Men1 (NM_008583) Mouse Tagged Lenti ORF Clone
CAT#: MR226666L4
- LentiORF®
Lenti ORF clone of Men1 (mGFP-tagged) - Mouse multiple endocrine neoplasia 1 (Men1), transcript variant 2
"NM_008583" in other vectors (4)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Men1 |
Synonyms | AW045611 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226666).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_008583 |
ORF Size | 1833 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_008583.2, NP_032609.1 |
RefSeq Size | 2980 bp |
RefSeq ORF | 1836 bp |
Locus ID | 17283 |
UniProt ID | O88559 |
Cytogenetics | 19 A |
Gene Summary | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression (By similarity). May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC219612 | Men1 (untagged) - Mouse multiple endocrine neoplasia 1 (Men1), transcript variant 2, (10ug) |
USD 627.00 |
|
MG226666 | Men1 (tGFP-tagged) - Mouse multiple endocrine neoplasia 1 (Men1) transcript variant 2, (10ug) |
USD 826.00 |
|
MR226666 | Men1 (Myc-DDK-tagged) - Mouse multiple endocrine neoplasia 1 (Men1), transcript variant 2 |
USD 626.00 |
|
MR226666L3 | Lenti ORF clone of Men1 (Myc-DDK-tagged) - Mouse multiple endocrine neoplasia 1 (Men1), transcript variant 2 |
USD 926.00 |
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