Bmp3 (NM_173404) Mouse Tagged Lenti ORF Clone
CAT#: MR223213L4
- LentiORF®
Lenti ORF clone of Bmp3 (mGFP-tagged) - Mouse bone morphogenetic protein 3 (Bmp3)
"NM_173404" in other vectors (4)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Bmp3 |
Synonyms | 9530029I04Rik; D630004D15R |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223213).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_173404 |
ORF Size | 1407 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_173404.3, NP_775580.1 |
RefSeq Size | 3112 bp |
RefSeq ORF | 1407 bp |
Locus ID | 110075 |
UniProt ID | Q8BHE5 |
Cytogenetics | 5 48.24 cM |
Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. Homozygous knockout mice for this gene exhibit increased bone density and volume, while overexpression of this gene in a transgenic mouse causes bone defects resulting in spontaneous rib fractures. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC216355 | Bmp3 (untagged) - Mouse bone morphogenetic protein 3 (Bmp3), (10ug) |
USD 503.00 |
|
MG223213 | Bmp3 (tGFP-tagged) - Mouse bone morphogenetic protein 3 (Bmp3), (10ug) |
USD 657.00 |
|
MR223213 | Bmp3 (Myc-DDK-tagged) - Mouse bone morphogenetic protein 3 (Bmp3) |
USD 457.00 |
|
MR223213L3 | Lenti ORF clone of Bmp3 (Myc-DDK-tagged) - Mouse bone morphogenetic protein 3 (Bmp3) |
USD 757.00 |
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