Histone acetyltransferase MYST3 (KAT6A) (NM_001099413) Human Tagged ORF Clone
CAT#: RG212980
- TrueORF®
KAT6A (tGFP-tagged) - Human MYST histone acetyltransferase (monocytic leukemia) 3 (MYST3), transcript variant 2
ORF Plasmid: DDK
"NM_001099413" in other vectors (2)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | Histone acetyltransferase MYST3 |
Synonyms | MOZ; MRD32; MYST3; RUNXBP2; ZC2HC6A; ZNF220 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG212980 representing NM_001099413
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTTTGGAGGCCATCAAAAAAGTGAAAAAGCAGA AACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATCGTAAAACTGT TTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCC TATAAAGATCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATA AACAAAATGTGGATTGGAATAAACTGATAAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAAC TTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCATTATTCGGAGGCAGTGCTGCC TCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATG GACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTG TTTACCTCCAGTGTCCCTTCTTCCACATGAAAAGGATAAGCCGGTTGCTGAACCAATCCCCATCTGTAGT TTCTGTCTTGGTACAAAAGAACAAAACCGAGAAAAGAAGCCAGAGGAACTCATCTCCTGTGCCGACTGTG GCAACAGTGGCCATCCATCCTGTTTAAAGTTTTCCCCTGAACTAACGGTTCGAGTGAAGGCCTTACGGTG GCAGTGCATCGAGTGTAAAACATGCAGCTCCTGTCGAGATCAAGGCAAAAATGCGGATAACATGCTCTTT TGTGATTCATGTGACCGAGGTTTTCACATGGAGTGTTGTGATCCGCCACTCACCCGTATGCCAAAAGGCA TGTGGATATGTCAAATATGTCGACCTAGGAAAAAAGGACGAAAACTTCTACAAAAGAAGGCAGCACAGAT AAAACGGCGCTATACTAATCCAATAGGACGTCCAAAAAACAGGTTAAAGAAACAAAACACGGTATCAAAA GGTCCCTTCAGCAAAGTTCGAACTGGCCCTGGAAGGGGTAGGAAACGAAAAATCACTCTTTCCAGCCAAT CAGCATCATCATCATCAGAAGAAGGATATTTAGAGCGGATAGATGGCTTGGACTTCTGCAGAGATAGCAA TGTCTCCTTGAAGTTCAACAAGAAAACCAAAGGGCTCATTGATGGCCTTACCAAATTTTTTACCCCTTCC CCTGATGGGCGGAAAGCTCGGGGGGAAGTGGTGGACTACTCTGAGCAATATCGAATCAGAAAGAGGGGCA ACAGGAAATCAAGCACTTCAGATTGGCCCACAGACAATCAGGATGGCTGGGATGGCAAACAAGAAAATGA GGAGCGACTTTTTGGGAGCCAGGAAATCATGACTGAGAAAGATATGGAATTATTTCGTGATATCCAAGAA CAAGCACTGCAGAAAGTTGGAGTGACTGGTCCCCCTGATCCACAAGTCCGCTGTCCCTCTGTCATTGAGT TTGGGAAGTATGAAATTCACACCTGGTACTCCTCCCCATATCCTCAAGAATACTCAAGGCTGCCCAAATT GTATCTTTGTGAATTTTGTCTAAAATATATGAAAAGTAGAACTATTCTGCAGCAGCACATGAAGAAATGT GGTTGGTTCCATCCTCCTGCCAATGAGATTTACAGAAAGAATAATATTTCTGTCTTTGAGGTTGATGGGA ATGTGAGTACCATTTATTGTCAAAACCTGTGTCTTTTGGCAAAGTTGTTTCTTGACCACAAAACCCTCTA TTACGATGTGGAGCCATTTCTTTTTTATGTACTAACACAGAATGATGTCAAGGGCTGCCACCTTGTTGGC TACTTTTCTAAGGAAAAGCACTGCCAACAGAAGTACAATGTTTCCTGTATAATGATTCTTCCTCAATACC AGCGTAAGGGCTATGGCAGGTTTCTCATCGATTTCAGTTATTTGTTATCAAAGCGTGAAGGCCAAGCAGG GTCTCCAGAGAAACCGTTATCTGATCTGGGTCGTCTTTCCTACATGGCATATTGGAAAAGTGTAATATTG GAGTGCCTTTATCACCAAAATGACAAGCAGATCAGCATTAAGAAGTTAAGCAAGTTGACTGGAATCTGCC CTCAAGACATCACTTCCACACTCCACCACCTACGAATGCTGGACTTCCGTAGTGACCAATTTGTGATTAT CCGCCGGGAAAAACTTATCCAGGATCACATGGCAAAGCTTCAGCTGAATTTGCGACCTGTAGATGTAGAT CCAGAATGTTTGCGCTGGACTCCAGTCATAGTGTCCAACTCTGTGGTCTCAGAGGAGGAAGAAGAGGAGG CTGAGGAAGGAGAAAACGAAGAGCCACAGTGCCAGGAAAGAGAATTAGAGATCAGTGTGGGAAAGTCTGT GTCTCATGAGAACAAAGAACAAGATTCTTATTCAGTAGAAAGTGAAAAGAAACCAGAAGTTATGGCTCCA GTCAGTTCTACACGTTTGAGCAAACAAGTCCTTCCTCATGATAGTCTTCCTGCAAATAGCCAGCCATCTC GGAGGGGCCGCTGGGGGAGGAAGAACAGAAAAACCCAGGAACGTTTTGGTGATAAAGATTCTAAACTGCT CTTGGAAGAGACGTCTTCAGCTCCTCAGGAACAATATGGAGAATGTGGGGAGAAATCAGAAGCCACCCAG GAACAATACACTGAAAGTGAAGAACAGCTGGTGGCTTCTGAGGAGCAGCCAAGCCAGGACGGGAAACCTG ACCTTCCCAAGAGAAGACTCAGTGAGGGGGTTGAGCCCTGGCGAGGACAGCTCAAGAAAAGCCCTGAGGC TCTGAAGTGCAGATTAACAGAAGGAAGTGAGAGGCTGCCCCGTCGCTACAGTGAGGGTGACAGGGCTGTC CTCAGGGGCTTCAGTGAGAGCAGCGAGGAGGAGGAGGAGCCGGAAAGCCCTCGGTCAAGCTCGCCACCAA TTCTCACAAAGCCCACGCTGAAGCGAAAGAAACCATTTCTCCACCGAAGGAGGAGAGTCCGAAAGCGCAA ACACCACAATAGCAGTGTAGTCACAGAAACTATTTCTGAGACCACTGAAGTGTTAGATGAACCTTTTGAA GATTCTGACTCCGAGAGGCCAATGCCAAGATTAGAACCCACGTTTGAGATCGATGAAGAAGAGGAGGAAG AGGATGAAAATGAACTTTTCCCTAGAGAATACTTCCGTCGTTTGTCTTCGCAGGATGTACTCAGGTGTCA GTCCTCTTCTAAGAGGAAGTCTAAAGATGAAGAAGAAGATGAAGAGTCAGATGATGCTGATGACACTCCT ATCTTAAAGCCAGTATCTCTTTTGCGAAAACGTGATGTGAAGAATTCTCCTCTTGAGCCAGATACATCCA CACCTTTGAAAAAGAAAAAGGGATGGCCCAAAGGCAAGAGCCGCAAACCAATCCACTGGAAGAAAAGACC TGGTCGAAAACCAGGATTTAAGTTGAGTCGGGAAATCATGCCAGTTTCTACTCAAGCATGCGTCATTGAG CCCATCGTTTCCATTCCTAAAGCTGGACGTAAACCCAAGATCCAGGAGAGTGAAGAAACTGTTGAGCCAA AAGAAGACATGCCCCTACCCGAGGAGAGGAAGGAGGAGGAGGAGATGCAAGCAGAGGCAGAAGAGGCTGA AGAGGGTGAGGAAGAGGATGCAGCCAGCAGTGAAGTCCCAGCAGCCTCTCCAGCAGACAGCAGCAATAGT CCTGAGACCGAAACCAAGGAGCCTGAGGTGGAGGAGGAAGAAGAGAAGCCCCGTGTCTCAGAGGAGCAGA GGCAGTCAGAGGAGGAGCAGCAGGAATTAGAGGAGCCAGAGCCAGAGGAGGAGGAAGATGCAGCTGCAGA GACTGCCCAGAATGACGACCACGACGCTGATGATGAGGATGATGGCCACCTGGAGTCCACAAAGAAAAAG GAGCTAGAGGAACAGCCCACGAGGGAAGATGTCAAGGAGGAGCCTGGTGTTCAAGAGTCTTTTTTAGATG CTAATATGCAGAAGAGTAGGGAAAAGATAAAGGATAAAGAGGAAACCGAGCTGGATTCCGAAGAGGAGCA GCCTTCCCATGACACGTCCGTGGTGTCAGAGCAGATGGCTGGGTCTGAGGACGACCACGAAGAAGACTCC CACACTAAGGAAGAGTTAATCGAATTAAAAGAGGAGGAAGAGATTCCTCATAGTGAGCTGGATCTGGAAA CTGTACAGGCAGTGCAGTCTTTGACTCAAGAAGAAAGCAGTGAGCATGAGGGCGCCTACCAGGACTGTGA GGAAACTCTTGCGGCGTGTCAGACCCTGCAGAGTTACACCCAGGCTGACGAGGACCCTCAGATGTCCATG GTTGAAGACTGTCATGCGTCAGAACATAATAGCCCTATCTCCTCCGTTCAGTCTCACCCCAGCCAGTCAG TCCGTTCGGTCAGCAGTCCCAACGTGCCTGCCCTTGAGAGTGGCTACACCCAGATCAGCCCAGAACAAGG ATCCCTGTCCGCACCCTCTATGCAGAACATGGAGACCAGCCCCATGATGGATGTGCCTTCCGTATCAGAC CACTCTCAGCAGGTGGTGGACAGCGGCTTCAGTGACCTGGGCAGCATTGAGAGCACCACTGAAAACTATG AGAACCCAAGCAGTTACGACTCCACGATGGGCGGCAGCATCTGTGGGAACAGCTCTTCCCAGAGCAGCTG CTCCTACGGTGGGCTGTCGTCCTCCAGCAGCCTCACCCAGAGCAGCTGTGTGGTCACTCAGCAGATGGCC AGCATGGGCAGCAGCTGCAGCATGATGCAGCAGAGCAGCGTCCAGCCTGCTGCCAACTGCAGCATCAAGT CACCTCAGAGCTGCGTGGTGGAGAGGCCTCCCAGTAACCAGCAGCAGCAGCCGCCACCACCGCCTCCACA GCAGCCACAGCCGCCGCCGCCACAACCACAACCAGCACCACAGCCTCCACCACCCCAGCAGCAGCCGCAA CAGCAGCCGCAGCCTCAGCCCCAGCAGCCTCCACCCCCACCCCCTCCCCAGCAGCAGCCCCCGCTGTCAC AGTGTAGTATGAATAACAGTTTCACCCCAGCTCCTATGATCATGGAGATACCAGAATCTGGAAGCACTGG GAACATAAGTATCTATGAGAGGATTCCAGGGGATTTTGGTGCCGGCAGCTACTCTCAACCATCAGCCACC TTCAGCCTAGCCAAGCTGCAGCAGCTGACCAACACCATTATGGACCCTCATGCCATGCCTTATAGCCATT CTCCTGCTGTGACTTCCTATGCAACCAGTGTTTCTCTGTCCAATACAGGACTGGCTCAGCTGGCTCCATC TCATCCCTTAGCTGGGACTCCTCAAGCACAAGCCACCATGACGCCACCCCCAAACTTGGCATCCACTACC ATGAACCTCACATCTCCTCTGCTTCAGTGCAACATGTCTGCCACCAACATTGGCATTCCTCACACGCAGA GATTGCAAGGGCAAATGCCAGTGAAGGGGCACATTTCCATCCGCTCCAAGTCTGCGCCACTGCCCTCTGC GGCTGCTCACCAGCAGCAGCTGTATGGCCGTAGCCCATCGGCAGTTGCCATGCAGGCTGGCCCTCGCGCA CTGGCTGTTCAGCGTGGCATGAACATGGGGGTTAATCTGATGCCTACTCCCGCCTATAATGTCAATTCCA TGAATATGAACACCTTGAATGCCATGAACAGCTATCGAATGACACAGCCCATGATGAACAGCAGTTACCA TAGTAACCCTGCCTACATGAACCAGACAGCACAGTATCCTATGCAGATGCAGATGGGAATGATGGGGAGC CAGGCCTATACCCAGCAGCCTATGCAGCCTAACCCTCATGGGAACATGATGTACACAGGCCCCTCCCATC ACAGCTACATGAACGCTGCTGGCGTGCCCAAGCAGTCACTCAACGGACCTTACATGAGAAGA ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG212980 representing NM_001099413
Red=Cloning site Green=Tags(s) MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNS YKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAA SGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKESCESLSCLPPVSLLPHEKDKPVAEPIPICS FCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLF CDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYTNPIGRPKNRLKKQNTVSK GPFSKVRTGPGRGRKRKITLSSQSASSSSEEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPS PDGRKARGEVVDYSEQYRIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQE QALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKC GWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVG YFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVIL ECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVD PECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQ EQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAV LRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFE DSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTP ILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIE PIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKK ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDS HTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSM VEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSD HSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMA SMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQ QQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSAT FSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTT MNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAAAHQQQLYGRSPSAVAMQAGPRA LAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGS QAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001099413 |
ORF Size | 6012 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001099413.1, NP_001092883.1 |
RefSeq Size | 9241 bp |
RefSeq ORF | 6015 bp |
Locus ID | 7994 |
Cytogenetics | 8p11.21 |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017] |
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