CNOT2 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6D7]

CAT#: TA808695BM

CNOT2 mouse monoclonal antibody, clone OTI6D7 (formerly 6D7), HRP conjugated

Product Images

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CNOT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA808695) (1:150)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CNOT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA808695) (1:150)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-CNOT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA808695) (1:150)

Specifications

Product Data

• Clone Name: OTI6D7
• Applications: IHC
• Recommended Dilution: IHC 1:150
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human CNOT2(NP_055330) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59.6 kDa
• Gene Name: CCR4-NOT transcription complex subunit 2
• Database Link:
  NP_055330
  Entrez Gene 72068 MouseEntrez Gene 299805 RatEntrez Gene 4848 Human
  UniProt ID Q9NZN8
• Background: This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
• Synonyms: CDC36; HSPC131; NOT2; NOT2H

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: RNA degradation