Proc (NM_008934) Mouse Untagged Clone
CAT#: MC227922
Proc (untagged) - Mouse protein C (Proc), transcript variant 1
"NM_008934" in other vectors (1)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Proc |
Synonyms | P; PC |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC227922 representing NM_008934
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCTACCTGGACGAAATTGCAGTTTCTCCTTGGCCCACGCCTGTGTCAGCAGCTCCAGGATGTGGC AATTCAGAGTCTTCCTGCTGCTCATGTCCACCTGGGGAATATCTAGCATACCGGCCCATCCTGACCCAGT GTTCTCCAGCAGCGAGCATGCCCACCAGGTGCTTCGGGTCAGACGTGCCAACAGCTTCCTGGAAGAGATG CGGCCAGGCAGCCTGGAACGGGAGTGTATGGAGGAGATCTGTGACTTCGAGGAGGCCCAGGAGATTTTCC AAAATGTGGAAGACACACTGGCCTTCTGGATCAAGTACTTTGACGGTGACCAGTGCTCGGCTCCACCCTT GGACCACCAGTGCGACAGCCCATGCTGCGGGCATGGCACTTGCATCGACGGCATAGGCAGCTTCAGCTGC AGCTGCGATAAGGGCTGGGAGGGCAAGTTCTGTCAGCAGGAGTTGCGCTTCCAGGACTGTCGGGTGAACA ATGGCGGCTGCTTGCACTACTGCCTGGAGGAGAGCAATGGGCGGCGCTGCGCTTGTGCCCCGGGCTATGA GCTGGCAGACGACCACATGCGCTGCAAGTCCACTGTGAATTTTCCATGTGGGAAACTGGGGAGGTGGATA GAGAAGAAACGCAAGATCCTCAAACGAGACACAGACTTAGAAGATGAACTGGAACCAGATCCAAGGATAG TCAACGGAACGCTGACGAAGCAGGGTGACAGTCCTTGGCAGGCAATCCTTCTGGACTCCAAGAAGAAGCT GGCCTGCGGAGGGGTGCTCATCCACACTTCCTGGGTGCTGACGGCAGCCCACTGCGTGGAGGGCACCAAG AAGCTTACCGTGAGGCTTGGTGAGTATGATCTGCGACGCAGGGACCACTGGGAGCTGGACCTGGACATCA AGGAGATCCTCGTCCACCCTAACTACACCCGGAGCAGCAGTGACAACGACATTGCTCTGCTCCGCCTAGC CCAGCCAGCCACTCTCTCCAAAACCATAGTGCCCATCTGCCTGCCGAACAATGGGCTGGCGCAGGAGCTC ACTCAGGCTGGCCAGGAGACAGTGGTGACAGGCTGGGGCTATCAAAGCGACAGAATCAAGGATGGCAGAA GGAACCGCACCTTCATCCTCACCTTCATCCGCATCCCTTTGGTTGCTCGAAATGAGTGCGTGGAGGTCAT GAAGAATGTGGTCTCGGAGAACATGCTGTGTGCAGGCATCATTGGGGACACGAGAGACGCCTGTGATGGT GACAGTGGGGGGCCCATGGTGGTCTTCTTTCGGGGTACCTGGTTCCTGGTGGGCCTGGTGAGCTGGGGTG AGGGCTGTGGGCACACCAACAACTATGGCATCTACACCAAAGTGGGAAGCTACCTCAAATGGATTCACAG TTACATTGGGGAAAAGGGTGTCTCCCTTAAGAGCCAGAAGCTATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_008934 |
Insert Size | 1446 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_008934.4, NP_032960.3 |
RefSeq Size | 1584 bp |
RefSeq ORF | 1446 bp |
Locus ID | 19123 |
Cytogenetics | 18 B1 |
Gene Summary | This gene encodes the vitamin K-dependent protein C, which plays a vital role in the anticoagulation pathway. The encoded protein undergoes proteolytic processing including activation by thrombin-thrombomodulin complex to form the anticoagulant serine protease that degrades activated coagulation factors. A complete lack of the encoded protein in mice results in severe perinatal consumptive coagulopathy in the brain and liver, resulting in death within 24 hours after birth. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature protein. [provided by RefSeq, Sep 2015] Transcript Variant: This variant (1) encodes the longest isoform (1). This isoform (1) may undergo proteolytic processing similar to isoform 2. |
Documents
Product Manuals |
FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR230133 | Proc (myc-DDK-tagged) - Mouse protein C (Proc), transcript variant 1 |
USD 503.00 |
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