Kallikrein 7 (KLK7) (NM_139277) Human 3' UTR Clone
CAT#: SC212173
3' UTR clone of kallikrein-related peptidase 7 (KLK7) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | KLK7 |
Synonyms | hK7; PRSS6; SCCE |
ACCN | NM_139277 |
Insert Size | 1100 bp |
Sequence Data |
>SC212173 3’UTR clone of NM_139277
The sequence shown below is from the reference sequence of NM_139277. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATAAATGACACCATGAAAAAGCATCGCTAACGCCACACTGAGTTAATTAACTGTGTGCTTCCAACAGAA AATGCACAGGAGTGAGGACGCCGATGACCTATGAAGTCAAATTTGACTTTACCTTTCCTCAAAGATATA TTTAAACCAACCTCATGCCCTGTTGATAAACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAA AGAAACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAACTGGAC GTTCGTACAGTCTTTACGGAAGACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCC AGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAAAAAAATCCAAAATGTAGAACAAGACTTGAATT TACCATGATATTATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCT TAAATAATAGTCTGGCTTGGCACAACGATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTG CAATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCA GCCTCCCAAGTACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTATTTTTACTA GAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCACCCACCTTG GCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACAATGATATTACAAACCTAT TAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACATTTAGGCTATAGGATGTTAAATGAC AAAAGGAAGGACAAAAATATATATGTATGTGACCCTACCCATAAAAAATGAAATATTCACAGAATCAGA TCTGAAAACACATGTCCCAGACTGCATACTGGGGTCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTT TCCTTGAATGTGCACTTTTATAACATGAAAAATAAAGGTGGGGAAAAAAGTCAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_139277.2 |
Summary | This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011] |
Locus ID | 5650 |
MW | 42.2 |
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