTCCCAAAACA
  CCAATCAAAGGCCCTCCAGTCTCTAGCCTCTCTCTGGCATCGCTGAACACAGGTGATACCGAGAGTGTTC
  ATTCAGGCAAGAGGACACCAAGGTCAGAGTCTGTAGAAGGCTTCTTATCTCCAAGTCGCTGTGGCAGTCG
  GAATGGCGAGAAAGACTGGGAAAACGCATCCACGACCTCTTCAGTGGCTTCTGGAACAGAATACACAGGA
  CCAAAGCTTTACAAGGAACCTAGCGCAAAATCCAATAAACACATAATACAGAATGCATTAGCTCATTGCT
  GTTTGGCTGGAAAAGTAAATGAAGGTCAGAAGAAAAAAATATTAGAGGAAATGGAGAAGTCAGATGCCAA
  CAACTTCTTAATCTTGTTCCGGGATTCAGGCTGCCAGTTCAGGTCTTTGTATACTTACTGCCCAGAAACT
  GAAGAAATCAATAAACTGACTGGGATAGGCCCTAAGTCTATCACTAAAAAGATGATTGAGGGGCTTTACA
  AGTACAATTCTGACAGAAAACAGTTTAGCCACATACCTGCTAAAACCTTATCTGCTAGTGTGGATGCCAT
  TACCATTCATAGCCACTTGTGGCAGACCAAAAGACCAGTGACACCCAAAAAACTCTTACCTACTAAAGCA
  TAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001134503
• Insert Size: 4413 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001134503.1, NP_001127975.1
• RefSeq Size: 7719 bp
• RefSeq ORF: 4413 bp
• Locus ID: 289400
• UniProt ID: D4AEC2
• Cytogenetics: 13q13
• Gene Summary: Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:24908486). Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization (By similarity). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (By similarity). In addition, it also reduces the velocity of microtubule polymerization (By similarity). Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes (By similarity). Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (By similarity). Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation (PubMed:24908486). Through the microtubule cytoskeleton, regulates the autophagosome transport (By similarity).[UniProtKB/Swiss-Prot Function]