STAT2 (NM_005419) Human Tagged ORF Clone
CAT#: RG208592
- TrueORF®
STAT2 (tGFP-tagged) - Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1
ORF Plasmid: DDK
Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro
"NM_005419" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | STAT2 |
Synonyms | IMD44; ISGF-3; P113; PTORCH3; STAT113 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG208592 representing NM_005419
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCAGTGGGAAATGCTGCAGAATCTTGACAGCCCCTTTCAGGATCAGCTGCACCAGCTTTACTCGC ACAGCCTCCTGCCTGTGGACATTCGACAGTACTTGGCTGTCTGGATTGAAGACCAGAACTGGCAGGAAGC TGCACTTGGGAGTGATGATTCCAAGGCTACCATGCTATTCTTCCACTTCTTGGATCAGCTGAACTATGAG TGTGGCCGTTGCAGCCAGGACCCAGAGTCCTTGTTGCTGCAGCACAATTTGCGGAAATTCTGCCGGGACA TTCAGCCCTTTTCCCAGGATCCTACCCAGTTGGCTGAGATGATCTTTAACCTCCTTCTGGAAGAAAAAAG AATTTTGATCCAGGCTCAGAGGGCCCAATTGGAACAAGGAGAGCCAGTTCTCGAAACACCTGTGGAGAGC CAGCAACATGAGATTGAATCCCGGATCCTGGATTTAAGGGCTATGATGGAGAAGCTGGTAAAATCCATCA GCCAACTGAAAGACCAGCAGGATGTCTTCTGCTTCCGATATAAGATCCAGGCCAAAGGGAAGACACCCTC TCTGGACCCCCATCAGACCAAAGAGCAGAAGATTCTGCAGGAAACTCTCAATGAACTGGACAAAAGGAGA AAGGAGGTGCTGGATGCCTCCAAAGCACTGCTAGGCCGATTAACTACCCTAATCGAGCTACTGCTGCCAA AGTTGGAGGAGTGGAAGGCCCAGCAGCAAAAAGCCTGCATCAGAGCTCCCATTGACCACGGGTTGGAACA GCTGGAGACATGGTTCACAGCTGGAGCAAAGCTGTTGTTTCACCTGAGGCAGCTGCTGAAGGAGCTGAAG GGACTGAGTTGCCTGGTTAGCTATCAGGATGACCCTCTGACCAAAGGGGTGGACCTACGCAACGCCCAGG TCACAGAGTTGCTACAGCGTCTGCTCCACAGAGCCTTTGTGGTAGAAACCCAGCCCTGCATGCCCCAAAC TCCCCATCGACCCCTCATCCTCAAGACTGGCAGCAAGTTCACCGTCCGAACAAGGCTGCTGGTGAGACTC CAGGAAGGCAATGAGTCACTGACTGTGGAAGTCTCCATTGACAGGAATCCTCCTCAATTACAAGGCTTCC GGAAGTTCAACATTCTGACTTCAAACCAGAAAACTTTGACCCCCGAGAAGGGGCAGAGTCAGGGTTTGAT TTGGGACTTTGGTTACCTGACTCTGGTGGAGCAACGTTCAGGTGGTTCAGGAAAGGGCAGCAATAAGGGG CCACTAGGTGTGACAGAGGAACTGCACATCATCAGCTTCACGGTCAAATATACCTACCAGGGTCTGAAGC AGGAGCTGAAAACGGACACCCTCCCTGTGGTGATTATTTCCAACATGAACCAGCTCTCAATTGCCTGGGC TTCAGTTCTCTGGTTCAATTTGCTCAGCCCAAACCTTCAGAACCAGCAGTTCTTCTCCAACCCCCCCAAG GCCCCCTGGAGCTTGCTGGGCCCTGCTCTCAGTTGGCAGTTCTCCTCCTATGTTGGCCGAGGCCTCAACT CAGACCAGCTGAGCATGCTGAGAAACAAGCTGTTCGGGCAGAACTGTAGGACTGAGGATCCATTATTGTC CTGGGCTGACTTCACTAAGCGAGAGAGCCCTCCTGGCAAGTTACCATTCTGGACATGGCTGGACAAAATT CTGGAGTTGGTACATGACCACCTGAAGGATCTCTGGAATGATGGACGCATCATGGGCTTTGTGAGTCGGA GCCAGGAGCGCCGGCTGCTGAAGAAGACCATGTCTGGCACCTTTCTACTGCGCTTCAGTGAATCGTCAGA AGGGGGCATTACCTGCTCCTGGGTGGAGCACCAGGATGATGACAAGGTGCTCATCTACTCTGTGCAACCG TACACGAAGGAGGTGCTGCAGTCACTCCCGCTGACTGAAATCATCCGCCATTACCAGTTGCTCACTGAGG AGAATATACCTGAAAACCCACTGCGCTTCCTCTATCCCCGAATCCCCCGGGATGAAGCTTTTGGGTGCTA CTACCAGGAGAAAGTTAATCTCCAGGAACGGAGGAAATACCTGAAACACAGGCTCATTGTGGTCTCTAAT AGACAGGTGGATGAACTGCAACAACCGCTGGAGCTTAAGCCAGAGCCAGAGCTGGAGTCATTAGAGCTGG AACTAGGGCTGGTGCCAGAGCCAGAGCTCAGCCTGGACTTAGAGCCACTGCTGAAGGCAGGGCTGGATCT GGGGCCAGAGCTAGAGTCTGTGCTGGAGTCCACTCTGGAGCCTGTGATAGAGCCCACACTATGCATGGTA TCACAAACAGTGCCAGAGCCAGACCAAGGACCTGTATCACAGCCAGTGCCAGAGCCAGATTTGCCCTGTG ATCTGAGACATTTGAACACTGAGCCAATGGAAATCTTCAGAAACTGTGTAAAGATTGAAGAAATCATGCC GAATGGTGACCCACTGTTGGCTGGCCAGAACACCGTGGATGAGGTTTACGTCTCCCGCCCCAGCCACTTC TACACTGATGGACCCTTGATGCCTTCTGACTTC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG208592 representing NM_005419
Red=Cloning site Green=Tags(s) MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLFFHFLDQLNYE CGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVES QQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRR KEVLDASKALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELK GLSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRL QEGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPK APWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKI LELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQP YTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSN RQVDELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMV SQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF YTDGPLMPSDF TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_005419 |
ORF Size | 2553 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_005419.4 |
RefSeq Size | 4451 bp |
RefSeq ORF | 2556 bp |
Locus ID | 6773 |
UniProt ID | P52630 |
Cytogenetics | 12q13.3 |
Domains | SH2, STAT |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Chemokine signaling pathway, Jak-STAT signaling pathway |
Gene Summary | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208592 | STAT2 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 |
USD 779.00 |
|
RC208592L1 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, Myc-DDK-tagged |
USD 1,079.00 |
|
RC208592L2 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mGFP tagged |
USD 1,079.00 |
|
RC208592L3 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, Myc-DDK-tagged |
USD 1,079.00 |
|
RC208592L4 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mGFP tagged |
USD 1,079.00 |
|
SC108848 | STAT2 (untagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 |
USD 780.00 |
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