Kallikrein 7 (KLK7) (NM_139277) Human 3' UTR Clone

CAT#: SC212173

3' UTR clone of kallikrein-related peptidase 7 (KLK7) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: KLK7
• Synonyms: hK7; PRSS6; SCCE
• ACCN: NM_139277
• Insert Size: 1100 bp
• Sequence Data:
  Insert Sequence

  >SC212173 3’UTR clone of NM_139277
  The sequence shown below is from the reference sequence of NM_139277. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  ATAAATGACACCATGAAAAAGCATCGCTAACGCCACACTGAGTTAATTAACTGTGTGCTTCCAACAGAA
  AATGCACAGGAGTGAGGACGCCGATGACCTATGAAGTCAAATTTGACTTTACCTTTCCTCAAAGATATA
  TTTAAACCAACCTCATGCCCTGTTGATAAACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAA
  AGAAACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAACTGGAC
  GTTCGTACAGTCTTTACGGAAGACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCC
  AGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAAAAAAATCCAAAATGTAGAACAAGACTTGAATT
  TACCATGATATTATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCT
  TAAATAATAGTCTGGCTTGGCACAACGATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTG
  CAATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCA
  GCCTCCCAAGTACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTATTTTTACTA
  GAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCACCCACCTTG
  GCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACAATGATATTACAAACCTAT
  TAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACATTTAGGCTATAGGATGTTAAATGAC
  AAAAGGAAGGACAAAAATATATATGTATGTGACCCTACCCATAAAAAATGAAATATTCACAGAATCAGA
  TCTGAAAACACATGTCCCAGACTGCATACTGGGGTCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTT
  TCCTTGAATGTGCACTTTTATAACATGAAAAATAAAGGTGGGGAAAAAAGTCAAAAAAAAAAAAA
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_139277.2
• Summary: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
• Locus ID: 5650
• MW: 42.2