EPOR Mouse Monoclonal Antibody [Clone ID: OTI4F12]
CAT#: TA804627
EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12)
Size: 30 ul
Formulation: Carrier-Free
Specifications
Product Data | |
Clone Name | OTI4F12 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 25-250 of human EPOR (NP_000112) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | erythropoietin receptor |
Database Link | |
Background | This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
Synonyms | EPO-R |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF804627 | Carrier-free (BSA/glycerol-free) EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) |
USD 600.00 |
|
TA804627AM | EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12), Biotinylated |
USD 509.00 |
|
TA804627BM | EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12), HRP conjugated |
USD 509.00 |
|
TA804627S | EPOR mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) |
USD 200.00 |
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