PTPRN2 (NM_130842) Human Tagged Lenti ORF Clone
CAT#: RC213126L4
- LentiORF®
Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2, mGFP tagged
"NM_130842" in other vectors (4)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | PTPRN2 |
Synonyms | IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213126).
|
Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_130842 |
ORF Size | 2994 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_130842.1, NP_570857.1 |
RefSeq Size | 4716 bp |
RefSeq ORF | 2997 bp |
Locus ID | 5799 |
UniProt ID | Q92932 |
Cytogenetics | 7q36.3 |
Domains | Y_phosphatase, PTPc_motif |
Protein Families | Druggable Genome, Phosphatase |
Protein Pathways | Type I diabetes mellitus |
MW | 109.4 kDa |
Gene Summary | This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC213126 | PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2 |
USD 914.00 |
|
RC213126L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2, Myc-DDK-tagged |
USD 1,214.00 |
|
RG213126 | PTPRN2 (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2 |
USD 1,114.00 |
|
SC315054 | PTPRN2 (untagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2 |
USD 1,006.00 |
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