Tradd (NM_001033161) Mouse Tagged Lenti ORF Clone
CAT#: MR223646L4
- LentiORF®
Lenti ORF clone of Tradd (mGFP-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd)
"NM_001033161" in other vectors (4)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Tradd |
Synonyms | 9130005N23Rik; AA930854 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223646).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001033161 |
ORF Size | 930 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001033161.2, NP_001028333.1 |
RefSeq Size | 1385 bp |
RefSeq ORF | 933 bp |
Locus ID | 71609 |
UniProt ID | Q3U0V2 |
Cytogenetics | 8 53.04 cM |
Gene Summary | Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC211207 | Tradd (untagged) - Mouse TNFRSF1A-associated via death domain (Tradd), (10ug) |
USD 330.00 |
|
MG223646 | Tradd (tGFP-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd), (10ug) |
USD 500.00 |
|
MR223646 | Tradd (Myc-DDK-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd) |
USD 300.00 |
|
MR223646L3 | Lenti ORF clone of Tradd (Myc-DDK-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd) |
USD 600.00 |
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