TLR5 (NM_003268) Human 3' UTR Clone
CAT#: SC212140
3' UTR clone of toll-like receptor 5 (TLR5) for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | TLR5 |
Synonyms | MELIOS; SLE1; SLEB1; TIL3 |
ACCN | NM_003268 |
Insert Size | 1081 bp |
Sequence Data |
>SC212140 3’UTR clone of NM_003268
The sequence shown below is from the reference sequence of NM_003268. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCGTTGCAAACTGTAGCAACCATCTCCTAATCAAAGGAGCAATTTCCAACTTATCTCAAGCCACAAATA ACTCTTCACTTTGTATTTGCACCAAGTTATCATTTTGGGGTCCTCTCTGGAGGTTTTTTTTTTCTTTTT GCTACTATGAAAACAACATAAATCTCTCAATTTTCGTATCAACACCATGTTCTGTCTCACTAACCTCCA AATGGAAAATAATAGATCTAGAAAATTGCAACTGCCCTTAGAGGTTTCCAGTCTCCATTGATTTTCTTT CAGATCCAATAATACCGTTCTGTCCTGCTGTGTTGATTATGGAATGTATCCTAATCATGGGAAGGGCAC CTTGGGAGAAGTTGCAGATGGCTGACGTGCTTTCTCTAGCATTCAGCTAAAAAATGGGATGGTCCATGA TTCTGCGTTCTCTGTGTTCTGCAAAACAACATTAAGTAGAAAACAAACAGAAGCAGAGGCACATTTCCT TCTTTTGCCACAGAAACAATGCCACTGTTGAGTGCAAGTCACACTTTGTCTCATAGATAAGAGGTGGCC CCAAAGAAGCTGGGATGAATGAGTCACTACCTGTCTTGTGACTGTACTGCACTTCATGTTCTTACCTTC GGCTTCTCCAGGTCTCGCCCTAGTGAGCCAAGAACTTTCTCTCACATGCTGCCTTTATTTAAGCCTGGC CTTCAAGACCTTCCATGATTTATCACCAACCTACCTTTTCAGCTTTGTTTCCTAGCACACCTCATTGAT CAGCTGCTCAGGCTGTTGCATGAAGAACATGGACTTTGCACACAGATCCTGGGTTGAGTTCTGAGTCAG CTGTGTATTAGCCATGTAACCTTGGCCTTGGTATGCCCTTGCTGGACCTACATTTTCTCACGTAACAGC ATCTATGTCATAGAATTCCTGTGAAAATTAAATTGGCCAAGGATGTCAGGGCTTCTCAGATCTTTTCCT TCGTTGCCCTAATGACCACAAGAGAACACATACACTGAAGGCCTCCTGGGGGGCAGTTGCAATTTCACT GAAGTTGTATTTTTTTATCTTAAATGAAATCTATGTGTATTTTCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_003268.6 |
Summary | This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009] |
Locus ID | 7100 |
MW | 41.1 |
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