Casp8ap2 (NM_011997) Mouse Untagged Clone
CAT#: MC225082
Casp8ap2 (untagged) - Mouse caspase 8 associated protein 2 (Casp8ap2), transcript variant 1, (10ug)
"NM_011997" in other vectors (2)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Frequently bought together (3)
Other products for "Casp8ap2"
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Casp8ap2 |
Synonyms | D4Ertd659e; FLASH |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC225082 representing NM_011997
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAGCAGATGATGACAATGGTGATGGAACGGGTTTGTTTGATGTCTGTCCTGCCTCTCCACTTAAAA ATAATGATGAAGGCTCATTGGACATATATGCTGGGTTGGACAGTGCTGTTTCTGACAGTACTGCTAGATC CTGTGTGTCATTCAGAAACTGTTTAGATTTGTATGAAGAGATCCTGACTGAAGAAGGAACTGCGAAGGAG GCAACGTACAATGACTTGCAGATAGAATATGGGAAATGTCAGCAGCAAATGAAAGACCTGATGAAAAGGT TTAAGGAAATACAGACACAGAACTTGAACTTAAAAAATGAAAACCAGTCTCTTAAGAAGAATATCTCAGC ACTTATCAAAACTGCCAGAGTGGAGATAAACCGTAAGGATGAAGAGATAAATCATCTTCACCAAAGATTG TCTGAGTTTCCACATTTTCGAAATAACCATAAAACTGCAAGAACAAAAGATTCACAGTCCACATCTCCCC ATTTGGATGATTGTTCAAAGACTGATCACGGAGTTAAAAGTGATGTTCAGAAAGATGTACATCCTAACAC TGCACAGCCAAACTTGGAAAAGGAAGGAAAATCGCATTCTGAAGCACAGAATCCTTTGCACTTGTCTACG GGTGTTGAGAAACATTGTGCCAATAATGTCTGGTCACGTTCTCCTTACCAGGTTGGAGAAGGTAACTCAA ATGAGGATAATAGGAGAGGAAGGAGTGGCACTAGACATAGCCAGTGTAGCAGAGGAACTGATAGAACACA GAAAGACTTACATAGCAGCTGTAATGACAGTGAGCCAAGGGACAAGGAGGCTAACTCCAGACTACAAGGA CACCCTGAGAAACATGGCAACAGTGAAGCAAGGACGGAGAGCAAAATTTCAGAGAGTAAAAGCAGCACTG GTATGGGATATAAAAGTGAGCGCAGTGCCTCTTCTTGGGAAAAAGAGACTTCCAGAGAAAGGCCACACAC TCGAGTGGAATCTCAACATGACAAAAATCTAGAGAAACAAAATGAAAGATTACAAAATATGCACAGAAAA GAGCTTCCGTCTCAGGACAAAACAGAAAGAAAAGTTGATGTGAAGTTTAAACCAGCAGGAGAGGAGCAGG GGCATCGGGGAAGAGTGGACCGGGCGTTACCTCCTCATCCCAAGAATGACGTGAAACATTACGGCTTCAA TAAGTATCATCCAGAAGAGAGAAGGGGAAGGGAAGATTGTAAAAGAGACAGAGGGATGAACAGTCATGGC TTTCAAGATAGAAGATGTTCATCTTTTCTTTCAAGCAACAGAAATAGCAAATACCCGCACTCCAAGGAAG TTAGTGTTGCACACCAGTGGGAAAATACTCCTTTCAAAGCAGAAAGACATAGAACTGAGGACAGGAGGAA AAGAGAACGAGAAAACAAAGAAGAAAGTAGACATGTGAAAAGTGACAAAAAATCACCTCCAGAACACTTA CAAAGGACTCATAAAGACACTAAGAAAAGCACTGCTGATGGAAAGAGACAGACTGAGCCCAAACATGGTA AAGGTGCAGTCTCTAACAGTGAGCTTTCTAAAGGGACAGACAGTAAAGAAGGTGCAACAAAGGTGGAGAG TGGGCCAAATGAAGCAAAAGGCAAGGACTTAAAGTTAAGCTTCATGGAAAAACTGAACTTAACTCTTTCT CCTGCTAAAAAGCAGCCTGCTTGTCAAGATAACCCACATCAAATAACTGGTGTTCCCGAGCCCAGTGGCA CGTGTGACTCACGGTCCTTGGAGACGACTGGAACGGTGGCATGCCTTCCTTCTGGCAGTGAACATAATAG AGAGGAAACCAAATCAGAGTTACCAGAGCCAAAGGAGGCTCTTTTGGCAACATCTCAACTCAGGATCAGC ATTCCAGAAAACAAAATGAAGGAAGAAAAGAGGTTGTTATTTAAATCTGTTGAGAATACTGTGCCTTGTG AACTGCTTGCTTGTGGCACGGAAATTTCCCTCCCAGCACCTGTAGAAATTGAACAAGCAAGATGCTTGCT TGGATCAGTGGAAGTGGAAGAGACCTGTGGTGGTGCAAGGACAGCCGCTTCTGTGGTGATGCATGTGTTA CCAGAACATGCTTCTGAAGATGCCAGCCAAGAATTGGACACCAAAAGACACGATGGTATAAATGCTTGTG CTATTTCTGAAGGTGTGAAAACAAAGGTGATTCTTTCACCAAAAGCAGCTGCAGCCAGTGAGAGCCATCT TGCACCTTTGGTTGAAGAACCTAGCATTTCACTAGTAAACTGTTCGGGAGACAATAATCCTAAACTTGAA CCTTCTCTTGAAGAGAGGCCTATAGTTGAGACTAAATCCTGTCCTTTGGAGTCTTGTTTACCTAAAGAGA CTTTTGTACCTTCACCACAGAAGACTGAGTTGATTGACCACAAAATAGAAACTGGAGAATCAAACTCAGT ATATCAAGATGATGATAACTCAGTTTTGAGTATTGACTTTAATAATCTGAGACCTATTCCAGACCCCATC AGCCCTCTGAATAGTCCAGTGAGACCGGTATGCAAAGTTGTTAGCATGGAGAGCTCATGTGCAATTCCAC TGTATGATAGCAGTCATAAAGATGAGTTTCCATCCAATTCAACTCTTTCTACCTTCAAGAGTCAGTCTGA TCTAAATAAGGAAAATGAAAAACCAGTTCCCAAATTTGACAAATGTTCAGAAGCAGATTCTTGTAAGCAT TTGTCTTTAGATGAATTAGAAGAAGGCGAAATTAGAAGTGATGATGAAGAATCTGTAGCACAAAAACGCT TGGAAAAGAGTGCAAGACCTAGAGTTTCTGCTGAAGTGCAGCCAGGGAAAAGCAGCCCAGGAAGCAGGAG GAGCACTGTGCATGTGCATAAGGACAACGGGAGGACTGCTGTAAAACTCCCTCGGGACAGACTCACATGG AGCAAAAGATCAAGTGAATCAAGACCCTCCAACACCGAAAGGAAAAGTAAAACAATGAGCATCTCCAGCT TGGAAAAAATACTTCCGCTTATCCTTGTACCCTCTTCCCTGTGGGAGGTTATGCATATGTTACGGTTGCT AGGTAAACATGTAAGAAAAAATTATATGAAATTCAAGATAAAATTTTCATTGACACAATTTCATAGAATT ATTGAATCTGCAATTTTGAGTTTCACATCACTAGTTAAATGCCTTGATTTGTCTAAGATCTGTAAGTCAG TAAGTACTTTACAAAAGAGTCTTTGTGAAGTTATAGAATCTAACCTTAAACAAGTGAAGAAGAATGGCAT AGTTGACCGTTTATTTGAACAGCAACAAACAGATATGAAAAAAAAATTGTGGAAGTTTGTAGATGAACAA CTTGATTATTTGTTTGAAAAGCTTAAAAAAATCCTACTAAAGTTTTGTGATTCTGTAAACTTTGAAAATG AGAATAGTGAAGGAAAACTTGGAAAAAAATATAAAGAGAGAACCCAACATTCAAATTGTCAGAAGAAAAA AATGGACAACAAAGAAATACGGAGAGAAAAAGTGCTAAAATCAGAAAATACTGTGAATTTTAAATCTTCA CTGGGATGTGAAAAATCTGAAGAAAAACATCAGGACCAAAATAAAACCAATGCTAGTATAGTAAAGCATG ATGTAAAAAGAACTTTTAGCACTTGCAGTGATAATACAAAGAACGCTGAATGTAAAGAGCAGTTTCTGGA AAAGAGCTGCCCGAGTACCCCTAGGCCAGGAAAAGATGAAGGACATACTGAGGAGGAGGCACAGGCGGCA CAGCATGCAAGTGCTAAGTCCGAACGGAGCTTTGAGATCCTTACTGAGCAGCAGGCATCCAGCCTTACTT TTAACTTAGTGAGTGATGCACAGATGGGTGAGATATTTAAAAGCTTGCTACAAGGTTCTGATCTGTTGGA CACAAGTGGCACTGAAAAGGCAGAGTGGGAATTAAAGACTCCAGAGAAACAGCTGCTGGAAAGCCTCAAG TGTGAATCTGCACCAGCTTGTGCAACAGAAGAGCTGGTTTCAGAGGGGGCTTCTCTTTGTCCAAAAGTGA TCAGTGATGATAATTGGTCTTTATTATCATCTGAAAAGGGTCCATCTTTATCTTCAGGGCTTTCACTGCC AGTTCATCCTGATGTGTTAGATGAAAATTGTATGTTTGAAGTATCTTCTAACACTGCTTTAGGTAAAGAT AATGTATACAGCTCAGAAAAGAGTAAGCCCTGCATCTCTTCCATACTCTTAGAAGATCTTGCGGTCTCTT TAACAGTACCGTCACCTCTGAAATCAGATGGCCATTTGAGTTTCTTAAAGCCAGAAGTTTTGTCAACTTC AACTCCTGAAGAAGTTATTAGTGCACATTTTAGTGAGGATGCTTTGCTTGAGGAAGAGGATGCATCTGAA CAGGACATTCATCTAGCTCTGGAGTCTGATAACTCAAGCAGTAAGTCAAGCTGTTCATCATGGACAAGCC GGTCTGTTGCTTCAGGCTTTCAGTACCACCCTAATCTTCCCATGCATGCTGTCATAATGGAAAAGTCCAA TGATCATTTCATTGTGAAAATACGGCGTGCAACACCATCTACCTCCCCTGGCCTTAAACATGGTGTGGTA GCTGAGGAGTCATTGACATCTTTGCCTAGAACTGGAAAAGAAGCTGGTGTAGCAACAGAGAAAGAACCTA ACCTGTTTCAGAGTACAGTTTTAAAACCTGTCAAGGACTTGGAAAATACTGATAAAAATATTGATAAGAG TAAACTAACTCATGAAGAACAGAACTCTATAGTACAAACACAGGTTCCAGATATATATGAATTTCTTAAA GATGCCTCAAATAAGGTGGTTCATTGTGATCAAGTGGTTGATGATTGCTTCAAGTTGCATCAAGTATGGG AACCAAAAGTTTCTGAGAACCTTCAAGAGTTGCCTTCAATGGAGAAAATCCCACACTCTCTTGATAATCA TCTTCCTGATACACACATAGATCTAACGAAAGATTCAGCCACTGAGACCAAAAGCTTGGGGGAGCTAATG GAAGTAACAGTTTTAAATGTTGATCACTTGGAATGTTCTCAAACCAACTTAGATCAAGATGCAGAGATAA CATGTAGTTCTTTACAGCCTGATACTATAGATGCTTTTATTGATTTGACACATGATGCTTCAAGTGAGAG TAAAAATGAAGGTAGTGAACCTGTGTTAGCTGTTGAAGGTATGGGATGCCAGGTAATATGTATAGATGAG GATACCAACAAAGAAGGAAAGATGGGAAGGGCAAACAGTCCTTTAGAAAGTATTGTTGAAGAAACTTGTA TTGATTTGACCTCAGAGTCTCCTGGCTCCTGTGAAATCAAGAGACATAATTTAAAGTCGGAGCCTCCATC AAAGTTGGATTGTTTAGAGTTGCCTGAAACTCTGGGTAATGGTCACAAGAAGAGGAAAAACAGTCCTGGT GTTAGTCACTCTTCTCAGAAAAAACAAAGAAAGGACATAGACTTAAGTAGTGAAAAGACCCAGAGACTTA GTCCCAATTCTGATAGAAATGGTGATGCTCACAGAAAGCAAGCGAGCAAGAAAAGAGAACCTGCAGTAAA TGAAACGTCCTTGTCATCAGAGGCCAGCCCAGAGGTGAAGGGTTCAACAGCAGTACTTGCTGCTTCCCCA GCAAGCCTTTCTGCAAAAAATGTTATCAAAAAGAAGGGAGAAATTATAGTTTCATGGACAAGAAATGATG ACCGGGAAATTTTACTGGAATGTCAGAAAAGAATGCCGTCCCTGAAAACATTTACTTATTTAGCTGTCAA GCTGAATAAAAATCCAAATCAGGTTTCAGAGAGGTTCCAGCAGCTGAAAAAGCTCTTTGAGAAGTCAAAA TGCAGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_011997 |
Insert Size | 5889 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_011997.3, NP_036127.2 |
RefSeq Size | 6813 bp |
RefSeq ORF | 5889 bp |
Locus ID | 26885 |
UniProt ID | Q9WUF3 |
Cytogenetics | 4 14.27 cM |
Gene Summary | Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation (By similarity). Required for histone gene transcription and progression through S phase (By similarity). Required for histone gene transcription and S phase progression (By similarity). Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
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