Rtn3 (NM_001271487) Mouse Tagged ORF Clone
CAT#: MR228826
- TrueORF®
Rtn3 (myc-DDK-tagged) - Mouse reticulon 3 (Rtn3), transcript variant 6
"NM_001271487" in other vectors (1)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Rtn3 |
Synonyms | RTN3-A1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR228826 representing NM_001271487
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGAGTCGTCAGCGGCCACTCAGTCCCCGTCAGTCTCCTCGTCGTCCTCCGGGGCCGAGCCGTCAG CTCTCGGCGGCGGCGGCGGGAGCCCTGGAGCCTGCCCCGCCCTGGGGGCGAAGAGCTGCGGCTCCTCGTG TGCGGATTCCTTTGTTTCTTCCTCTTCCTCTCAGCCTGTATCTATATTTTCGACCTCACAAGTGCACGAT CTGATTTTCTGGCGAGATGTGAAGAAGACTGGGTTTGTCTTTGGCACCACACTGATCATGCTGCTCTCTC TGGCAGCCTTCAGTGTTATCAGTGTGGTCTCTTACCTCATCCTGGCTCTTCTCTCTGTCACCATCAGCTT CAGAGTCTATAAGTCTGTCATTCAAGCTGTGCAGAAGTCAGAAGAAGGACATCCATTCAAGGCCTACTTG GATGTGGACATTACCCTGTCTTCAGAAGCTTTCCACAACTACATGAATGCTGCGATGGTGCATGTCAACA AGGCCCTCAAACTCATTATTCGTCTCTTTCTGGTAGAAGACTTGGTTGACTCCTTGAAGCTGGCTGTCTT CATGTGGCTGATGACCTATGTTGGTGCTGTTTTTAATGGAATTACCCTTCTGATTCTCGCCGAGCTGCTT GTCTTCAGCGTCCCAATTGTCTATGAGAAGTATAAGACACAGATTGACCACTATGTTGGGATTGCCCGGG ATCAGACCAAGTCAATTGTTGAAAAGATCCAAGCAAAGCTTCCTGGAATCGCCAAAAAAAAGGCAGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR228826 representing NM_001271487
Red=Cloning site Green=Tags(s) MAESSAATQSPSVSSSSSGAEPSALGGGGGSPGACPALGAKSCGSSCADSFVSSSSSQPVSIFSTSQVHD LIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYL DVDITLSSEAFHNYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELL VFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001271487 |
ORF Size | 768 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001271487.1, NP_001258416.1 |
RefSeq Size | 2914 bp |
RefSeq ORF | 771 bp |
Locus ID | 20168 |
UniProt ID | Q9ES97 |
Cytogenetics | 19 A |
MW | 27.8 kDa |
Gene Summary | May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress (By similarity). Induces the formation of endoplasmic reticulum tubules (PubMed:24262037).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC226615 | Rtn3 (untagged) - Mouse reticulon 3 (Rtn3), transcript variant 6 |
USD 330.00 |
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