SETD2 Mouse Monoclonal Antibody [Clone ID: OTI3G8]
Specifications
Product Data | |
Clone Name | OTI3G8 |
Applications | WB |
Recommended Dilution | WB 1:200 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1787-2144 of human SETD2 (NP_054878) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | SET domain containing 2 |
Database Link | |
Background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug |
Synonyms | HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; p231HBP; SET2 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Lysine degradation |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF804268 | Carrier-free (BSA/glycerol-free) SETD2 mouse monoclonal antibody, clone OTI3G8 (formerly 3G8) |
USD 600.00 |
|
TA804268 | SETD2 mouse monoclonal antibody, clone OTI3G8 (formerly 3G8) |
USD 447.00 |
|
TA804268AM | SETD2 mouse monoclonal antibody, clone OTI3G8 (formerly 3G8), Biotinylated |
USD 509.00 |
|
TA804268BM | SETD2 mouse monoclonal antibody, clone OTI3G8 (formerly 3G8), HRP conjugated |
USD 509.00 |
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