BBS4 Mouse Monoclonal Antibody [Clone ID: OTI2D5]
USD 867.00
Specifications
Product Data | |
Clone Name | OTI2D5 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 266-519 of human BBS4 (NP_149017) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 58.1 kDa |
Gene Name | Bardet-Biedl syndrome 4 |
Database Link | |
Background | This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein 'BBSome' complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified. [provided by RefSeq, Jan 2009] |
Synonyms | Bardet-Biedl syndrome 4 |
Reference Data |
Documents
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Resources
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF804560 | Carrier-free (BSA/glycerol-free) BBS4 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5) |
USD 600.00 |
|
TA804560 | BBS4 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5) |
USD 447.00 |
|
TA804560AM | BBS4 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5), Biotinylated |
USD 509.00 |
|
TA804560BM | BBS4 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5), HRP conjugated |
USD 509.00 |
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