DCXR (NM_001195218) Human Tagged ORF Clone
CAT#: RG231089
- TrueORF®
DCXR (tGFP-tagged) - Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2
ORF Plasmid: DDK
Lentiviral Particles: DDK w/ Puro mGFP w/ Puro
AAV Particle: DDK
"NM_001195218" in other vectors (3)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | DCXR |
Synonyms | DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG231089 representing NM_001195218
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCTGTTCCTCGCGGGCCGCCGGGTGCTGGTCACCGGGGCAGGCAAAGGGCGCGGCACGGTCCAGG CGCTGCACGCGACGGGCGCGCGGGTGGTGGCTGTGAGCCGGACTCAGGCGGATCTTGACAGCCTTGTCCG CGAGTGCCCGGGGATAGAACCCGTGTGCGTGGACCTGGGTGACTGGGAGGCCACCGAGCGGGCGCTGGGC AGCGTGGGCCCCGTGGACCTGCTGGTGAACAACGCCGCTGTCGCCCTGCTGCAGCCCTTCCTGGAGGTCA CCAAGGAGGCCTTTGACAGATCCTTTGAGGTGAACCTGCGTGCGGTCATCCAGGTGTCGCAGATTGTGGC CAGGGGCTTAATAGCCCGGGGAGTCCCAGGGGCCATCGTGAATGTCTCCAGCCAGTGCTCCCAGCGGGCA GTAACTAACCATAGCGTCTACTGCTCCACCAAGGGTGCCCTGGACATGCTGACCAAGGTGATGGCCCTAG AGCTCGGGCCCCACAAGATCCGAGTGAATGCAGTAAACCCCACAGTGGTGATGACGTCCATGGGCCAGGC CACCTGGAGTGACCCCCACAAGGCCAAGACTATGCTGAACCGAATCCCACTTGGCAAGTTTGCTGAGGTA GAGCACGTGGTGAACGCCATCCTCTTTCTGCTGAGTGACCGAAGTGGCATGACCACGGGTTCCACTTTGC CGGTGGAAGGGGGCTTCTGGGCCTGC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG231089 representing NM_001195218
Red=Cloning site Green=Tags(s) MELFLAGRRVLVTGAGKGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALG SVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRA VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEV EHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001195218 |
ORF Size | 726 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001195218.1, NP_001182147.1 |
RefSeq Size | 854 bp |
RefSeq ORF | 729 bp |
Locus ID | 51181 |
UniProt ID | Q7Z4W1 |
Cytogenetics | 17q25.3 |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Pentose and glucuronate interconversions |
Gene Summary | The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC231089 | DCXR (Myc-DDK-tagged)-Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2 |
USD 300.00 |
|
RC231089L3 | Lenti ORF clone of Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2, Myc-DDK-tagged |
USD 600.00 |
|
RC231089L4 | Lenti ORF clone of Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2, mGFP tagged |
USD 600.00 |
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