Taok2 (NM_001163775) Mouse Untagged Clone
CAT#: MC224047
Taok2 (untagged) - Mouse TAO kinase 2 (Taok2), transcript variant 2, (10ug)
"NM_001163775" in other vectors (4)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Taok2 |
Synonyms | 1110033K02Rik; B230344N16; MAP3K17; mKIAA0881; PSK; PSK1; TAO1; TAO2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC224047 representing NM_001163775
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCAGCTGGGGGCCGGGCCGGGAGCCTGAAGGACCCTGATGTGGCTGAGCTCTTCTTCAAGGATGACC CTGAGAAGCTCTTCTCTGACCTCCGGGAGATCGGCCATGGCAGCTTTGGAGCAGTGTACTTTGCCCGGGA TGTCCGGAACAGTGAGGTGGTGGCCATCAAGAAGATGTCCTATAGTGGGAAGCAATCAAATGAGAAATGG CAGGATATCATCAAGGAAGTGCGGTTCTTACAGAAGCTACGGCATCCTAATACCATTCAGTACCGGGGCT GTTACCTGAGGGAGCACACAGCTTGGCTGGTGATGGAGTATTGCCTGGGCTCAGCTTCTGATCTTCTAGA AGTGCACAAGAAACCCCTGCAGGAGGTAGAGATTGCAGCTGTGACCCATGGGGCTCTTCAGGGCCTGGCA TATCTACACTCACACAACATGATCCATAGAGATGTGAAGGCTGGAAACATCTTGCTGTCAGAACCAGGCT TGGTAAAACTGGGGGACTTTGGCTCTGCGTCAATCATGGCACCTGCCAACTCTTTTGTGGGTACTCCATA CTGGATGGCTCCAGAGGTGATCCTAGCCATGGATGAGGGACAATATGATGGCAAAGTGGATGTCTGGTCC TTGGGGATAACCTGTATTGAGCTAGCGGAGCGGAAGCCACCACTGTTCAACATGAATGCAATGAGTGCCT TATACCACATTGCACAGAATGAATCTCCTGCTCTCCAGTCAGGACACTGGTCTGAGTACTTCCGGAATTT TGTTGACTCCTGTCTTCAGAAAATCCCTCAAGACAGACCAACCTCAGAGGTTCTTTTGAAGCACCGCTTT GTGCTCCGGGAGCGACCGCCCACAGTCATCATGGACCTAATCCAGAGGACCAAGGATGCTGTACGGGAAC TGGATAACCTGCAGTACCGAAAGATGAAGAAGATACTGTTCCAAGAGGCACCCAATGGCCCTGGTGCTGA GGCCCCAGAGGAAGAGGAGCTCACACCCTGTTCCCAGGAGGCAGAACCTTACACGCACCGTGCAGGGACA CTGACCAGTCTAGAGAGCAGCCATTCAGTGCCCAGCATGTCCATCAGCGCCTCCAGCCAGAGCAGCTCAG TCAACAGCCTAGCAGATGCCTCAGATAATGAAGAAGAGGAGGAAGAAGAAGAGGAAGAGGAGGAGGAGGA GGAGGAAGAAGGCCCTGAATCCAGAGAGATGGCCATGATGCAGGAGGGGGAGCATACAGTCACTTCCCAC AGCTCCATCATCCACCGGCTGCCGGGCTCAGACAACCTATATGATGATCCCTACCAGCCAGAGATGACCC CAGGTCCACTCCAGCCACCTGCAGCCCCTCCCACCTCCACCTCCTCTTCTGCTCGCCGCAGAGCTTATTG CCGCAACCGAGACCACTTTGCTACCATTCGTACTGCCTCCCTGGTCAGCCGTCAGATCCAGGAGCATGAG CAGGACTCAGCCCTGCGAGAGCAGCTGAGTGGCTACAAGCGGATGCGACGTCAGCACCAGAAGCAACTGC TGGCCCTGGAGTCCCGTCTGAGGGGTGAACGTGAGGAGCACAGTGGGCGGTTACAGCGGGAGCTCGAGGC ACAGCGGGCTGGCTTTGGGACCGAGGCTGAGAAGCTGGCCCGGAGGCACCAGGCCATTGGTGAGAAGGAG GCACGGGCTGCTCAGGCGGAGGAGCGGAAGTTCCAGCAGCACATCCTGGGGCAGCAGAAGAAGGAGCTGG CCGCCCTGCTGGAGGCGCAGAAGCGAACCTACAAGCTGCGGAAGGAGCAGTTGAAAGAGGAGCTCCAGGA GAACCCTAGCACACCCAAACGAGAGAAGGCTGAGTGGCTGTTGAGGCAAAAGGAGCAGTTGCAACAGTGC CAGGCAGAAGAGGAAGCGGGGCTGCTGCGGAGGCAGCGCCAGTACTTTGAACTTCAGTGTCGCCAATACA AGCGCAAGATGCTACTGGCTCGGCACAGCCTAGATCAGGACCTGCTTCGAGAGGACTTGAATAAGAAACA GACACAGAAGGACTTGGAGTGTGCTCTGCTGTTACGGCAGCATGAGGCTACCCGAGAGCTGGAGCTAAGA CAGCTCCAGGCTGTCCAGCGCACACGTGCTGAACTTACCCGCCTTCAGCACCAGACAGAACTAGGCAACC AGCTGGAGTACAACAAGCGACGGGAGCAAGAATTACGGCAGAAGCACGCGGCCCAGGTTCGCCAGCAGCC CAAGAGCCTCAAAGTACGTGCAGGCCAGCTACCCATGGGCCTCCCTGCTACTGGGGCTCTGGGACCACTC AGCACAGGCACCCCTAGTGAAGAGCAGCCTTGCTCATCTGGCCAGGAGGCAATCCTGGACCAAAGGATGC TGGGAGAGGAGGAGGAAGCAGTGCCAGAGAGAAGGATTCTGGGAAAGGAAGGGACTACCTTGGAGCCAGA GGAGCAGAGGATTCTGGGGGAAGAAATGGGAACCTTTAGTTCCAGCCCACAAAAACATAGGAGTCTGGCT AATGAGGAAGATTGGGATATATCTGAGGAGATGAAGGAGATTAGAGTCCCATCACTGGCATCCCAGGAGA GAAATATTATTGGCCAGGAAGAGGCAGCGGCATGGAGTCTGTGGGAGAAGGAGGGTGGGAACCTTGTGGA TGTGGAGTTCAAGCTTGGCTGGGTCCAGGGTCCAGTTCTGACTCCAGTCCCGGAGGAGGAAGAGGAGGAG GAAGAAGAGGGAGGGGCTCCAATTGGAACCCACAGGGACCCTGGAGATGGCTGTCCTTCCCCAGATATCC CCCCAGAGCCACCTCCATCACATCTGAGACAGTACCCTACTAGCCAGCTCCCTGGACTCCTGTCTCATGG CCTCCTGGCTGGCCTATCCTTTGCAGTGGGGTCCTCCTCTGGCCTCCTGCCCCTACTCCTCCTGCTGCTA CTCCCATTGCTGGCAGCCCAGGGTGGAGGTGGCTTGCAGGCAGCACTGCTGGCCCTTGAGGTAGGGCTAG TGGGCCTGGGGGCCTCCTACCTGTTCCTTTGTACAGCTCTACACCTGCCCCCCGGTCTGTTCTTACTCCT GGCTCAGGGTACTGCACTGTTGGCTGTCCTTAGCCTGAGCTGGCGCAGAGGCCTTATGGGTGTGCCTCTG GGCCTTGGGGCTGCCTGGCTCCTAGCTTGGCCCAGCCTGGCTTTACCTCTGGCAGCTATGGCAGCTGGGG GCAAATGGGTACGGCAACAAGGCCCCCAGATGCGTCGGGGTATCTCTCGACTCTGGTTGAGGATTTTGCT ACGCCTGTCACCCATGGTCTTTCGGGCCCTACAGGGCTGTGGGGCTGTAGGAGACCGGGGGCTGTTTGCC CTGTACCCTAAGACCAATAAGAATGGTTTCCGAAGTCGACTACCTGTCCCTTGGCCCCGTCAGGGAAATC CTCGCACTACTCAACACCCCCTAGCTCAGTTAACAAGAGTTTGGGCTGTGTGCAAGGGCTGGAACTGGCG CCTAGCACGGGCTAGCCACAGATTAGCTTCTTGCTTGCCCCCCTGGGCTGTTCATATACTAGCCAGCTGG GGCCTGCTTAAGGGTGAACGGCCTAGTCGGATCCCTCGGCTGCTGCCACGCAGCCAACGCCGTCTTGGGC TCTCTGCTTCCCGACAGCTACCACCAGGGACTGTAGCTGGGCGGAGATCTCAGACTCGCAGGACCCTGCC TCCCTGGAGGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001163775 |
Insert Size | 3723 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001163775.1, NP_001157247.1 |
RefSeq Size | 5270 bp |
RefSeq ORF | 3723 bp |
Locus ID | 381921 |
UniProt ID | Q6ZQ29 |
Cytogenetics | 7 F3 |
Gene Summary | Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. May affect microtubule organization and stability. May play a role in the osmotic stress-MAPK8 pathway. Prevents MAP3K7-mediated activation of CHUK, and thus NF-kappa-B activation. Isoform 2, but not isoform 1, is required for PCDH8 endocytosis. Following homophilic interactions between PCDH8 extracellular domains, isoform 2 phosphorylates and activates MAPK14/p38 MAPK which in turn phosphorylates isoform 2. This process leads to PCDH8 endocytosis and CDH2 cointernalization. Both isoforms are involved in MAPK14/p38 MAPK activation (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG215627 | Taok2 (tGFP-tagged) - Mouse TAO kinase 2 (Taok2) transcript variant 2, (10ug) |
USD 1,279.00 |
|
MR215627 | Taok2 (Myc-DDK-tagged) - Mouse TAO kinase 2 (Taok2), transcript variant 2 |
USD 1,079.00 |
|
MR215627L3 | Lenti ORF clone of Taok2 (Myc-DDK-tagged) - Mouse TAO kinase 2 (Taok2), transcript variant 2 |
USD 1,379.00 |
|
MR215627L4 | Lenti ORF clone of Taok2 (mGFP-tagged) - Mouse TAO kinase 2 (Taok2), transcript variant 2 |
USD 1,379.00 |
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