ZIC3 Mouse Monoclonal Antibody [Clone ID: OTI6F7]

CAT#: TA808167

ZIC3 mouse monoclonal antibody, clone OTI6F7 (formerly 6F7)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Cat# PS100001, Left lane) or pCMV6-ENTRY ZIC3 (Cat# RC220375, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZIC3 (Cat# TA808167)(1:500). Positive lysates LY418705 (100ug) and LC418705 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI6F7
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 242-467 of human ZIC3(NP_003404) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50.4 kDa
• Gene Name: Zic family member 3
• Database Link:
  NP_003404
  Entrez Gene 22773 MouseEntrez Gene 7547 Human
  UniProt ID O60481
• Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008]
• Synonyms: HTX; HTX1; VACTERLX; ZNF203

Reference Data

• Protein Families: Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS