CORIN (NM_001278585) Human Tagged ORF Clone
CAT#: RG239804
- TrueORF®
CORIN (tGFP-tagged) - Human corin, serine peptidase (CORIN), transcript variant 2
ORF Plasmid: DDK
"NM_001278585" in other vectors (2)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | CORIN |
Synonyms | ATC2; CRN; Lrp4; PEE5; TMPRSS10 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG239804 representing NM_001278585.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAAACAGTCTCCTGCCCTCGCTCCGGAAGAGCGCTGCCGCAGAGCCGGGTCCCCAAAGCCGGTCTTG AGAGCTGATGACAATAACATGGGCAATGGCTGCTCTCAGAAGCTGGCGACTGCTAACCTCCTCCGGTTC CTATTGCTGGTCCTGATTCCATGTATCTGTGCTCTCGTTCTCTTGCTGGTGATCCTGCTTTCCTATGTT GGTGCCTGTATGAACATCACCCACAGCCAGTGTCAGATGCTGCCCTACCACGCCACGCTGACACCTCTC CTCTCAGTTGTCAGAAACATGGAAATGGAAAAGTTCCTCAAGTTTTTCACATATCTCCATCGCCTCAGT TGCTATCAACATATCATGCTGTTTGGCTGTACCCTCGCCTTCCCTGAGTGCATCATTGATGGCGATGAC AGTCATGGACTCCTGCCCTGTAGGTCCTTCTGTGAGGCTGCAAAAGAAGGCTGTGAATCAGTCCTGGGG ATGGTGAATTACTCCTGGCCGGATTTCCTCAGATGCTCCCAGTTTAGAAACCAAACTGAAAGCAGCAAT GTCAGCAGAATTTGCTTCTCACCTCAGCAGGAAAACGGAAAGCAATTGCTCTGTGGAAGGGGTGAGAAC TTTCTGTGTGCCAGTGGAATCTGCATCCCCGGGAAACTGCAATGTAATGGCTACAACGACTGTGACGAC TGGAGTGACGAGGCTCATTGCAACTGCAGCGAGAATCTGTTTCACTGTCACACAGGCAAGTGCCTTAAT TACAGCCTTGTGTGTGATGGATATGATGACTGTGGGGATTTGAGTGATGAGCAAAACTGTGCCTGTCAC AGCCAGGGTCTGGTGGAATGCAGAAATGGACAATGTATCCCCAGCACGTTTCAATGTGATGGTGACGAG GACTGCAAGGATGGGAGTGATGAGGAGAACTGCAGCGTCATTCAGACTTCATGTCAAGAAGGAGACCAA AGATGCCTCTACAATCCCTGCCTTGATTCATGTGGTGGTAGCTCTCTCTGTGACCCGAACAACAGTCTG AATAACTGTAGTCAATGTGAACCAATTACATTGGAACTCTGCATGAATTTGCCCTACAACAGTACAAGT TATCCAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATCAGCTGGGAGTCTTCTCTTTTCCCT GCACTTGTTCAAACCAACTGTTATAAATACCTCATGTTCTTTTCTTGCACCATTTTGGTACCAAAATGT GATGTGAATACAGGCGAGCATATCCCTCCTTGCAGGGCATTGTGTGAACACTCTAAAGAACGCTGTGAG TCTGTTCTTGGGATTGTGGGCCTACAGTGGCCTGAAGACACAGATTGCAGTCAATTTCCAGAGGAAAAT TCAGACAATCAAACCTGCCTGATGCCTGATGAATATGTGGAAGAATGCTCACCTAGTCATTTCAAGTGC CGCTCAGGACAGTGTGTTCTGGCTTCCAGAAGATGTGATGGCCAGGCCGACTGTGACGATGACAGTGAT GAGGAAAACTGTGGTTGTAAAGAGAGAGATCTTTGGGAATGTCCATCCAATAAACAATGTTTGAAGCAC ACAGTGATCTGCGATGGGTTCCCAGACTGCCCTGATTACATGGACGAGAAAAACTGCTCATTTTGCCAA GATGATGAGCTGGAATGTGCAAACCATGCGTGTGTGTCACGTGACCTGTGGTGTGATGGTGAAGCCGAC TGCTCAGACAGTTCAGATGAATGGGACTGTGTGACCCTCTCTATAAATGTGAACTCCTCTTCCTTTCTG ATGGTTCACAGAGCTGCCACAGAACACCATGTGTGTGCAGATGGCTGGCAGGAGATATTGAGTCAGCTG GCCTGCAAGCAGATGGGTTTAGGAGAACCATCTGTGACCAAATTGATACAGGAACAGGAGAAAGAGCCG CGGTGGCTGACATTACACTCCAACTGGGAGAGCCTCAATGGGACCACTTTACATGAACTTCTAGTAAAT GGGCAGTCTTGTGAGAGCAGAAGTAAAATTTCTCTTCTGTGTACTAAACAAGACTGTGGGCGCCGCCCT GCTGCCCGAATGAACAAAAGGATCCTTGGAGGTCGGACGAGTCGCCCTGGAAGGTGGCCATGGCAGTGT TCTCTGCAGAGTGAACCCAGTGGACATATCTGTGGCTGTGTCCTCATTGCCAAGAAGTGGGTTCTGACA GTTGCCCACTGCTTCGAGGGGAGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTA GACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACCATCATCCTGCATCCCCGCTACAGTCGA GCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTACGTCCGG CCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGC CACATGGGCAATAAAATGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGT CAGTCCTACTTTGACATGAAGACCATCACCACTCGGATGATATGTGCTGGCTATGAGTCTGGCACAGTT GATTCATGCATGGGTGACAGCGGTGGGCCTCTTGTTTGTGAGAAGCCTGGAGGACGGTGGACATTATTT GGATTAACTTCATGGGGCTCCGTCTGCTTTTCCAAAGTCCTGGGGCCTGGCGTTTATAGTAATGTGTCA TATTTCGTCGAATGGATTAAAAGACAGATTTACATCCAGACCTTTCTCCTAAAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239804
Blue=ORF Red=Cloning site Green=Tag(s) MKQSPALAPEERCRRAGSPKPVLRADDNNMGNGCSQKLATANLLRFLLLVLIPCICALVLLLVILLSYV GACMNITHSQCQMLPYHATLTPLLSVVRNMEMEKFLKFFTYLHRLSCYQHIMLFGCTLAFPECIIDGDD SHGLLPCRSFCEAAKEGCESVLGMVNYSWPDFLRCSQFRNQTESSNVSRICFSPQQENGKQLLCGRGEN FLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCACH SQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNSL NNCSQCEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKC DVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKC RSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCSFCQ DDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQL ACKQMGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRP AARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNL DHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYITGWG HMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLF GLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001278585 |
ORF Size | 2814 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001278585.1, NP_001265514.1 |
RefSeq Size | 4703 bp |
RefSeq ORF | 2817 bp |
Locus ID | 10699 |
UniProt ID | Q9Y5Q5 |
Cytogenetics | 4p12 |
Protein Families | Druggable Genome, Protease, Transmembrane |
MW | 105.6 kDa |
Gene Summary | This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] |
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