Csnk1g2 (NM_134002) Mouse Untagged Clone

CAT#: MC200463

Csnk1g2 (untagged) - Mouse casein kinase 1, gamma 2 (Csnk1g2), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Csnk1g2
• Synonyms: 2810429I12Rik; AI463719
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004839 sequence for NM_134002
  GGAGCCGGAGCGGGGGCCCGAGCCGGAGCGCGAACGTGCGCGGGGCCCGGAGCGGGGGACGCCGCGCTGC TGAGCTCGGCCACCGCCGCCCGCGGGCCCCAGGCGGGGCGCAGCTGGGCACCACAAGATTTAAGGCAGTG GGACCTGTTGGCAGAATGTCTTCTCTCTCTGCAAGCAACCCTGAAGCCACCAAGATGAGCACCCCAGTCC GGCCTGTGAGCGTACCCGGGTGTCAATAGCCGGGAGCCGAGGGGCCACCGGGAGCAATGGTGTACTAGGC CGGGCGCGAGCTCAGGTTTCGCACTCGGATCTCACGGCAGAGTCACCGTGGAGAGGCCAGGGTACCACAA ACTTATGGATTTTGACAAGAAAGGAGGGAAGGGGGAGTTGGAGGAGGGCAGGAGAATGTCCAAAACCGGC ACGAGTCGGAGCAACCACGGCGTCCGCAGTTCGGGGACCAGCTCAGGGGTCCTGATGGTGGGCCCAAACT TCCGAGTCGGCAAGAAGATAGGCTGTGGGAACTTCGGGGAGCTTCGCCTAGGAAAGAATCTGTATACAAA TGAGTACGTGGCTATCAAGCTGGAGCCCATCAAGTCCCGGGCCCCACAGCTGCACCTGGAGTACCGCTTT TACAAGCAGCTCAGCACGACAGGTGAGGCGGACTCGGGTACGGGGCCAGCACTCCTAGGCCAGCAGTGGC TCCGGACACCCAGCATGGATGTTTCCTTCGCAGAGGGCGTCCCTCAGGTCTACTACTTCGGCCCTTGTGG GAAGTACAACGCCATGGTGCTGGAGCTGCTGGGGCCCAGCCTGGAGGACCTTTTCGACCTGTGCGACCGC ACCTTCACGCTGAAGACGGTGCTGATGATCGCCATCCAGCTGATCACGCGCATGGAGTACGTGCACACCA AGAGCCTCATCTACCGTGACGTGAAGCCCGAGAACTTCCTGGTTGGGCGGCCGGGCAGCAAGCGGCAGCA CTCCATCCACATCATCGACTTTGGGCTGGCCAAGGAGTACATCGACCCTGAGACTAAGAAGCACATCCCA TATCGCGAGCACAAGAGCCTGACAGGCACTGCGCGCTACATGAGCATCAACACGCACTTGGGCAAAGAGC AGAGCCGCCGGGATGACCTGGAGGCGCTGGGACACATGTTCATGTACTTCCTGCGCGGCAGTCTGCCCTG GCAGGGGCTCAAGGCAGACACGCTGAAGGAGCGCTACCAGAAGATTGGAGACACCAAGCGTGCCACACCA ATCGAGGTGCTGTGTGAGAGCTTCCCGGAGGAGATGGCCACCTATTTGCGCTATGTGCGGCGCCTAGACT TTTTTGAGAAGCCAGACTACGACTACCTGAGGAAGCTCTTCACTGACCTCTTTGACCGCAGCGGCTACGT GTTTGACTACGAGTATGACTGGGCCGGCAAGCCCCTGCCGACACCCATCGGCACCGTCCACCCTGACGTG CCCTCCCAGCCACCACATCGCGACAAAGCTCAGCTCCACACCAAGAACCAGGCGCTCAACTCCACTAATG GAGAGCTGAACACAGACGACCCCACCGCGGGCCACTCCAACGCCCCCATCGCGGCCCCCGCAGAAGTAGA GGTGGCAGATGAAACAAAGTGCTGCTGCTTCTTCAAGAGGAGAAAGAGAAAATCGCTGCAGCGACATAAG TGAGGGTGGGTGCAGCCGCTCAAGATCCCCAGGCGGGTGTCTAGGAAACTGGCAGTGTCCTTGGTGGTGT GGGGCTCCTTGGCCCACCTGCAGGCACCATCTTTCGGGACTTGGGGTCCCTTCCTTCACACAGGACTTTG GCGGAAATCTCTACACCCGTGTCTCATCATCCCCTTCGAGAGCATTAACTATTTAAACCCAGGAGAGAAG CGCTGTGCCGTCCCTGCTGCGCCCCTGTTAGCTCATAAAGTCCAGCTTGTCCCCTCAATCCAAAGGCCAT TTTCTCGAGGGGGGCAGGCCCGGGGCATGGGTGTCACATGGGGAGGCCTCAGCCACCAAAGGGGAGGCGC GTGCACTTCCACAATGCTGCACCAAAGCCGGGGCGGAGCGCGGGACGGTCACCGCATAGGGACTGGTATG GGCCCCACAGTACCAGGGCGGCCGTGATCCGTGTCCCTGCGTGCAGGGCCCACGGGACAGAATCGCCTTA ACGCCAGGCCTGGGGCAGCAGAGAGGCGGTCCCACAGGAGGGCCAGGCCTTGGTCGTGGGAACTGAGTTC TTGCTTTACGACGTGTACAGAAATGAACTTATGTTTCTCTGGCGCTTCCTTGAAGCCGTAGAGTTTAGGG GCTTTTTTTTAAAAAAAAAAATAAAAGAAAAGAAAAACAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_134002
• Insert Size: 1329 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004839, AAH04839
• RefSeq Size: 2363 bp
• RefSeq ORF: 1329 bp
• Locus ID: 103236
• UniProt ID: Q8BVP5
• Cytogenetics: 10 C1
• Gene Summary: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.