MYCBP2 (NM_015057) Human 3' UTR Clone

CAT#: SC209264

3' UTR clone of MYC binding protein 2 (MYCBP2) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: MYCBP2
• Synonyms: Myc-bp2; PAM; Phr; PHR1
• ACCN: NM_015057
• Insert Size: 751 bp
• Sequence Data:
  Insert Sequence

  >SC209264 3’UTR clone of NM_015057
  The sequence shown below is from the reference sequence of NM_015057. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  GGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCAGATCCTTTGTCTACAGAGAGAAAAATTGCCT
  TCATCCCCCAAGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCATTTTTACATCC
  ATGAAAATGAACCATTCACAGTGCAAGAAGGATACCAAATACCATGTACATAATTCTTGCTATGAAAAG
  TTTCCCCATTATTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGTGAGGTGTTTGCATGTGG
  CCATTACCGTCATTGGCCTGTGAAGCATTGGACATTTATAGATAATTGATATAAAAGAATCGCCATGCC
  CATGGACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGTTTATTGTATACTGCCT
  TTTTGTAATCCTGTACAATTGCATCACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGA
  CTGTTATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAAATGTAATAAGTATCACACTGTAT
  ATAAACATATCAATGTTTGTCCTGTATAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTCTA
  GGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTGCCTCATTATCTTGCAGCTGTAA
  ACATATTGGAATGTACATGTCAATAAAACCACTGTACATTTTTATACAGTGATAAAGTCTA
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_015057.5
• Summary: This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017]
• Locus ID: 23077
• MW: 29.1