BMP6 (NM_001718) Human 3' UTR Clone

CAT#: SC214295

3' UTR clone of bone morphogenetic protein 6 (BMP6) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: BMP6
• Synonyms: VGR; VGR1
• ACCN: NM_001718
• Insert Size: 1415 bp
• Sequence Data:
  Insert Sequence

  >SC214295 3’UTR clone of NM_001718
  The sequence shown below is from the reference sequence of NM_001718. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  ATGGTTGTAAGAGCTTGTGGATGCCACTAACTCGAAACCAGATGCTGGGGACACACATTCTGCCTTGGA
  TTCCTAGATTACATCTGCCTTAAAAAAACACGGAAGCACAGTTGGAGGTGGGACGATGAGACTTTGAAA
  CTATCTCATGCCAGTGCCTTATTACCCAGGAAGATTTTAAAGGACCTCATTAATAATTTGCTCACTTGG
  TAAATGACGTGAGTAGTTGTTGGTCTGTAGCAAGCTGAGTTTGGATGTCTGTAGCATAAGGTCTGGTAA
  CTGCAGAAACATAACCGTGAAGCTCTTCCTACCCTCCTCCCCCAAAAACCCACCAAAATTAGTTTTAGC
  TGTAGATCAAGCTATTTGGGGTGTTTGTTAGTAAATAGGGAAAATAATCTCAAAGGAGTTAAATGTATT
  CTTGGCTAAAGGATCAGCTGGTTCAGTACTGTCTATCAAAGGTAGATTTTACAGAGAACAGAAATCGGG
  GAAGTGGGGGGAACGCCTCTGTTCAGTTCATTCCCAGAAGTCCACAGGACGCACAGCCCAGGCCACAGC
  CAGGGCTCCACGGGGCGCCCTTGTCTCAGTCATTGCTGTTGTATGTTCGTGCTGGAGTTTTGTTGGTGT
  GAAAATACACTTATTTCAGCCAAAACATACCATTTCTACACCTCAATCCTCCATTTGCTGTACTCTTTG
  CTAGTACCAAAAGTAGACTGATTACACTGAGGTGAGGCTACAAGGGGTGTGTAACCGTGTAACACGTGA
  AGGCAATGCTCACCTCTTCTTTACCAGAACGGTTCTTTGACCAGCACATTAACTTCTGGACTGCCGGCT
  CTAGTACCTTTTCAGTAAAGTGGTTCTCTGCCTTTTTACTATACAGCATACCACGCCACAGGGTTAGAA
  CCAACGAAGAAAATAAAATGAGGGTGCCCAGCTTATAAGAATGGTGTTAGGGGGATGAGCATGCTGTTT
  ATGAACGGAAATCATGATTTCCCTTGTAGAAAGTGAGGCTCAGATTAAATTTTAGAATATTTTCTAAAT
  GTCTTTTTCACAATCATGTACTGGGAAGGCAATTTCATACTAAACTGATTAAATAATACATTTATAATC
  TACAACTGTTTGCACTTACAGCTTTTTTTGTAAATATAAACTATAATTTATTGTCTATTTTATATCTGT
  TTTGCTGTAACATTGAAGGAAAGACCAGACTTTTAAAAAAAAAGAGTTTATTTAGAAAGTATCATAGTG
  TAAACAAACAAATTGTACCACTTTGATTTTCTTGGAATACAAGACTCGTGATGCAAAGCTGAAGTTGTG
  TGTACAAGACTCTTGACAGTTGTGCTTCTCTAGGAGGTTGGGTTTTTTTAAAAAAAGAATTATCTGTGA
  ACCATACGTGATTAATAAAGATTTCCTTTAAGGCA
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001718.6
• Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
• Locus ID: 654
• MW: 54.2