GPR6 (NM_001286099) Human Tagged ORF Clone

CAT#: RG237844

GPR6 (tGFP-tagged) - Human G protein-coupled receptor 6 (GPR6), transcript variant 1

Product Images

Circular map for RG237844

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: GPR6
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG237844 representing NM_001286099.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGACACTCCTAGCTTGGTGCACTCGGGGTGCAAATCCGGCCGCGATGAACGCGAGCGCCGCCTCGCTC
  AACGACTCCCAGGTGGTGGTAGTGGCGGCCGAAGGAGCGGCGGCGGCGGCCACAGCAGCAGGGGGGCCG
  GACACGGGCGAATGGGGACCCCCTGCTGCGGCGGCTCTAGGAGCCGGCGGCGGAGCTAATGGGTCTCTG
  GAGCTGTCCTCGCAGCTGTCGGCTGGGCCACCGGGACTCCTGCTGCCAGCGGTGAATCCGTGGGACGTG
  CTCCTGTGCGTGTCGGGGACAGTGATCGCTGGAGAAAACGCGCTGGTGGTGGCGCTCATCGCGTCCACT
  CCGGCGCTGCGCACGCCCATGTTCGTGCTGGTAGGCAGCCTGGCCACCGCTGACCTGTTGGCGGGCTGT
  GGCCTCATCTTGCACTTTGTGTTCCAGTACTTGGTGCCCTCGGAGACTGTGAGTCTGCTCACGGTGGGC
  TTCCTCGTGGCCTCCTTCGCCGCCTCTGTCAGCAGCCTGCTGGCCATTACGGTGGACCGCTACCTGTCC
  CTGTATAACGCGCTCACCTATTACTCGCGCCGGACCCTGTTGGGCGTGCACCTCCTGCTTGCCGCCACT
  TGGACCGTGTCCCTAGGCCTGGGGCTGCTGCCCGTGCTGGGCTGGAACTGCCTGGCAGAGCGCGCCGCC
  TGCAGCGTGGTGCGCCCGCTGGCGCGCAGCCACGTGGCTCTGCTCTCCGCCGCCTTCTTCATGGTCTTC
  GGCATCATGCTGCACCTGTACGTGCGCATCTGCCAGGTGGTCTGGCGCCACGCGCACCAGATCGCGCTG
  CAGCAGCACTGCCTGGCGCCACCCCATCTCGCTGCCACCAGAAAGGGTGTGGGTACACTGGCTGTGGTG
  CTGGGCACTTTCGGCGCCAGCTGGCTGCCCTTCGCCATCTATTGCGTGGTGGGCAGCCATGAGGACCCG
  GCGGTCTACACTTACGCCACCCTGCTGCCCGCCACCTACAACTCCATGATCAATCCCATCATCTATGCC
  TTCCGCAACCAGGAGATCCAGCGCGCCCTGTGGCTCCTGCTCTGTGGCTGTTTCCAGTCCAAAGTGCCC
  TTTCGTTCCAGGTCTCCCAGCGAGGTC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG237844
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MTLLAWCTRGANPAAMNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSL
  ELSSQLSAGPPGLLLPAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGC
  GLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAAT
  WTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIAL
  QQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATYNSMINPIIYA
  FRNQEIQRALWLLLCGCFQSKVPFRSRSPSEV
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001286099
• ORF Size: 1131 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).

Reference Data

• RefSeq: NM_001286099.1, NP_001273028.1
• RefSeq Size: 1966 bp
• RefSeq ORF: 1134 bp
• Locus ID: 2830
• UniProt ID: P46095
• Cytogenetics: 6q21
• Protein Families: Druggable Genome, GPCR, Transmembrane
• MW: 39.9 kDa
• Gene Summary: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).[UniProtKB/Swiss-Prot Function]