Psen2 (NM_011183) Mouse Tagged Lenti ORF Clone
CAT#: MR222924L3
- LentiORF®
Lenti ORF clone of Psen2 (Myc-DDK-tagged) - Mouse presenilin 2 (Psen2), transcript variant 1
"NM_011183" in other vectors (4)
Interest in protein/lysate? Submit request here!
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Psen2 |
Synonyms | Ad4; Ad4h; ALG; ALG-3; Alg3; P; PS; PS-2; PS2; Psnl2; STM2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222924).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_011183 |
ORF Size | 1344 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_011183.2 |
RefSeq Size | 1991 bp |
RefSeq ORF | 1347 bp |
Locus ID | 19165 |
UniProt ID | Q61144 |
Cytogenetics | 1 84.19 cM |
Gene Summary | This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex, which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum, where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex, the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG207152 | Psen2 (tGFP-tagged) - Mouse presenilin 2 (Psen2) |
USD 657.00 |
|
MG222924 | Psen2 (tGFP-tagged) - Mouse presenilin 2 (Psen2) transcript variant 1, (10ug) |
USD 657.00 |
|
MR222924 | Psen2 (Myc-DDK-tagged) - Mouse presenilin 2 (Psen2), transcript variant 1 |
USD 457.00 |
|
MR222924L4 | Lenti ORF clone of Psen2 (mGFP-tagged) - Mouse presenilin 2 (Psen2), transcript variant 1 |
USD 757.00 |
{0} Product Review(s)
Be the first one to submit a review