Hip1 (NM_146001) Mouse Tagged Lenti ORF Clone
CAT#: MR211131L4
- LentiORF®
Lenti ORF clone of Hip1 (mGFP-tagged) - Mouse huntingtin interacting protein 1 (Hip1)
"NM_146001" in other vectors (4)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Hip1 |
Synonyms | 2610109B09Rik; A930014B11Rik; E130315I21Rik; mKIAA4113 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211131).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_146001 |
ORF Size | 3087 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_146001.2, NP_666113.2 |
RefSeq Size | 7883 bp |
RefSeq ORF | 3090 bp |
Locus ID | 215114 |
UniProt ID | Q8VD75 |
Cytogenetics | 5 75.18 cM |
Gene Summary | Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11577110). Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (PubMed:12839988, PubMed:17329427). Regulates presynaptic nerve terminal activity (PubMed:17928447). Enhances androgen receptor (AR)-mediated transcription (By similarity). May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (By similarity). Binds 3-phosphoinositides (via ENTH domain) (By similarity). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (By similarity). May play a functional role in the cell filament networks (By similarity). May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11604514, PubMed:14998932, PubMed:16967501, PubMed:17928447).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC203942 | Hip1 (untagged) - Mouse huntingtin interacting protein 1 (Hip1), (10ug) |
USD 830.00 |
|
MG211131 | Hip1 (tGFP-tagged) - Mouse huntingtin interacting protein 1 (Hip1) |
USD 1,096.00 |
|
MR211131 | Hip1 (Myc-DDK-tagged) - Mouse huntingtin interacting protein 1 (Hip1) |
USD 896.00 |
|
MR211131L3 | Lenti ORF clone of Hip1 (Myc-DDK-tagged) - Mouse huntingtin interacting protein 1 (Hip1) |
USD 1,196.00 |
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