DVL1 (NM_004421) Human Tagged ORF Clone
CAT#: RG217691
- TrueORF®
DVL1 (tGFP-tagged) - Human dishevelled, dsh homolog 1 (Drosophila) (DVL1)
ORF Plasmid: DDK
Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro
"NM_004421" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | DVL1 |
Synonyms | DRS2; DVL; DVL1L1; DVL1P1 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG217691 representing NM_004421
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGAGACCAAGATTATCTACCACATGGACGAGGAGGAGACGCCGTACCTGGTCAAGCTGCCCGTGG CCCCCGAGCGCGTCACGCTGGCCGACTTCAAGAACGTGCTCAGCAACCGGCCCGTGCACGCCTACAAATT CTTCTTTAAGTCCATGGACCAGGACTTCGGGGTGGTGAAGGAGGAGATCTTTGATGACAATGCCAAGCTT CCCTGCTTCAACGGCCGCGTGGTCTCCTGGCTGGTCCTGGCTGAGGGTGCTCACTCGGATGCGGGGTCCC AGGGCACGGACAGCCACACAGACCTGCCCCCGCCTCTTGAGCGGACAGGCGGCATCGGGGACTCCCGGCC CCCCTCCTTCCACCCGAATGTGGCCAGCAGCCGTGACGGGATGGACAACGAGACAGGCACGGAGTCCATG GTCAGTCACCGGCGGGAGCGTGCCCGACGCCGGAACCGCGAGGAGGCCGCCCGGACCAATGGGCACCCAA GGGGAGACCGACGGCGGGATGTGGGGCTGCCCCCAGACAGCGCGTCCACCGCCCTCAGCAGCGAGCTTGA GTCCAGCAGCTTTGTGGACTCGGACGAGGATGGCAGCACGAGCAGGCTCAGCAGCTCCACGGAGCAGAGC ACCTCATCCAGACTCATCCGGAAGCACAAACGCCGGCGGAGGAAGCAGCGCCTTCGGCAGGCGGACCGGG CCTCCTCCTTCAGCAGCATAACCGACTCCACCATGTCCCTCAACATCGTCACTGTCACGCTCAACATGGA AAGACATCACTTTCTGGGCATCAGCATCGTGGGGCAGAGCAACGACCGTGGAGACGGCGGCATCTACATT GGCTCCATCATGAAGGGCGGGGCTGTGGCCGCTGACGGCCGCATCGAGCCCGGCGACATGTTGCTGCAGG TGAATGACGTGAACTTTGAGAACATGAGCAATGACGATGCCGTGCGGGTGCTGCGGGAGATCGTTTCCCA GACGGGGCCCATCAGCCTCACTGTGGCCAAGTGCTGGGACCCAACGCCCCGAAGCTACTTCACCGTCCCA CGGGCTGACCCGGTGCGGCCCATCGACCCCGCCGCCTGGCTGTCCCACACGGCGGCACTGACAGGAGCCC TGCCCCGCTACGAGCTGGAAGAGGCGCCGCTGACGGTGAAGAGTGACATGAGCGCCGTCGTCCGGGTCAT GCAGCTGCCAGACTCGGGACTGGAGATCCGCGACCGCATGTGGCTCAAGATCACCATCGCCAATGCCGTC ATCGGGGCGGACGTGGTGGACTGGCTGTACACACACGTGGAGGGCTTCAAGGAGCGGCGGGAGGCCCGGA AGTACGCCAGCAGCTTGCTGAAGCACGGCTTCCTGCGGCACACGGTCAACAAGATCACCTTCTCCGAGCA GTGCTACTACGTCTTCGGGGATCTCTGCAGCAATCTCGCCACCCTGAACCTCAACAGTGGCTCCAGTGGG ACTTCGGATCAGGACACGCTGGCCCCGCTGCCCCACCCGGCTGCCCCCTGGCCTCTGGGTCAGGGCTACC CCTACCAGTACCCGGGACCCCCACCCTGCTTCCCGCCTGCCTACCAGGACCCGGGCTTTAGCTATGGCAG CGGCAGCACCGGGAGTCAGCAGAGTGAAGGGAGCAAAAGCAGTGGGTCCACCCGGAGCAGCCGCCGGGCC CCGGGCCGTGAGAAGGAGCGTCGGGCGGCGGGAGCTGGGGGCAGTGGCAGTGAATCGGATCACACGGCAC CGAGTGGGGTGGGGAGCAGCTGGCGAGAGCGTCCGGCCGGCCAGCTCAGCCGTGGCAGCAGCCCACGCAG TCAGGCCTCGGCTACCGCCCCGGGGCTCCCCCCGCCCCACCCCACGACCAAGGCCTATACAGTGGTGGGG GGGCCACCCGGGGGACCCCCTGTCCGGGAGCTGGCTGCCGTCCCCCCGGAATTGACAGGCAGCCGCCAGT CCTTCCAGAAGGCTATGGGGAACCCCTGCGAGTTCTTCGTGGACATCATG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG217691 representing NM_004421
Red=Cloning site Green=Tags(s) MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKL PCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESM VSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQS TSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYI GSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVP RADPVRPIDPAAWLSHTAALTGALPRYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAV IGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSG TSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRA PGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVG GPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_004421 |
ORF Size | 2010 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_004421.2, NP_004412.2 |
RefSeq Size | 2941 bp |
RefSeq ORF | 2013 bp |
Locus ID | 1855 |
UniProt ID | O14640 |
Cytogenetics | 1p36.33 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway |
Gene Summary | DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC217691 | DVL1 (Myc-DDK-tagged)-Human dishevelled, dsh homolog 1 (Drosophila) (DVL1) |
USD 614.00 |
|
RC217691L1 | Lenti ORF clone of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), Myc-DDK-tagged |
USD 914.00 |
|
RC217691L2 | Lenti ORF clone of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), mGFP tagged |
USD 914.00 |
|
RC217691L3 | Lenti ORF clone of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), Myc-DDK-tagged |
USD 914.00 |
|
RC217691L4 | Lenti ORF clone of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), mGFP tagged |
USD 914.00 |
|
SC303481 | DVL1 (untagged)-Human dishevelled, dsh homolog 1 (Drosophila) (DVL1) |
USD 614.00 |
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