PNLDC1 (NM_001271862) Human Tagged ORF Clone
CAT#: RG238745
- TrueORF®
PNLDC1 (tGFP-tagged) - Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1), transcript variant 1
ORF Plasmid: DDK
"NM_001271862" in other vectors (2)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | PNLDC1 |
Synonyms | HsPNLDC1 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG238745 representing NM_001271862.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGACGTGGGCGCCGACGAGTTCGAGGAGAGCCTCCCTCTGCTGCAGGAGCTCGTCCAGGAGGCCGAC TTCGTGGGTCTGGACATAGAGTTCACGGGCCTTCGTTCTAACCTGTCTGGGCCCCAGCAGATCAGTCTT TTTGATTTGCCATCGGAGTGGTATCTAAAGACCCGTCAGAGTGTTCAGCAATTTACAGTCTGTCAGATT GGATTGTCTGTGTTTTCCGCTATTGAAGGAGAGGCAAACAAGTATATAGCCCATTCTTGTAACTTCTAT CTCTTCCCTACAACGTTTGGGATTTTGGACTCAGAATTCTCCTTCCAGGCTTCCAGTGTTCAGTTTTTG AATCAGTATGGCTTCAACTATAACAAGTTTCTCAAAAACGGAATCCCATATATGAATGAAGAACAGGAG AAGAAAATTAGACACGATATCCTGACTGGGAACTGGAGAGTTCGCAGCTCTCCGGATAAAGACCAAATC AAGGTGGTGATTGACGAAGTGACGCGGTGGCTGGAGCTGGCCAAGGAAGGCGACTGGATGACTCTTCCT GGGATCACTGGCTTCCAGGCCTTTGAGGTCCAACTGGTGCTGAGGCAGGCCCTCCCCAACATCTGGACG GTGCTGAAAGATGAGGGGGTGGTAGTGAAGAAAGTGAGTAAACAACATCGTTGGTATCTTCAGAACACC TCTTGTGACCGAGAGAGCTGTTGGAAGGAAAATATTCTTCTCTCAGCAAGGGGTTTTTCTGTCTTTTTC CAAATGCTGGTGAAAGCCCAGAAGCCCTTAGTGGGACATAATATGATGATGGACCTGCTGCACCTCCAT GAGAAGTTCTTCAGACCCCTCCCAGAAAGCTACGATCAATTTAAGCAGAATATCCACAGCCTATTTCCT GTTCTCATTGATACCAAGAGTGTAACAAAGGATATCTGGAAGGAGATGAATTTCCCGAGGGTGTCGAAT CTTTCGGAAGTCTATGAAGTCCTGAACAGTGACTTGAATCCCACCAAGAATTCTGGACCAGAGATTGTT CACGCGAGCAGGTGTGAGAAATATGTTGAGACAAAGTGCCCCCACGAAGCCGCGTATGATGCCTTCCTC TGTGGGTCAGTTCTTTTGAAAGTGGCACACTTGCTTCTACAGAAGATATACCACATCGACCCCGTGCCC GAGTCATCCTTTCCTCAGTACCTTGACGTGCTGGCTCCTTACGTGAACCAAGTGAACCTCATCCGAGCG GGGGTCCCAAAGATCAATTTTTCTGGTCCAGATTATCCCAGTATCCGACCTCCCATCCTCATCCTCAGC GTCAAAAGGTGGCCTGGGGTCAGCGAGCAGCAAGTCTACCATAAGTTTCAGAATCTCTGCAAGTTTGAT GTCAGGCGACTCACAAGAAGCCAGTTCTTACTCCTGACCAATAAGTTTAAGGATGCGCGGAACATCCTG AAGGAGTACCGGGACCACCCGACCCTGTGCATCTCCCTGTACCGCTACTGGAGGCACTCCCCAAACGTC AACTGCCTGCTCCAAGTCTGTGGCATAGTGACTGCCTGGGCCCTTCTCGCGTTCATCCTTGGAAGATCT GGTACC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG238745
Blue=ORF Red=Cloning site Green=Tag(s) MDVGADEFEESLPLLQELVQEADFVGLDIEFTGLRSNLSGPQQISLFDLPSEWYLKTRQSVQQFTVCQI GLSVFSAIEGEANKYIAHSCNFYLFPTTFGILDSEFSFQASSVQFLNQYGFNYNKFLKNGIPYMNEEQE KKIRHDILTGNWRVRSSPDKDQIKVVIDEVTRWLELAKEGDWMTLPGITGFQAFEVQLVLRQALPNIWT VLKDEGVVVKKVSKQHRWYLQNTSCDRESCWKENILLSARGFSVFFQMLVKAQKPLVGHNMMMDLLHLH EKFFRPLPESYDQFKQNIHSLFPVLIDTKSVTKDIWKEMNFPRVSNLSEVYEVLNSDLNPTKNSGPEIV HASRCEKYVETKCPHEAAYDAFLCGSVLLKVAHLLLQKIYHIDPVPESSFPQYLDVLAPYVNQVNLIRA GVPKINFSGPDYPSIRPPILILSVKRWPGVSEQQVYHKFQNLCKFDVRRLTRSQFLLLTNKFKDARNIL KEYRDHPTLCISLYRYWRHSPNVNCLLQVCGIVTAWALLAFILGRSGT TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001271862 |
ORF Size | 1593 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001271862.2 |
RefSeq Size | 1859 bp |
RefSeq ORF | 1596 bp |
Locus ID | 154197 |
UniProt ID | Q8NA58 |
Cytogenetics | 6q25.3 |
MW | 61.8 kDa |
Gene Summary | 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC238745 | PNLDC1 (myc-DDK-tagged) - Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1), transcript variant 1 |
USD 544.00 |
|
SC336639 | PNLDC1 (untagged) - Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1), transcript variant 1 |
USD 545.00 |
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