DUSP10 Mouse Monoclonal Antibody [Clone ID: OTI2H1]
Specifications
Product Data | |
Clone Name | OTI2H1 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 180-482 of human DUSP10(NP_009138) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | dual specificity phosphatase 10 |
Database Link | |
Background | Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Synonyms | MKP-5; MKP5 |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase |
Protein Pathways | MAPK signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF806771 | Carrier-free (BSA/glycerol-free) DUSP10 mouse monoclonal antibody, clone OTI2H1 (formerly 2H1) |
USD 600.00 |
|
TA806771 | DUSP10 mouse monoclonal antibody, clone OTI2H1 (formerly 2H1) |
USD 447.00 |
|
TA806771AM | DUSP10 mouse monoclonal antibody, clone OTI2H1 (formerly 2H1), Biotinylated |
USD 509.00 |
|
TA806771BM | DUSP10 mouse monoclonal antibody, clone OTI2H1 (formerly 2H1), HRP conjugated |
USD 509.00 |
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