TIM 3 (HAVCR2) Mouse Monoclonal Antibody [Clone ID: OTI4E4]
Specifications
Product Data | |
Clone Name | OTI4E4 |
Applications | FC, WB |
Recommended Dilution | WB 1:2000, FLOW 1:100 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human HAVCR2 (NP_116171) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 33.2 kDa |
Gene Name | hepatitis A virus cellular receptor 2 |
Database Link | |
Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011] |
Synonyms | CD366; HAVcr-2; KIM-3; SPTCL; Tim-3; TIM3; TIMD-3; TIMD3 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF813028 | Carrier-free (BSA/glycerol-free) HAVCR2 mouse monoclonal antibody,clone OTI4E4 |
USD 600.00 |
|
TA813028 | HAVCR2 mouse monoclonal antibody,clone OTI4E4 |
USD 447.00 |
|
TA813028AM | HAVCR2 mouse monoclonal antibody,clone OTI4E4, Biotinylated |
USD 509.00 |
|
TA813028BM | HAVCR2 mouse monoclonal antibody,clone OTI4E4, HRP conjugated |
USD 509.00 |
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