Tbp7 (PSMC4) (NM_006503) Human 3' UTR Clone
CAT#: SC201503
3' UTR clone of proteasome (prosome macropain) 26S subunit ATPase 4 (PSMC4) transcript variant 1 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | PSMC4 |
Synonyms | MIP224; RPT3; S6; TBP-7; TBP7 |
ACCN | NM_006503 |
Insert Size | 489 bp |
Sequence Data |
>SC201503 3’UTR clone of NM_006503
The sequence shown below is from the reference sequence of NM_006503. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACGAGCAGGAGCATGAGTTTTACAAGTGACCCTTCCCTTCCCTCCACCACACCACTCAGGGGCTGGGG CTTCTCTCGCACCCCCAGCACCTCTGTCCCAAAACCTCATTCCCTTTTTTCTTTACCCAGGATTGGTTT CTTCAATAAATAGATAAGATCGAATCCATTTAATTTCTTCTTAGAAGTTTAACTCCTTTGGAGAATGTG GGCCTTGAATAGGATCCTCTGGGTCCCTCTTAATCTGACAGATGAGCAGACGAGGTGCATGGCCTGGGT TGCAGCTTGAGAGAACCAAAATATTCAAACCAGATGACTTCCAAAATGTGGGGAAAGGGATGGAAAATG AACCTGAGATGGAGTCCTTAATCACGGGATAAAGCCCTGTGCATCTCCCTCATTTCCTACAGGTAAAAG ACAGTAAAGAAATTCAGGTCACAGGCCTTGGGAGTTCATAGGAAGGAGATGTCCAGTGCTGTCCAGTAG AACTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_006503.4 |
Summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
Locus ID | 5704 |
MW | 18.9 |
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