Factor I (CFI) Mouse Monoclonal Antibody [Clone ID: OTI7C9]
CAT#: TA806003
CFI mouse monoclonal antibody, clone OTI7C9 (formerly 7C9)
Size: 30 ul
Formulation: Carrier-Free
USD 867.00
Specifications
Product Data | |
Clone Name | OTI7C9 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 340-583 of human CFI(NP_000195) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 63.4 kDa |
Gene Name | complement factor I |
Database Link | |
Background | This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008] |
Synonyms | AHUS3; ARMD13; C3b-INA; C3BINA; FI; IF; KAF |
Reference Data | |
Protein Families | Druggable Genome, Protease, Secreted Protein |
Protein Pathways | Complement and coagulation cascades |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF806003 | Carrier-free (BSA/glycerol-free) CFI mouse monoclonal antibody, clone OTI7C9 (formerly 7C9) |
USD 600.00 |
|
TA806003AM | CFI mouse monoclonal antibody, clone OTI7C9 (formerly 7C9), Biotinylated |
USD 509.00 |
|
TA806003BM | CFI mouse monoclonal antibody, clone OTI7C9 (formerly 7C9), HRP conjugated |
USD 509.00 |
|
TA806003S | CFI mouse monoclonal antibody, clone OTI7C9 (formerly 7C9) |
USD 200.00 |
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