CD160 Mouse Monoclonal Antibody [Clone ID: OTI2G2]
Specifications
Product Data | |
Clone Name | OTI2G2 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-160 of human CD160 (NP_008984) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | CD160 molecule |
Database Link | |
Background | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] |
Synonyms | BY55; NK1; NK28 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF809703 | Carrier-free (BSA/glycerol-free) CD160 mouse monoclonal antibody,clone OTI2G2 |
USD 600.00 |
|
TA809703 | CD160 mouse monoclonal antibody,clone OTI2G2 |
USD 224.00 |
|
TA809703AM | CD160 mouse monoclonal antibody,clone OTI2G2, Biotinylated |
USD 509.00 |
|
TA809703BM | CD160 mouse monoclonal antibody,clone OTI2G2, HRP conjugated |
USD 509.00 |
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