C1ORF190 (LURAP1) (NM_001013615) Human 3' UTR Clone

CAT#: SC212069

3' UTR clone of chromosome 1 open reading frame 190 (C1orf190) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: LURAP1
• Synonyms: C1orf190; LRAP35a; LRP35A
• ACCN: NM_001013615
• Insert Size: 1066 bp
• Sequence Data:
  Insert Sequence

  >SC212069 3’UTR clone of NM_001013615
  The sequence shown below is from the reference sequence of NM_001013615. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  CAGTGCCAGGATGATGTGACCTTCTTGTAACAACTATTCCACCCTTTTGTAATCCTGTGGCTCTTTTAT
  CCATTAGATGTGGTCTCCCCCAAAATTGATTCTCCCTCAGTCTGAGACTAGGAAGAGGCTGCACTGAAA
  TCAGTTACCATGGAAACCTGGCTCATCATTTCTCTAGTCCCTAGGGAGTCTCTGCCTTTATCCCTCAAT
  TATTGGGTCCCTAGAGCTAGCTTGCTCTTTCTTTCTTTCTTTCTTTTTTTGAGACAGGGTCTTATGCTG
  TTACCCAAGATAGAGAGCAGTGGCATGATCACAGCTCACTGCAGCCTTGACCTCCTGGGCTCAAGCGAT
  CCTCCTATTTCAGCCTCCCCCATAGTTAGGACCACAGGCATGCACCACCATGCCCAGCTAATTGTTTAT
  TTATTTATTTTTTTTTTGTAGAGATAGGGTTTCCCTGTGTTGCCCAGGCTGGTCTCAAACTCCTGGGCT
  CAAGGGATCCTCCCGCCTCAGCCTCCCAAAGTGCTGGGATTATGCCCAGCCCCTAGAGATACTTCTATA
  GAGATATTGACTCTAAAGGATTGACCTATGGCTTTTGGTATTTAGTATCTCTCACTACTCCCCCCAGCT
  AAGTAAGGATTTAAGGAATTTAGGACTCCCTGGAGTTAACAGATGAAGAGATGGGGGCATAATTACTTC
  ACCCAAAGTCTAGAAGCCTTGGCCTCTCTCTTGGCCAAGATGGAGGATTGAGGAGGGACATGGACCTTC
  AGGACTAACCCTCTATGGATTGGCCCTCCCAGAAGCGTTTGGGCTGGTAGACCCACCCCTTCCTACCTG
  CTGAGTGATGTCATTTCCTGCCAGGATGGGTAGCCCTTTGTACGGGTCCTTGGATGGTAGTAGGTCATA
  TAGGGGCATCTGAGCCCCTGCTGCTAAGTGAGATCACATTATTTATCGTCCATACCATTACTTCTTGTG
  AACAGTAACATGTCACTCCTCCTGGCAGGAAAGTTTCTCATTGTCAGATGTTTGTGCTTCTTTTCAGGT
  CTTACTTTTTAAATAGAGTGTTCTCATTTTA
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001013615.3
• Summary: Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway (PubMed:21048106). In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity).[UniProtKB/Swiss-Prot Function]
• Locus ID: 541468
• MW: 40